Publications – Turku Bioscience

Combined genetic and chemical screens indicate protective potential for EGFR inhibition to cardiomyocytes under hypoxia.
Heliste J, Jokilammi A, Vaparanta K, Paatero I, Elenius K.Sci Rep. 2021 Aug 17;11(1):16661. doi: 10.1038/s41598-021-96033-z.PMID: 34404849
Control of dynamic cell behaviors during angiogenesis and anastomosis by Rasip 1.
Lee M, Betz C, Yin J, Paatero I, Schellinx N, Carte AN, Wilson CW, Ye W, Affolter M, Belting HG. Development. 2021 Jun 22:dev.197509. doi: 10.1242/dev.197509. Online ahead of print. PMID: 34152400
Stromal interaction molecule 1 (STIM1) knock down attenuates invasion and proliferation and enhances the expression of thyroid-specific proteins in human follicular thyroid cancer cells. Asghar MY, Lassila T, Paatero I, Nguyen VD, Kronqvist P, Zhang J, Slita A, Löf C, Zhou Y, Rosenholm J, Törnquist K. Cell Mol Life Sci. 2021 Aug;78(15):5827-5846. doi: 10.1007/s00018-021-03880-0. Epub 2021 Jun 21. PMID: 34155535

A feed-forward loop between SorLA and HER3 determines heregulin response and neratinib resistance.
Al-Akhrass H, Conway JRW, Poulsen ASA, Paatero I, Kaivola J, Padzik A, Andersen OM, Ivaska J. Oncogene. 2021 Feb;40(7):1300-1317. doi: 10.1038/s41388-020-01604-5. Epub 2021 Jan 8. PMID: 33420373 Free PMC article.

Genetic and functional implications of an exonic TRIM55 variant in heart failure. Heliste, J., Chheda, H., Paatero, I., Salminen, T. A., Akimov, Y., Paavola, J., Elenius, K., & Aittokallio, T. (2020). Journal of molecular and cellular cardiology, 138, 222–233. https://doi.org/10.1016/j.yjmcc.2019.12.008

Helppokäyttöinen seeprakala tutkijan apuna. Paatero I and Paatero S. Solubiologi 2019, (2): 24-27.
GGA2 and RAB13 promote activity-dependent β1-integrin recycling. Sahgal P, Alanko J, Icha J, Paatero I, Hamidi H, Arjonen A, Pietilä M, Rokka A, Ivaska J. J Cell Sci. 2019 Jun 7;132(11). pii: jcs233387. doi: 10.1242/jcs.233387.PMID:31076515
ErbB4 tyrosine kinase inhibition impairs neuromuscular development in zebrafish embryos. Paatero I, Veikkolainen V, Mäenpää M, Schmelzer E, Belting HG, Pelliniemi LJ, Elenius K.Mol Biol Cell. 2019 Jan 15;30(2):209-218. doi: 10.1091/mbc.E18-07.

Paatero I, Sauteur L, Lee M, Lagendijk AK, Heutschi D, Wiesner C, Guzmán C, Bieli D, Hogan BM, Affolter M, Belting HG. Junction-based lamellipodia drive endothelial cell rearrangements in vivo via a VE-cadherin-F-actin based oscillatory cell-cell interaction. Nat Commun. 2018 Aug 31;9(1):3545. doi: 10.1038/s41467-018-05851-9. PMID:30171187 (PubMed)
Paatero, I., Alve, S., Gramolelli, S., Ivaska, J. and Ojala, P. M. (2018). Zebrafish Embryo Xenograft and Metastasis Assay. Bio-protocol 8(18): e3027. DOI: 10.21769/BioProtoc.3027.
Pekkonen P, Alve S, Balistreri G, Gramolelli S, Tatti-Bugaeva O, Paatero I, Niiranen O, Tuohinto K, Perälä N, Taiwo A, Zinovkina N, Repo P, Icay K, Ivaska J, Saharinen P, Hautaniemi S, Lehti K, Ojala PM. Lymphatic endothelium stimulates melanoma metastasis and invasion via MMP14-dependent Notch3 and β1-integrin activation. Elife. 2018 May 1;7. pii: e32490. doi: 10.7554/eLife.32490. PMID:29712618 (PubMed)

Paatero I, Casals E, Niemi R, Özliseli E, Rosenholm JM, Sahlgren C. Analyses in zebrafish embryos reveal that nanotoxicity profiles are dependent on surface-functionalization controlled penetrance of biological membranes.Sci Rep. 2017 Aug 21;7(1):8423. doi: 10.1038/s41598-017-09312-z. PMID: 28827674 (PubMed)
Jacquemet G, Paatero I, Carisey AF, Padzik A, Orange JS, Hamidi H, Ivaska J. FiloQuant reveals increased filopodia density during breast cancer progression. J Cell Biol. 2017 Oct 2;216(10):3387-3403. doi: 10.1083/jcb.201704045. Epub 2017 Aug 1. PMID: 28765364 (PubMed)