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UID:186904@bioscience.fi
DTSTART;TZID=Europe/Helsinki:19700101T000000
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DTSTAMP:20260417T095048Z
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SUMMARY:Michael Courtney and Lili-Li receive $108\,867 grant from SynGAP Re
 search Fund (SRF) dba Cure SYNGAP1
DESCRIPTION:The SynGAP Research Fund 501(c)(3) dba Cure SYNGAP1 announced 
 a $108\,867 grant to Dr. Michael Courtney and Dr. Li-Li Li at the Tur
 ku Bioscience Centre\, University of Turku\, Finland\, to advance their re
 search on SYNGAP1 missense variants. Their project seeks to better under
 stand the functional impact of these mutations and explore drug repurposin
 g as a potential therapeutic approach.\n\nDr. Courtney’s team will use a
 dvanced phenotyping techniques to assess how SYNGAP1 missense variants i
 mpact the protein’s interaction with key neuronal components\, such as P
 SD95\, which is crucial for synaptic function. The project will also evalu
 ate repurposed drugs like Nortriptyline and Tanganil for their ability t
 o restore normal protein function. This comprehensive approach could lead 
 to new therapeutic strategies for patients with SYNGAP1-Related Disorders
  (SRD). &gt\;&gt\; Keep reading 
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