Moriah M Mitchell et al.Nat Commun. 2026 Jun 22. doi: 10.1038/s41467-026-74680-y. Online ahead of print.Published June 22, 2026
The human antiviral antibody reactome provides a cumulative molecular record of immune exposures. Using high-resolution VirScan profiling, we compared epitope-level antibody responses across early childhood... Read more
Yifeng Fang et al.Biomaterials. 2026 Jun 13;335:124373. doi: 10.1016/j.biomaterials.2026.124373. Online ahead of print.Published June 18, 2026
Despite advances in oncology, the dual challenge of achieving precise tumor-targeted therapy while simultaneously activating antitumor immunity remains a major clinical barrier. In this study,... Read more
Akseli Kehusmaa et al.J Pathol. 2026 Jun 18. doi: 10.1002/path.70087. Online ahead of print.Published June 18, 2026
Tumor border configuration influences colorectal cancer (CRC) prognosis, yet its molecular determinants remain unclear and existing assessment criteria have faced challenges with reproducibility. We introduce... Read more
Tuomas Sipilä et al.J Clin Invest. 2026 Jun 15;136(12):e190552. doi: 10.1172/JCI190552. eCollection 2026 Jun 15.Published June 15, 2026
The blood and lymphatic vascular systems are regulated by angiopoietin (ANGPT) growth factors, which signal via endothelial TIE receptor tyrosine kinases and integrins. However, mechanistic... Read more
Linda Nissi et al.Am J Otolaryngol. 2026 Jun 10;47(4):104869. doi: 10.1016/j.amjoto.2026.104869. Online ahead of print.Published June 12, 2026
CONCLUSION: DOI was not a prognostic factor in p16-positive T1-2 OPSCC. Nevertheless, DOI may hold prognostic relevance for p16-negative disease. The patterns of local invasion... Read more
João Marcos G Barbosa et al.Environ Int. 2026 May 29;213:110337. doi: 10.1016/j.envint.2026.110337. Online ahead of print.Published May 30, 2026
Per- and polyfluoroalkyl substances (PFAS) are highly persistent environmental pollutants that bioaccumulate in living organisms and are increasingly implicated in metabolic dysfunction-associated steatotic liver disease... Read more
Angelica P Ahrens et al.mSystems. 2026 May 28:e0142425. doi: 10.1128/msystems.01424-25. Online ahead of print.Published May 28, 2026
Childhood obesity is rising globally. Yet, few studies have examined the microbiome and proteome in early childhood in relation to this outcome, and most are... Read more
Tomi Suomi et al.Bioinformatics. 2026 May 22:btag335. doi: 10.1093/bioinformatics/btag335. Online ahead of print.Published May 24, 2026
SUMMARY: Recently, Anwar et al. introduced a method combining the ROTS reproducibility optimisation procedure with empirical Bayes variance estimation from limma. Here, we clarify several... Read more
Wei Ba et al.Curr Biol. 2026 May 19:S0960-9822(26)00529-4. doi: 10.1016/j.cub.2026.04.059. Online ahead of print.Published May 20, 2026
How the brain compensates for sleep deprivation (SD) by generating recovery sleep (RS) is not understood. Using Ca²⁺ photometry, we identified a WAKE/rapid eye movement... Read more
Markus Lindén et al.Protein Sci. 2026 Jun;35(6):e70621. doi: 10.1002/pro.70621.Published May 18, 2026
Biomedical studies increasingly incorporate longitudinal data, enabling us to track individual disease processes over time at the molecular level, and to discover associations of the... Read more
Venla Huovinen et al.Dev Psychopathol. 2026 May 8:1-15. doi: 10.1017/S0954579426101527. Online ahead of print.Published May 8, 2026
CONCLUSIONS: Alpha diversity in infancy was negatively associated with preschool EF. Additionally, EFs differed between microbial groups based on dominant genera. Bacterial genera abundances were... Read more
Mona M Wang et al.Commun Biol. 2026 May 5. doi: 10.1038/s42003-026-10118-x. Online ahead of print.Published May 5, 2026
BAP1-deficient melanocytic tumors exhibit strong immunosuppressive features and poor prognosis. Currently, no immune-competent preclinical models exist to study their tumor-immune interactions or test new immunotherapies.... Read more
