BEGIN:VCALENDAR VERSION:2.0 PRODID:-//wp-events-plugin.com//7.2.3.1//EN TZID:Europe/Helsinki X-WR-TIMEZONE:Europe/Helsinki BEGIN:VEVENT UID:186976@bioscience.fi DTSTART;TZID=Europe/Helsinki:20251021T120000 DTEND;TZID=Europe/Helsinki:20251021T130000 DTSTAMP:20250924T073613Z URL:https://bioscience.fi/events/biocity-turku-guest-seminar-prof-mark-dal y/ SUMMARY:BioCity Turku Guest Seminar: Prof. Mark Daly DESCRIPTION:21st October at 12:00-13:00\nOnsite event\nin Presidentti audit orium\, BioCity\n\nProf. Mark Daly\, Massachusetts General Hospital\; Harv ard Medical School\, USA\nFinnGen and the road ahead in human genetics\n\n Host: Teemu Niiranen (tejuni@uti.fi)\n\n \;\n\nMark Daly is the foundi ng Chief of the Analytic and Translational Genetics Unit (ATGU) at Massach usetts General Hospital and Assistant Professor at the Harvard Medical Sch ool. His research has historically focused on the development and applicat ion of statistical methods for the discovery and interpretation of genetic variation responsible for complex human disease\, and with the creation o f the ATGU\, he and other core faculty are focused on the interpretation o f genome sequence and the use of genome information in clinical settings. Mark is also an institute member and co-director of the Program in Medical and Population Genetics at the Broad Institute of MIT and Harvard\, where he leads many large-scale genome sequencing studies in autism and inflamm atory bowel disease.\n\nMark was appointed Director of the Institute for M olecular Medicine Finland (FIMM) at the University of Helsinki from Februa ry of 2018 through April 2023 while maintaining his lab in Boston. He has returned to Boston and maintains an affiliate position at Institute for Mo lecular Medicine Finland. FIMM is a translational research institute focus ing on cancer\, digital diagnostics\, genetics\, and epidemiology and is h ome to landmark efforts such as the FinnGen Project.\n\nWhile developing c omputational and statistical methods that can be broadly applied\, his gro up has several primary medical genetics research foci. He has an extensive research program in neuropsychiatric genetics - particularly in autism\, schizophrenia\, and ADHD – and has led large-scale GWAS and exome sequen cing efforts in this area. His lab and Dr. Ben Neale's lab serve as an ana lytic hub for the Psychiatric GWAS Consortium\, an international consortiu m leading the largest collaborative GWAS studies in 5 major psychiatric di sorders. He also has a longstanding effort in the mapping of genes for Cro hn’s disease and ulcerative colitis\, where he helped found and lead an international effort that has identified more than 150 genetic risk factor s and\, in collaboration with Dr. Ramnik Xavier’s group\, pursues the fu nctional interpretation and clinical ramifications of these continued gene discovery efforts. Along with Dr. Rehm\, he is co-PI of the gnomAD projec t and is committed to ensuring the output of all ATGU genomic research is maximally accessible and useful to the clinical and research communities.\ n\nMark received his B.S. in physics from MIT and his Ph.D. in human genet ics from Leiden University\, Netherlands.\n\n \;\n\nSelected recent pu blications\n\nRare genetic variation in PTPRB is associated with central s erous chorioretinopathy\, varicose veins and glaucoma. Rämö JT\, Gorman BR\, ... \, Palotie A\, Peachey NS\, Turunen JA\, Boon CJ\, Ellinor PT\, I yengar SK\, Daly MJ\, Rossin EJ. Nat Commun. 2025 May 3\;16(1):4127\n\nGen ome-wide association study reveals mechanisms underlying dilated cardiomyo pathy and myocardial resilience. Jurgens SJ\, Rämö JT\, ...\, Palotie A\ , Amin AS\, Charron P\, Meder B\, Ellinor PT\, Daly M\, Aragam KG\, Bezzin a CR. Nat Genet. 2024 Dec\;56(12):2636-2645\n\nPolygenic risk scores as a marker for epilepsy risk across lifetime and after unspecified seizure eve nts. Heyne HO\, Pajuste FD\, Wanner J\, Daniel Onwuchekwa JI\, Mägi R\, P alotie A\; FinnGen\; Estonian Biobank research team\; Kälviainen R\, Daly MJ. Nat Commun. 2024 Jul 25\;15(1):6277\n\nPublic platform with 39\,472 e xome control samples enables association studies without genotype sharing. Artomov M\, Loboda AA\, Artyomov MN\, Daly MJ. Nat Genet. 2024 Feb\;56(2) :327-335 ATTACH;FMTTYPE=image/jpeg:https://bioscience.fi/wp-content/uploads/2025/06 /daly-400px.jpg CATEGORIES:Turku Bioscience Events END:VEVENT BEGIN:VTIMEZONE TZID:Europe/Helsinki X-LIC-LOCATION:Europe/Helsinki BEGIN:DAYLIGHT DTSTART:20250330T040000 TZOFFSETFROM:+0200 TZOFFSETTO:+0300 TZNAME:EEST END:DAYLIGHT END:VTIMEZONE END:VCALENDAR