BEGIN:VCALENDAR VERSION:2.0 PRODID:-//wp-events-plugin.com//7.2.3.1//EN TZID:Europe/Helsinki X-WR-TIMEZONE:Europe/Helsinki BEGIN:VEVENT UID:186912@bioscience.fi DTSTART;TZID=Europe/Helsinki:19700101T000000 DTEND;TZID=Europe/Helsinki:19700101T000000 DTSTAMP:20260417T112743Z URL: SUMMARY:Frontiers of Science: Prof. Vytas Bankaitis DESCRIPTION:\n\nMay 8th at 12:00\nOnsite event\nin Presidentti auditorium\, BioCity\nSpring 2025 program\n\nProf. Vytas Bankaitis\, Texas A&\;M Un iversity\, USA\nLipid-mediated signal transduction: unveiling the role of PITPs in cellular homeostasis and disease\nHost: Max Lönnfors (max.lonnfo rs@abo.fi)\n\nCoffee and sandwich at 11:45\, first come first served!\n\n& nbsp\;\n\nSix PhD researchers and early-career postdocs are welcome to hav e a lunch and discuss with Prof. Bankaitis after the seminar. This is a gr eat possibility to learn hosting skills in a friendly environment and crea te connections for future. Everyone is welcome to join\, BioCity Turku wil l offer the lunch.\n\nIf you got interested\, please send an email to bioc ityturku@bioscience.fi\n\n \;\n\nThe Bankaitis laboratory is intereste d in the regulatory interfaces between novel lipid-mediated signal transdu ction pathways and important cellular functions. The focus of their work i s the phosphatidylinositol/ phosphatidylcholine transfer proteins (PITPs)\ , a ubiquitous but enigmatic class of proteins. Ongoing projects in the la boratory derive from a multidisciplinary approach that encompasses biochem ical characterization of novel members of the metazoan PITP family\, and t he application of genetic\, molecular and biophysical approaches to detail ed structural and functional analyses of PITPs.\n\n \;\n\nSelected pub lications\n\nA novel bivalent interaction mode underlies a non-catalytic m echanism for Pin1-mediated protein kinase C regulation. Chen XR\, Dixit K\ , Yang Y\, McDermott MI\, Imam HT\, Bankaitis VA\, Igumenova TI. Elife. 20 24 Apr 30\;13:e92884. doi: 10.7554/eLife.92884.\n\nPathak A\, Willis KG\, Bankaitis VA\, McDermott MI. 2024. Mammalian START-like phosphatidylinosit ol transfer proteins - Physiological perspectives and roles in cancer biol ogy. Biochim Biophys Acta Mol Cell Biol Lipids. 2024 Oct\;1869(7):159529. doi: 10.1016/j.bbalip.2024.159529\n\nYeh YT\, Sona C\, Yan X\, Li Y\, Path ak A\, McDermott MI\, Xie Z\, Liu L\, Arunagiri A\, Wang Y\, Cazenave-Gass iot A\, Ghosh A\, von Meyenn F\, Kumarasamy S\, Najjar SM\, Jia S\, Wenk M R\, Traynor-Kaplan A\, Arvan P\, Barg S\, Bankaitis VA\, Poy MN. Restorati on of PITPNA in Type 2 diabetic human islets reverses pancreatic beta-cell dysfunction. Nat Commun. 2023 Jul 17\;14(1):4250. doi: 10.1038/s41467-023 -39978-1.\n\nKhan D\, Nile AH\, Tripathi A\, Bankaitis VA. 2021. Emerging Prospects for Combating Fungal Infections by Targeting Phosphatidylinosito l Transfer Proteins. Int J Mol Sci. 2021 Jun 23\;22(13):6754. doi: 10.3390 /ijms22136754.\n\nXie Z\, Bankaitis VA. 2022. Phosphatidylinositol transfe r protein/planar cell polarity axis regulates neocortical morphogenesis by supporting interkinetic nuclear migration. Cell Rep. 2022 May 31\;39(9):1 10869. doi: 10.1016/j.celrep.2022.110869.\n\n \;\n\nGeneral informatio n\n\n You can download and save all the spring 2025 FoS-seminars to your calendar from here: https://seafile.utu.fi/d/44a70f80ac1e46a9ad0a/\n Regi stration is not needed\, participation list is circulated in the audience\ n If you are a student and later wish to get a certificate of attendance from the Frontier of Science seminars\, print out the seminar diary and af ter the seminar ask the BioCity coordinator to sign it https://seafile.utu .fi/d/44a70f80ac1e46a9ad0a/\n Please note that any audio or video recordi ng of the seminars is strictly forbidden.\n Spring 2025 image credits to Teemu Tuominen: Close up photograph of soil bacteria Streptomyces colonies border.\n\n \;\n\n \; END:VEVENT BEGIN:VTIMEZONE TZID:Europe/Helsinki X-LIC-LOCATION:Europe/Helsinki BEGIN:STANDARD DTSTART:19690101T000000 TZOFFSETFROM:+0200 TZOFFSETTO:+0200 TZNAME:EET END:STANDARD END:VTIMEZONE END:VCALENDAR