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UID:187036@bioscience.fi
DTSTART;TZID=Europe/Helsinki:20261112T120000
DTEND;TZID=Europe/Helsinki:20261112T130000
DTSTAMP:20260916T122151Z
URL:https://bioscience.fi/events/frontiers-of-science-prof-miguel-soares/
SUMMARY:Frontiers of Science: Prof. Miguel Soares
DESCRIPTION:12th November at 12:00\nOnsite event\nin Presidentti auditorium
 \, BioCity\nAutumn 2026 poster\n\nProf. Miguel Soares\, Gulbenkian Institu
 te for Molecular Medicine\, Portugal\nMetabolic adaptation as a defence st
 rategy against infection\n\nHost: Antonio Sousa (aggode@utu.fi)\n\nCoffee 
 and sandwich served at 11:45\, first come first serve!\n\n&nbsp\;\n\nSix P
 hD researchers and early-career postdocs are welcome to have lunch and dis
 cuss with Prof. Soares after the seminar. This is a great possibility to l
 earn hosting skills in a friendly environment and create connections for f
 uture. Everyone is welcome to join\, BioCity Turku will offer the lunch.\n
 \nIf you got interested\, please send an email to biocityturku@bioscience.
 fi\n\n&nbsp\;\n\nProf. Soares’ lab studies how immunity evolved in multi
 cellular organisms as a means to limit the fitness costs imposed by symbio
 tic interactions with different classes of microbes. Resistance is a cardi
 nal feature of immunity\, whereby soluble and cellular components of the i
 mmune system sense and target pathogenic microorganisms for containment\, 
 destruction\, or expulsion. In addition\, multicellular organisms deploy a
 nother defense strategy\, referred to as disease tolerance\, which does no
 t target microbes directly. This evolutionarily conserved strategy relies 
 on stress responses that rewire host energy metabolism. At the Inflammatio
 n Laboratory\, researchers aim to identify and characterize how these stre
 ss responses engage inter-organ communication processes that rewire energy
  metabolism in order to limit the fitness costs associated with infections
  caused by different classes of microbes. The objective is to provide a tr
 ansformative understanding of host–microbe interactions and their transl
 ational impact on the treatment of global infectious diseases.\n\n&nbsp\;\
 n\nSelected publications\n\nSoares MP\, Jentho E. Ageing rewires the body'
 s tolerance to infection. Nature. 2026 Feb\;650(8102):558-559\n\nMartins R
 \, Blankehaus B\, Braza F\, Mesquita M\, Ventura P\, Singh S\, Weis S\, Pi
 res M\, Pagnotta S\, Wu Q\, Cardoso S\, Jentho E\, Figueiredo A\, Faísca 
 P\, Nóvoa A\, Morais VA\, Wculek SK\, Sancho D\, Mallo M\, Soares MP. Hom
 eostatic control of energy metabolism by monocyte-derived macrophages. EMB
 O J. 2026 Jan\;45(1):106-150\n\nFigueiredo A\, Rastogi ST\, …\, Portugal
  S\, Kurth F\, Elo LL\, Paul BD\, Martins R\, Soares MP. A metabolite-base
 d resistance mechanism against malaria. Science. 2025 Jun 12\;388(6752):ea
 dq6741.\n\nWu Q\, Sacomboio E\, Valente de Souza L\, Martins R\, Kitoko J\
 , Cardoso S\, Ademolue TW\, Paixão T\, Lehtimäki J\, Figueiredo A\, Nord
 en C\, Tharaux PL\, Weiss G\, Wang F\, Ramos S\, Soares MP. Renal control 
 of life-threatening malarial anemia. Cell Rep. 2023 Feb 28\;42(2):112057\n
 \nSingh S\, Bastos-Amador P\, Thompson JA\, Truglio M\, Yilmaz B\, Cardoso
  S\, Sobral D\, Soares MP. Glycan-based shaping of the microbiota during p
 rimate evolution. Elife. 2021 May 19\;10:e67450.\n\n \n\nGeneral informat
 ion\n\n 	Registration is not needed\, participation list is circulated in 
 the audience.\n 	If you are a student and later wish to get a certificate 
 of attendance from the Frontier of Science seminars (BKEM1020\; UTU)\, pri
 nt out the seminar diary and after the seminar ask the BioCity coordinator
  to sign it https://seafile.utu.fi/d/44a70f80ac1e46a9ad0a/\n 	Please note 
 that any audio or video recording of the seminars is strictly forbidden.\n
  	Autumn 2026 image credits to Samuel Svärd: Whole mount immunofluorescen
 t staining of the mouse retina. Image acquired on 3i CSU-W1 Spinning disk 
 with 10x objective.\n
ATTACH;FMTTYPE=image/jpeg:https://bioscience.fi/wp-content/uploads/2026/09
 /soares-thumbnail.jpg
CATEGORIES:Turku Bioscience Events
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