Turku Bioscience Centre – Header v3

Turku · Finland · Est. 1992

Turku
Bioscience
Centre

An advanced core facility and research centre jointly hosted by the University of Turku and Åbo Akademi University — where scientific infrastructure meets discovery.

Our Expertise. Your Discoveries.

Core Facilities

200+

Researchers

Host Universities

Research & Affiliated Groups

University of Turku

Åbo Akademi University

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NEWS

Researchers are investigating how snakes lost their limbs

Bioinformatics news October 8, 2026

Snakes have not always been legless, but have lost their limbs through evolution. Professor Laura Elo from the University of Turku is part of an…

NEWS

Frontiers of Science seminars are starting this week

Turku Bioscience News October 5, 2026

Autumn 2026 Frontiers of Science seminars start this week. Come for a coffee and sandwich at 11:45 to Presidentti auditorium, BioCity and listen to talks…

NEWS

Dissertation Defence: Eleftheria Maranou

Turku Bioscience News September 1, 2026

MSc Eleftheria Maranou, from affiliated MIORG group, succesfully defended the dissertation in Immunology titled “The Achilles’ heel of immune checkpoint blockade: Uncovering mechanisms of immune exclusion that drive…

NEWS

Researchers discover molecular mechanism that helps aggressive colorectal cancer to spread

Turku Bioscience News August 25, 2026

Researchers from the University of Turku in Finland, Turku Bioscience Centre and Gustave Roussy Institute in France have discovered a molecular mechanism that regulates whether…

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EVENT

Frontiers of Science: Prof. Miguel Soares

November 12, 2026 12:00 PM

12th November at 12:00 Onsite event in Presidentti auditorium, BioCity Autumn 2026 poster Prof. Miguel Soares, Gulbenkian Institute for Molecular Medicine, Portugal Metabolic adaptation as…

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EVENT

Frontiers of Science: Prof. Gwendalyn Randolph

November 19, 2026 12:00 PM

19th November at 12:00 Onsite event in Presidentti auditorium, BioCity Autumn 2026 poster Prof. Gwendalyn Randolph, WashU Medicine, USA The 3 L’s converge: Lymphoid tissue,…

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EVENT

CANCELLED Frontiers of Science: Prof. Maria Sibilia

November 26, 2026 12:00 PM

THIS SEMINAR IS CANCELLED and postponed to January 2027 Prof. Maria Sibilia, Medical University of Vienna, Austria Harnessing innate immunity to treat metastatic cancer: From…

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EVENT

Immunology Seminar Series: Raquel Bartolomé Casado

December 1, 2026 2:00 PM

Immunology Seminar Series December 1st at 14-15 (Finland time) Virtual event Flyer Raquel Bartolomé Casado, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, Norway: Studies…

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RECENT PUBLICATIONS | TURKU BIOSCIENCE CENTRE

Imaging cell architecture and dynamics – from images to insight

Francesca Bottanelli et al. J Cell Sci. 2026 Nov 1;139(21):jcs265433. doi: 10.1242/jcs.265433. Epub 2026 Nov 12. Published November 12, 2026

No abstract

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In Silico Assessment of SYNGAP1 Missense Variant Pathogenicity

Aliaa E Ali et al. Hum Mutat. 2026 Nov 8;2026:8234670. doi: 10.1155/humu/8234670. eCollection 2026. Published November 10, 2026

SynGAP, a critical regulator at the postsynaptic density, is associated with Alzheimer's disease, tumorigenesis, and most notably, SYNGAP1-related disorders (SRD), which manifests as autism, epilepsy,...

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B cell/adipocyte crosstalk amplifies MCP-1 secretion, M2-like macrophage accumulation, and polarization in gut-associated, inflamed adipose tissue

Marie Christine Goess et al. J Crohns Colitis. 2026 Nov 7;20(11):jjag182. doi: 10.1093/ecco-jcc/jjag182. Published November 7, 2026

CONCLUSION: B cell/adipocyte interactions in CD-associated inflamed adipose tissue increase MCP-1 and lactate, promoting recruitment and M2-like polarization of macrophages, likely amplifying local WAT inflammation.

