BEGIN:VCALENDAR VERSION:2.0 PRODID:-//wp-events-plugin.com//7.2.3.1//EN TZID:Europe/Helsinki X-WR-TIMEZONE:Europe/Helsinki BEGIN:VEVENT UID:187007@bioscience.fi DTSTART;TZID=Europe/Helsinki:20260203T140000 DTEND;TZID=Europe/Helsinki:20260203T150000 DTSTAMP:20260109T061823Z URL:https://bioscience.fi/events/immunology-seminar-taija-makinen/ SUMMARY:Immunology Seminar\, Taija Mäkinen DESCRIPTION:\n\nImmunology Seminar Series\n\n \;\n\nFebruary 3rd at 14- 15 (Finland time)\n\nVirtual event\n\nFlyer\n\nTaija Mäkinen\, University of Helsinki: Lymphatic vasculature as a guardian of tissue homeostasis an d inflammation\n\nRegister for the Immunology Seminar Series email list to get calendar invitation to the online seminar: https://link.webropolsurve ys.com/S/D29C32AA6E8A2F7A\n\nHost: Professor Riitta Lahesmaa ( rilahes@utu .fi )\n\nImmunology seminar series is jointly organised by the Finnish Soc iety for Immunology\, InFLAMES Flagship and Turku Bioscience. For further information contact Anne Lahdenperä  ( ankahy@utu.fi ) or Riitta Lahesma a ( rilahes@utu.fi )\, University of Turku.\n\n \;\n\nTaija Mäkinen o btained her PhD from the University of Helsinki and completed postdoctoral training at the Max Planck Institute of Neurobiology in Martinsried\, Ger many. She previously served as a group leader at the Cancer Research UK Lo ndon Research Institute (now the Francis Crick Institute) and later as Pro fessor at Uppsala University. In 2024\, she returned to Finland and curren tly serves as Director of the Wihuri Research Institute and Professor at t he Faculty of Medicine\, University of Helsinki. Her research focuses on t he mechanisms regulating the lymphatic vascular system and its roles in he alth and disease.\n\nRecent selected publications:\nKraft M\, Schoofs H\, Petkova M\, Andrade J\, Grosso AR\, Benedito R\, De Roo AK\, Boon LM\, Vik kula M\, Kapp FG\, Hägerling R\, Potente M\, Mäkinen T. Angiopoietin-TIE 2 feedforward circuit promotes PIK3CA-driven venous malformations. Nat Car diovasc Res. 2025 Jul\;4(7):801-820. doi: 10.1038/s44161-025-00655-9.\n\nS choofs H\, Daubel N\, Schnabellehner S\, Grönloh MLB\, Palacios Martínez S\, Halme A\, Marks AM\, Jeansson M\, Barcos S\, Brakebusch C\, Benedito R\, Engelhardt B\, Vestweber D\, Gaengel K\, Linsenmeier F\, Schürmann S\ , Saharinen P\, van Buul JD\, Friedrich O\, Smith RS\, Majda M\, Mäkinen T. Dynamic cytoskeletal regulation of cell shape supports resilience of ly mphatic endothelium. Nature. 2025 May\;641(8062):465-475. doi: 10.1038/s41 586-025-08724-6.\n\nPetkova M\, Kraft M\, Stritt S\, Martinez-Corral I\, O rtsäter H\, Vanlandewijck M\, Jakic B\, Baselga E\, Castillo SD\, Grauper a M\, Betsholtz C\, Mäkinen T. Immune-interacting lymphatic endothelial s ubtype at capillary terminals drives lymphatic malformation. J Exp Med. 20 23 Apr 3\;220(4):e20220741. doi: 10.1084/jem.20220741.\n\nHernández Vásq uez MN\, Ulvmar MH\, González-Loyola A\, Kritikos I\, Sun Y\, He L\, Hali n C\, Petrova TV\, Mäkinen T. Transcription factor FOXP2 is a flow-induce d regulator of collecting lymphatic vessels. EMBO J. 2021 Jun 15\;40(12):e 107192. doi: 10.15252/embj.2020107192.\n\nMartinez-Corral I\, Zhang Y\, Pe tkova M\, Ortsäter H\, Sjöberg S\, Castillo SD\, Brouillard P\, Libbrech t L\, Saur D\, Graupera M\, Alitalo K\, Boon L\, Vikkula M\, Mäkinen T. B lockade of VEGF-C signaling inhibits lymphatic malformations driven by onc ogenic PIK3CA mutation. Nat Commun. 2020 Jun 8\;11(1):2869. doi: 10.1038/s 41467-020-16496-y.\n\n \; ATTACH;FMTTYPE=image/jpeg:https://bioscience.fi/wp-content/uploads/2025/12 /ISS-ThumbnailMakinen-03022026.png CATEGORIES:Turku Bioscience Events END:VEVENT BEGIN:VTIMEZONE TZID:Europe/Helsinki X-LIC-LOCATION:Europe/Helsinki BEGIN:STANDARD DTSTART:20251026T030000 TZOFFSETFROM:+0300 TZOFFSETTO:+0200 TZNAME:EET END:STANDARD END:VTIMEZONE END:VCALENDAR