Publications

     

    Oliva-Olivera W, Castellano-Castillo D, von Meyenn F, Cardona F, Lönnberg T& Tinahones FJ:
    Human adipose tissue-derived stem cell paracrine networks vary according metabolic risk and after TNFα-induced death: an analysis at the single-cell level.
    Metabolism 2021; 14:154466. PMID: 33333081

     

    Mehtonen J, Teppo S, Lahnalampi M, Kokko A, Kaukonen R, Oksa L, Bouvy-Liivrand M, Malyukova A, Mäkinen A, Laukkanen S, Mäkinen PI, Rounioja S, Ruusuvuori P, Sangfelt O, Lund R, Lönnberg T, Lohi O & Heinäniemi M: Single cell characterization of B-lymphoid differentiation and leukemic cell states during chemotherapy in ETV6-RUNX1-positive pediatric leukemia identifies drug-targetable transcription factor activities.
    Genome Medicine 2020; 12(1):99. PMID: 33218352

     

    Kelkka T, Savola P, Bhattacharya D, Huuhtanen J, Lönnberg T, Kankainen M, Paalanen K, Tyster M, Lepistö M, Ellonen P, Smolander J, Eldfors S, Yadav B, Khan S, Koivuniemi R, Sjöwall C, Elo LL, Lähdesmäki H, Maeda Y, Nishikawa H, Leirisalo-Repo M, Sokka-Isler T, & Mustjoki S: Adult-Onset Anti-Citrullinated Peptide Antibody-Negative Destructive Rheumatoid Arthritis Is Characterized by a Disease-Specific CD8+ T Lymphocyte Signature.
    Frontiers in Immunology 2020; 11:578848. PMID: 33329548

     

    Depuydt MAC, Prange KHM, Slenders L, Örd T, Elbersen D, Boltjes A, de Jager SCA, Asselbergs FW, de Borst GJ, Aavik E, Lönnberg T, Lutgens E, Glass CK, Kaikkonen MU, Bot I, Slütter B, van der Laan SW, Yla-Herttuala S, Mokry M, Kuiper J, de Winther MPJ & Pasterkamp G: Microanatomy of the human atherosclerotic plaque by single-cell transcriptomics.
    Circulation Research 2020; 127(11):1437-1455. PMID: 32981416

     

    Kim D, Park G, Huuhtanen J, Lundgren S, Khajuria RK, Hurtado AM, Muñoz-Calleja C, Cardeñoso L, Gómez-García de Soria V, Chen-Liang TH, Eldfors S, Ellonen P, Hannula S, Bruck O, Kreutzman A, Salmenniemi U, Lönnberg T, Jerez A, Itälä-Remes M, Myllymäki M, Keränen MAI & Mustjoki S: Somatic Gain-of-Function mTOR mutation in Clonally Expanded T-lymphocytes Associated with Chronic Graft-Versus-Host Disease.
    Nature communications 2020; 11(1):2246. PMID: 32382059

     

    Takeda A, Hollmén M, Dermadi D, Pan J, Brulois KF, Kaukonen R, Lönnberg T, Boström P, Koskivuo I, Irjala H, Miyasaka M, Salmi M, Butcher EC & Jalkanen S: Single-Cell Survey of Human Lymphatics Unveils Marked Endothelial Cell Heterogeneity and Mechanisms of Homing for Neutrophils.
    Immunity 2019; 51(3):561-72. PMID: 31402260

     

    Jäppinen N, Félix I, Lokka E, Tyystjärvi S, Pynttäri A, Lahtela T, Gerke H, Elima K, Rantakari P, Salmi M: Fetal-derived macrophages dominate in adult mammary glands.
    Nature Communications 2019; 10(1):281.PMID:30655530

     

    Konki M, Malonzo M, Karlsson IK, Lindgren N, Ghimire B, Smolander J, Scheinin NM, Ollikainen M, Laiho A, Elo LL, Lönnberg T, Röyttä M, Pedersen NL, Kaprio J, Lähdesmäki H, Rinne J & Lund RJ: Peripheral Blood DNA Methylation Differences in Twin Pairs Discordant for Alzheimer’s Disease.
    Clinical Epigenetics 2019; 11(1),130. PMID: 31477183

     

    Kallionpää H, Somani J, Tuomela S, Ullah U, de Albuquerque R, Lönnberg T, Komsi E, Siljander H, Honkanen J, Härkönen T, Peet A, Tillmann T, Chandra V, Anagandula MK, Frisk G, Otonkoski T, Rasool O, Lund R, Lähdesmäki H, Knip M & Lahesmaa R: Early detection of peripheral blood cell signature in children developing beta-cell autoimmunity at a young age.
    Diabetes 2019; 68(10), 2024-2034. PMID 31311800

     

    Kolodziejczyk AA & Lönnberg T: Global and targeted approaches to single-cell transcriptome characterization.
    Briefings in Functional Genomics 2017; PMID:29028866

     

    Haque A, Engel J, Teichmann SA & Lönnberg T:
    A practical guide to single-cell RNA-sequencing for biomedical research and clinical applications. Genome Medicine 2017; 9(1):75. PMID:28821273