32nd BioCity Symposium: Sculpting Tissues – cells, matrix and forces
The 32nd BioCity Symposium will explore the mechanisms regulating tissue architecture and homeostasis in biological organisms. This complex and dynamic “sculpting” process is carefully coordinated from the very beginning of life. Cells build tissues by proliferating, migrating, altering phenotype and generating a modifiable extracellular matrix (ECM).
In turn, the ECM’s biochemical and biomechanical properties determine cell behaviour and cell-cell crosstalk to control gene expression and cell state and the response to injury and insult (tissue repair, fibrosis, inflammation, cancer) and therapeutic targeting. Next year’s BioCity Symposium will focus on this reciprocal interplay between cells and their microenvironment to build healthy tissues, and how dysregulation ultimately leads to disease.
Christopher Chen, The Biological Design Center; Boston University; Harvard University, USA
Miki Ebisuya, European Molecular Biology Laboratory (EMBL) Barcelona, Spain
Peter Friedl, Radboud University Medical Center, Netherlands
Edouard Hannezo, Institute of Science and Technology Austria, Austria
Kairbaan Hodivala-Dilke, Barts Cancer Institute, Queen Mary University of London, UK
Daniel Krueger, Hubrecht Institute, Netherlands
Rachel Lennon, Wellcome Trust Centre for Cell-Matrix Research, UK
Alexandra Naba, University of Illinois at Chicago, USA
Michael Sixt, Institute of Science and Technology Austria, Austria
Fiona Watt, European Molecular Biology Organization (EMBO), Germany
Johanna Ivaska (organizing committee chair)