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The Invisible Web: Linking Diet and Gut Microbiota Across Time and Space in Odonates

K M Kaunisto et al. Microb Ecol. 2026 Aug 4;89(1):203. doi: 10.1007/s00248-026-02850-y. Published November 6, 2026

The complex relationship between insects and their gut microbiota has become a central theme in host-microbe ecology, revealing profound effects on host fitness and interactions....

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Making smart microscopy deployable in imaging core facilities

Iván Hidalgo-Cenalmor et al. J Cell Sci. 2026 Nov 1;139(21):jcs265173. doi: 10.1242/jcs.265173. Epub 2026 Nov 5. Published November 5, 2026

Smart microscopy, in which real-time image analysis enables microscopes to adapt their acquisition dynamically, is becoming central to biological imaging. However, deploying such workflows in...

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Limitations of de novo peptide sequencing in resolving sequence ambiguity

Sam van Puyenbroeck et al. Nat Methods. 2026 Nov 3. doi: 10.1038/s41592-026-03301-9. Online ahead of print. Published November 3, 2026

De novo peptide sequencing enables peptide identification from fragmentation spectra without relying on sequence databases. However, incomplete spectra create ambiguity, making unambiguous identification challenging. Recent...

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Nanoparticle delivery systems for gene therapy of degenerative musculoskeletal diseases

Xiaofei Chen et al. J Orthop Translat. 2026 Oct 25;61:101241. doi: 10.1016/j.jot.2026.101241. eCollection 2026 Nov. Published October 31, 2026

Degenerative musculoskeletal diseases (DMDs) are a group of chronic conditions characterized by the progressive deterioration of tissue structure and function, primarily affecting the articular cartilage,...

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Comparative Pharmacological Effects of Tetracycline Derivatives on Osteoclast- and Osteoblast-Related Phenotypes and Skeletal Accumulation

Saeka Shimochi et al. Pharmaceuticals (Basel). 2026 Oct 10;19(10):1610. doi: 10.3390/ph19101610. Published October 27, 2026

Background/Objectives: Tetracycline (TC) derivatives possess biological activities beyond their antimicrobial effects and exhibit affinity for mineralized tissues. However, direct comparisons of clinically established TC derivatives...

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Maternal transmission and limited virulent phage replication shape early infant gut virome maturation

Kim Kreuze et al. Res Sq [Preprint]. 2026 Oct 5:rs.3.rs-11232673. doi: 10.21203/rs.3.rs-11232673/v1. Published October 25, 2026

Early-life gut microbiome dynamics are increasingly recognized as important determinants of microbiome maturation, yet the ecological dynamics of its associated bacteriophages remain poorly resolved. Here,...

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MOST RECENT PUBLICATIONS FROM USERS OF OUR CORE FACILITIES

Genes associated with immune response are upregulated in clinically healthy skin of patients with gliptin-associated bullous pemphigoid

N. Kokkonen et al. • Sep 1, 2026 • Journal of Investigative Dermatology

Core:Finnish Functional Genomics Centre

Emerging Microbial Lipid Shifts in a Multistage Simulated Gut Inoculated with Human Fecal Microbiota

I. Tamanna et al. • Aug 10, 2026 • Journal of Proteome Research

Abstract Food residues that bypass human digestion are further digested by gut microbes, leading to the production of diverse metabolites,...

Core:Metabolomics

Improving genotyped functional screening: A versatile closed-tube PCR for Illumina library generation reduces background sequences in multiplexed sequencing

S. Oksanen et al. • Jul 1, 2026 • SLAS Technology

Core:Finnish Functional Genomics Centre

Feasibility of multimodal metabolic analysis for detecting early changes in acute neuroinflammation

J. Grist et al. • May 4, 2026 • Journal of Neuroinflammation

Abstract Given the prevalence of metabolic perturbations in a variety of neurological and neurodegenerative diseases, understanding and monitoring brain metabolism...

Core:Metabolomics

Staphylococcus aureus Augments Epithelial Skin Barrier Damage Through T Cell Activation in Cutaneous T Cell Lymphoma

M. Gluud et al. • Mar 8, 2026 • Allergy

ABSTRACT Background Skin barrier dysfunction is central to inflammation and susceptibility to infection in atopic dermatitis (AD). Cutaneous T‐cell lymphoma...

Core:Cytometry Core