Turku Bioscience – Turku Centre for Biotechnology

Recent publications

Georgakis N. et al. Comparative structural and functional analysis of phi class glutathione transferases involved in multiple-herbicide resistance of grass weeds and crops. Plant Physiol Biochem. 2020 Feb 20;149:266-276. Pubmed→

Hui W. et al. Direct Activation of Protein Phosphatase 2A (PP2A) by Tricyclic Sulfonamides Ameliorates Alzheimer’s Disease Pathogenesis in Cell and Animal Models. Neurotherapeutics. 24/02/2020. Link to text→

Kauko O. et al. Phosphoproteome and drug response effects mediated by the three Protein Phosphatase 2A inhibitor proteins CIP2A, SET and PME-1. J Biol Chem. 2020 Feb 18. Pubmed→

Merisaari J. et al. Monotherapy efficacy of blood–brain barrier permeable small molecule reactivators of protein phosphatase 2A in glioblastoma. Brain Communications, Volume 2, Issue 1, 2020. Link to text→

Miner MW. et al. (2S, 4R)-4-[18F]Fluoroglutamine for In vivo PET Imaging of Glioma Xenografts in Mice: an Evaluation of Multiple Pharmacokinetic Models. Mol Imaging Biol. 2020 Jan 28. Pubmed→

Qiao X. et al. UBR5 is co-amplified with MYC in breast tumors and encodes an ubiquitin ligase that limits MYC-dependent apoptosis. Cancer Res. 2020 Feb 6. Pubmed→

Andersen L. et al. The Transcription Factor MAZR/PATZ1 Regulates the Development of FOXP3+ Regulatory T Cells. Cell Rep. 29:4447-4459.e6, 2019. Pubmed→

Joutsen J. et al. Heat Shock Factor 2 Protects against Proteotoxicity by Maintaining Cell-Cell Adhesion. Cell Rep. 2020 Jan 14;30(2):583-597.e6. Pubmed→

Mohsin I. et al. Crystal Structure of a GH3 β-Glucosidase from the Thermophilic Fungus Chaetomium thermophilum. Int J Mol Sci. 2019 Nov 27;20(23). Pubmed→

Mäkelä E et al. Arpp19 Promotes Myc and Cip2a Expression and Associates with Patient Relapse in Acute Myeloid Leukemia. Cancers (Basel). 2019 Nov 11;11(11). Pubmed→

Wang L et al. Effects of non-solvents and electrolytes on the formation and properties of cellulose I filaments. Sci Rep. 2019 Nov 13;9(1):16691 Pubmed→

Konki M. et al. Peripheral blood DNA methylation differences in twin pairs discordant for Alzheimer's disease. Clinical Epigenetics. 2019 Sep 2;11(1):130. Pubmed→

Papageorgiou AC. X-Ray Crystallography in Structure-Function Characterization of Therapeutic Enzymes. Adv Exp Med Biol. 2019;1148:81-103. Pubmed→

Shentu AP et al. Genistein Decreases APP/tau Phosphorylation and Ameliorates Aβ Over- production Through Inhibiting CIP2A.Curr Alzheimer Res. 2019 Aug 30. Pubmed→

Chronopoulou, E.G. et al. Structure-based design and application of an engineered glutathione transferase for the development of an optical biosensor for pesticides determination Biochim Biophys Acta. 2019;1863:565-576 Pubmed→

Theoharaki, C. et al. Delineation of the functional and structural properties of the glutathione transferase family from the plant pathogen Erwinia carotovora. Funct. Integr. Genomics. 2019;19:1-12 Pubmed→

Wang L et al. Conductive carbon microfibers derived from wet-spun lignin/nanocellulose hydrogels. ACS Sustain Chem Eng 7 (6). 2019; 6013-6022 Pubmed→

Manoharan GB et al. High-throughput amenable fluorescence-assays to screen for calmodulin-inhibitors. Anal Biochem. 2019 Feb 27. Pubmed→

Buehler U et al. Targeting prohibitins at the cell surface prevents Th17-mediated autoimmunity. EMBO J. 2018 Aug 15;37(16). Pubmed→

Sahlgren C et al. Tailored Approaches in Drug Development and Diagnostics: From Molecular Design to Biological Model Systems. Adv Healthc Mater. 2017 Nov;6(21). Pubmed→

Tripathi SK et al. Quantitative Proteomics Reveals the Dynamic Protein Landscape during Initiation of Human Th17 Cell Polarization. iScience. 2018 Dec 26;11:334-355. Pubmed→

Henriksson J et al. Genome-wide CRISPR Screens in T Helper Cells Reveal Pervasive Crosstalk between Activation and Differentiation. Cell. 2019 Jan 7, 2019. Pubmed→

Moreno-Layseca P et al. Integrin trafficking in cells and tissues.Nat Cell Biol. 2019 Jan 2. [Epub ahead of print] Review Pubmed→

Jacquemet G et al. (2019). Filopodome mapping identifies p130Cas as a mechanosensitive regulator of filopodia stability. Curr Biol 29, 1–15. Link to text→

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