Selected Publications using the services of the Turku Proteomics Facility

2024

Landoni, J.C., Erkul, S., Laalo, T., Goffart, S., Kivelä, R., Skube, K., Nieminen, A.I., Wickström, S.A., Stewart, J., Suomalainen, A. Overactive mitochondrial DNA replication disrupts perinatal cardiac maturation. Nature Communications 15, 8066 (2024). https://doi.org/10.1038/s41467-024-52164-1. PMID: 39277581

Andrabi, S.B.A., Kalim, U.U., Palani, S., Khan, M.M., Khan, M.H., Fagersund, J., Orpana, J., Paulin, N., Batkulwar, K., Junttila, S., Buchacher, T., Grönroos, T., Toikka, L., Ammunet, T., Sen, P., Orešič, M., Kumpulainen, V., Tuomisto, J.E.E., Sinha, R., Marson, A., Rasool, O., Elo, L.L., Lahesmaa, R. Long noncoding RNA LIRIL2R modulates FOXP3 levels and suppressive function of human CD4+ regulatory T cells by regulating IL2RA, Proc. Natl. Acad. Sci. U.S.A. 121, 23, e2315363121 (2024), https://doi.org/10.1073/pnas.2315363121. PMID: 38805281

Vaparanta, K., Merilahti, J., Ojala, V.K., Elenius, K. De Novo Multi-Omics Pathway Analysis Designed for Prior Data Independent Inference of Cell Signaling Pathways. Molecular & Cellular Proteomics 23, 7 (2024) doi: https://doi.org/10.1016/j.mcpro.2024.100780. PMID: 38873899 

2023

Pavic, K., Gupta, N., Omella, J.D., Derua, R., Aakula, A., Huhtaniemi, R., Määttä, J.A., Höfflin, N., Okkeri, J., Wang, Z., Kauko, O., Varjus, R., Honkanen, H., Abankwa, D., Köhn, M., Hytönen, V.P., Xu, W., Nilsson, J., Page, R., Janssens V., Leitner, A., Westermarck, J. Structural mechanism for inhibition of PP2A-B56α and oncogenicity by CIP2A. Nature Communications 14, 1143 (2023). https://doi.org/10.1038/s41467-023-36693-9. PMID: 36854761

Vaparanta, K., Jokilammi, A., Paatero, I., Merilahti, J.A.M., Heliste, J., Hemanthakumar, K.A., Kivelä, R., Alitalo, K., Taimen, P., Elenius K. STAT5b is a key effector of NRG-1/ERBB4-mediated myocardial growth. EMBO Reports 24, e56689 (2023). https://doi.org/10.15252/embr.202256689. PMID: 37009825

Moulder, R., Välikangas, T., Hirvonen, M.K., Suomi, T., Brorsson, C.A., Lietzén, N., Bruggraber, S.F.A., Overbergh, L., Dunger, D.B., Peakman, M., Chmura, P.J., Brunak, S., Schulte, A.M., Mathieu C., Knip, M., Elo, L.L., Lahesmaa, R. Targeted serum proteomics of longitudinal samples from newly diagnosed youth with type 1 diabetes distinguishes markers of disease and C-peptide trajectory. Diabetologia (2023). https://doi.org/10.1007/s00125-023-05974-9

2022

Vaparanta, K., Jokilammi, A., Tamirat, M., Merilahti, J.A.M., Salokas K., Varjosalo, M., Ivaska, J., Johnson, M.S., Elenius, K. An extracellular receptor tyrosine kinase motif orchestrating intracellular STAT activation. Nature Communications 13, 6953 (2022). https://doi.org/10.1038/s41467-022-34539-4. PMID: 36376313

Ankitha, S., Tripathi, S.K., Junttila, S., Buchacher, T., Biradar, R., Bhosale, S.D., Envall, T., Laiho, A., Moulder, R., Rasool, O., Galande, S., Elo, L.L., Lahesmaa, R. A systematic comparison of FOSL1, FOSL2 and BATF-mediated transcriptional regulation during early human Th17 differentiation, Nucleic Acids Research 50, 9, (2022), 4938–4958, https://doi.org/10.1093/nar/gkac256. PMID: 35511484

Gerotto, C., Trotta, A., Bajwa, A.A., Morosinotto, T., Aro, E-A. Role of serine/threonine protein kinase STN7 in the formation of two distinct photosystem I supercomplexes in Physcomitrium patens, Plant Physiology, 190, 1, (2022), 698–713, https://doi.org/10.1093/plphys/kiac294. PMID: 35736511