Turku Bioscience Centre

bioinformatics discoveries research results

New computational tool helps scientists interpret complex single-cell data

November 17, 2025

Researchers from Laura Elo's group, have developed a new computational method to interpret complex single-cell data. The method helps researchers identify and group cell types across samples. "We were inspired by the process of assembling Read more

Carlos Rogério Figueiredo received the Young Investigator Award

November 4, 2025

Carlos Rogério Figueiredo has received the Young Investigator Award from the Scandinavian Society for Immunology. The award is given for high-quality immunological research and promotion of the field of immunology. Figueiredo was announced as the Read more

Awards

Participate to Open Hardware Workshop, sign up now!

November 3, 2025

Access to research hardware remains a global challenge and it impacts also researchers in high-income countries. The availability of hardware may be limited due to lack of funding, slow acquisition processes, geographic distance, and many Read more

academy of finland academy professor grants

The Academy of Finland granted Johanna Ivaska €2,400,000 in funding for an Academy Professor position

October 30, 2025

The Academy of Finland granted our Group Leader, Professor Johanna Ivaska €2,400,000 in funding for an Academy Professor position to support research investigating how the stiffness and composition of the tissue surrounding a cancer tumor Read more

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AI2Med Conference

November 25, 2025

AI2Med Conference

November 25, 2025

25th–26th November Onsite event in Presidentti auditorium, BioCity Flyer AI2Med is Turku’s dedicated event bringing together AI researchers and medical professionals. This two-day event focuses on the growing need for collaboration between computational scientists and Event details

Bioscience Open Hardware Workshop Seminar Day

December 1, 2025

Bioscience Open Hardware Workshop Seminar Day

December 1, 2025

1st December at 08:30-15:00 Onsite event place TBA Access to research hardware remains a global challenge and it impacts also researchers in high-income countries. The availability of hardware may be limited due to lack of Event details

MSc Thesis Project Expo 2025

December 3, 2025

MSc Thesis Project Expo 2025

December 3, 2025

3rd December at 09:00-11:00 Onsite event in Tiedonkolu, Medisiina D Are you a biosciences MSc student wondering where to find a lab to do your MSc thesis? Are you running a life science lab Event details

Frontiers of Science: Prof. Sara Wickström

December 4, 2025

Frontiers of Science: Prof. Sara Wickström

December 4, 2025

4th December at 12:00 Onsite event in Presidentti auditorium, BioCity Autumn 2025 program Prof. Sara Wickström, University of Helsinki, Finland Mechanical regulation of cell states Host: Jenny Pessa (jenny.pessa@abo.fi) Coffee and sandwich served at 11:45, Event details

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10

Core Facilities

Providing cutting-edge biomedical research services through advanced technologies and expert support.

17 + 11

Research & Affiliate Groups

Collaborating across disciplines to drive innovative solutions and breakthrough discoveries.

100+

Publications

Annual publications showcasing impactful scientific contributions in leading international journals.

PUBLICATION

Hepatic zonation determines tumorigenic potential of mutant β-catenin

Alexander Raven et al.

Nature. 2025 Nov 19. doi: 10.1038/s41586-025-09733-1. Online ahead of print.

Published on November 19, 2025

Oncogenic mutations in phenotypically normal tissue are common across adult organs^(1,2). This suggests that multiple events need to converge to drive tumorigenesis and that many Read more

PUBLICATION

Breast cancer remodels lymphatics in sentinel lymph nodes

Dominik Eichin et al.

Nat Commun. 2025 Nov 17;16(1):10056. doi: 10.1038/s41467-025-64981-z.

Published on November 17, 2025

Cancer metastasis to sentinel lymph nodes (LNs) is often the first marker of potential disease progression. Although it is recognized that tumor-induced lymphangiogenesis facilitates metastasis Read more

PUBLICATION

LINC01871 is exclusively expressed in T and NK cells and is highly induced upon CD4+ T cell activation

Ubaid Ullah Kalim et al.

iScience. 2025 Oct 15;28(11):113779. doi: 10.1016/j.isci.2025.113779. eCollection 2025 Nov 21.

Published on November 17, 2025

Long intergenic noncoding RNAs (lincRNAs) regulate biological processes in health and disease. Recent findings highlight the importance of lincRNAs in regulating T cell development and Read more

PUBLICATION

Coralysis enables sensitive identification of imbalanced cell types and states in single-cell data via multi-level integration

António G G Sousa et al.

Nucleic Acids Res. 2025 Nov 13;53(21):gkaf1128. doi: 10.1093/nar/gkaf1128.

Published on November 16, 2025

Complex single-cell analyses now routinely integrate multiple datasets, followed by cell-type annotation and differential expression analysis. Current state-of-the-art integration methods often struggle with imbalanced cell Read more

PUBLICATION

Single-cell to pre-clinical evaluation of Trem2, Folr2, and Slc7a7 as macrophage-associated biomarkers for atherosclerosis

Tiit Örd et al.

Cardiovasc Res. 2025 Nov 7:cvaf210. doi: 10.1093/cvr/cvaf210. Online ahead of print.

Published on November 9, 2025

CONCLUSIONS: Our findings provide novel insights into macrophage-specific gene programs during atherosclerosis progression and identify a set of promising biomarkers that can serve as a Read more

PUBLICATION

Drug target proteome profiling identifies HES1-driven mitotic catastrophe in ovarian serous carcinoma

Jie Bao et al.

Biomed Pharmacother. 2025 Nov 6;193:118716. doi: 10.1016/j.biopha.2025.118716. Online ahead of print.

Published on November 7, 2025

Ovarian high-grade serous cancer (HGSC) is the most aggressive ovarian cancer subtype with limited treatment options. We identify the PDPK1 inhibitor BX-912 as a promising Read more

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Multimedia Science Communication

The Role of Multimedia in Science

November 12, 2025

Have you ever been to a talk or lecture and felt bored? The problem is rarely the science itself, but how it is presented. Cluttered slides, tiny text, odd color combinations, flickering screens, bad audio, Read more

experience TET harjoittelu training

Career exploration week at the University of Turku: Surprises, Science & Early Morning Struggles

October 9, 2025

This was my first TET week and I got to go to the University of Turku. There has been all kinds of interesting and exciting stuff here, but the best thing is the university staff—many Read more

Turning KRAS Against Itself: A New Way to Kill Cancer Cells

September 9, 2025

We are excited to share the story behind our recent work, published in a scientific journal in 2024, where we uncovered a surprising vulnerability in some of the most aggressive cancers. Our work was one Read more