Ongoing projects
Organisation of Signalling Pathways – Roles in Disorders of the Nervous System
- NOS1AP/CAPON: mechanisms of action on NMDA receptor signalling through nNOS (review)
- NOS1AP/CAPON : contribution to diseases and disorders (hypoxia-ischaemia, neuropathic pain, schizophrenia, neurodegenerative disorders)
An Optogenetic and Optopharmacological toolbox for precise control of cell signalling pathways
- OptoJNKi and Optop38i, new tools for precise spatiotemporal control of JNK and p38 pathways (see www.nature.com/articles/ncomms15017, press release, plasmids)
- A novel design strategy for rapid generation of optically regulated inhibitors – extending the toolbox
Development of High-Content Analysis and High-Throughput Microscopy tools and methods
- Applications for signalling pathways and neuroscience
- Workshops: check back later for the next workshop (last workshop was 19-20 June 2017)
- Provision of high-throughput infrastructure and services for biological research, chemical biology and early-stage drug discovery (Screening unit)