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Turku Bioscience Centre

Turku Bioscience Centre

About us
State-of-the-art technology and research

State-of-the-art technology and research

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Biological and biomedical research

Biological and biomedical research

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Recent publications

Rytkönen KT. et al. Histone H3K4me3 breadth in hypoxia reveals endometrial core functions and stress adaptation linked to endometriosis. iScience. 2022 Apr 12;25(5):104235. Pubmed→
Välikangas T et al. Pancreas Whole Tissue Transcriptomics Highlights the Role of the Exocrine Pancreas in Patients With Recently Diagnosed Type 1 Diabetes. Front Endocrinol (Lausanne). 2022 Apr 13;13:861985.Pubmed→
Cvrljevic et al. Ovarian cancers with low CIP2A tumor expression constitute an APR-246 sensitive disease subtype. Molecular Cancer Therapeutics. 2022 Apr 1. Pubmed→
Starskaia I et al. Early DNA methylation changes in children developing beta cell autoimmunity at a young age. Diabetologia. 2022 Feb 10. PMID: 35142878 Pubmed→
Tomi Suomi et al. Type 1 Diabetes in Children With Genetic Risk May Be Predicted Very Early With a Blood miRNA. Diabetes Care. 2022 Feb 8 Pubmed→
Tanja Buchacher et al. Persistent coxsackievirus B1 infection triggers extensive changes in the transcriptome of human pancreatic ductal cells. iScience. 25(1): 103653, 2022. Link to page→
Mohd Moin Khan et al. PP2A and Its Inhibitors in Helper T-Cell Differentiation and Autoimmunity. Front. Immunol., 05 January, 2022. Link to page→
Ye Hong et al. PhosPiR: an automated phosphoproteomic pipeline in R. Briefings in Bioinformatics. 2021 Dec 8. Pubmed→
Partho S. et al. Quantitative genome-scale metabolic modeling of human CD4+ T cell differentiation reveals subset-specific regulation of glycosphingolipid pathways. Cell Reports. 2021 Nov. 9:37;6. Link to page→
Lamichhane S. et al. Exposure to per- and polyfluoroalkyl substances associates with an altered lipid composition of breast milk. Environ Int . 2021 Dec;157:106855. Pubmed→
Masoodi M et al. Metabolomics and lipidomics in NAFLD: biomarkers and non-invasive diagnostic tests. Nat Rev Gastroenterol Hepatol. 2021 Sep 10. Pubmed→
Sen P. et al. Exposure to environmental contaminants is associated with altered hepatic lipid metabolism in non-alcoholic fatty liver disease. J Hepatol . 2021 Oct 7;S0168-8278(21)02104-8.Pubmed→
Salomaa S et al. Conformational dynamics regulate SHANK3 actin and Rap1 binding. Current Biology. October 04, 2021. Link to Page→
Moreno-Layseca P et al. Cargo-specific recruitment in clathrin- and dynamin-independent endocytosis. Nat Cell Biol. 2021 Oct 6. Pubmed→
Miihkinen M et al. Myosin-X and talin modulate integrin activity at filopodia tips. Cell Rep. 2021 Sep 14;36(11):109716. Pubmed→
Al-Akhrass H et al. Sortilin-related receptor is a druggable therapeutic target in breast cancer. Mol Oncol. 2021 Sep 26. Pubmed→
Smolander J. et al. Evaluation of tools for identifying large copy number variations from ultra-low-coverage whole-genome sequencing data. BMC Genomics. 2021 May 17;22(1):357.Pubmed→
Lund RJ. et al. Placental DNA methylation marks are associated with maternal depressive symptoms during early pregnancy. Neurobiol Stress. 2021 Jul 31;15:100374.Pubmed→
Lamicchane S. et al. Exposure to per- and polyfluoroalkyl substances associates with an altered lipid composition of breast milk. Environ Int. 2021 Sep 6;157:106855. Pubmed→
Lund R et al. Placental DNA methylation marks are associated with maternal depressive symptoms during early pregnancy. Neurobiol Stress. 2021 Nov; 15: 100374. Pubmed→
Florian F et al. Hippocampal overexpression of NOS1AP promotes endophenotypes related to mental disorders. EBioMedicine. 2021 Sep; 71: 103565. Pubmed→
Faux T et al. Differential ATAC-seq and ChIP-seq peak detection using ROTS. NAR Genomics and Bioinformatics, Volume 3, Issue 3, September 2021. Link to page→
Felix I et al. Single-Cell Proteomics Reveals the Defined Heterogeneity of Resident Macrophages in White Adipose Tissue. Front. Immunol., 26 July 2021 Link to page→
Laine A. et al. CIP2A interacts with TopBP1 and drives basal-like breast cancer tumorigenesis. Cancer Res. 2021 Jun 18. Pubmed→
Neeraj P. et al. Circumventing Drug Treatment? Intrinsic Lethal Effects of Polyethyleneimine (PEI)-Functionalized Nanoparticles on Glioblastoma Cells Cultured in Stem Cell Conditions. Cancers (Basel). 2021 May 27;13(11):2631. Pubmed→
Gensollen T et al. Embryonic macrophages function during early life to determine invariant natural killer T cell levels at barrier surfaces. Nat Immunol. 2021; 22, 699–710. Pubmed→
Stephin J Vervoort et al. The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer. Cell. 2021 May 12. Online ahead of print. Pubmed→
Vihervaara A et al. Stress-induced transcriptional memory accelerates promoter-proximal pause release and decelerates termination over mitotic divisions. Mol Cell . 2021 Apr 15;81(8):1715-1731.e6. Pubmed→
Vainonen J et al. Druggable cancer phosphatases. Sci Transl Med. 2021 Apr 7. Pubmed→
Matila KE at al. A Three-feature Prediction Model for Metastasis-free Survival after Surgery of Localized Clear Cell Renal Cell Carcinoma. Scientific reports. 2021 Apr 21;11(1):8650. Pubmed→
Gulich AF et al. Complex Interplay Between MAZR and Runx3 Regulates the Generation of Cytotoxic T Lymphocyte and Memory T Cells. Front Immunol. 2021 Mar 17;12:535039. Pubmed→
Solveig KS et al. Crowdsourcing digital health measures to predict Parkinson’s disease severity: the Parkinson’s Disease Digital Biomarker DREAM Challenge. NPJ Digit Med. 2021 Mar 19;4(1):53. Pubmed→
Mäkelä E et al. Discovery of a Novel CIP2A Variant (NOCIVA) with clinical relevance in predicting TKI resistance in myeloid leukemias. Clin Cancer Res. 2021 Mar 5. Pubmed→
Venäläinen MS. Preoperative Risk Prediction Models for Short-Term Revision and Death After Total Hip Arthroplasty: Data from the Finnish Arthroplasty Register. JB JS Open Access. 2021 Jan 25;6(1):e20.00091. Pubmed→

News

  • 1900 news-image Turku Bioscience funding news
  • 1900 news-image BioCity Student Symposium – REGISTRATION IS NOW OPEN!
  • 1973 news-image BioCity Turku Collaborative Research Funding Call 2022
  • 1973 news-image New insights into regulation of immune response

Events

  • 1901 news-image 31st BioCity Symposium – SOLUTION IS IN IMMUNITY
  • 1901 news-image BioCity Student Symposium – STUDENTS ARE THE SOLUTION
  • 1901 news-image Immunology Seminar, Marko Salmi
  • 1901 news-image 10x Genomics User Meeting in Turku: The Power of Spatial and Single Cell Transcriptomics
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