See the Publications on Pubmed

Andrabi SBA, Kalim UU, Palani S, Khan MM, Khan MH, Fagersund J, Orpana J, Paulin N, Batkulwar K, Junttila S, Buchacher T, Grönroos T, Toikka L, Ammunet T, Sen P, Orešič M, Kumpulainen V, Tuomisto JEE, Sinha R, Marson A, Rasool O, Elo LL, Lahesmaa R. Long Noncoding RNA LIRIL2R Modulates FOXP3 Levels and Suppressive Function of Human CD4+ Regulatory T Cells by Regulating IL2RA. Proc Natl Acad Sci U S A. 121:e2315363121, 2024. doi: 10.1073/pnas.2315363121.

Kalim UU, Biradar R, Junttila S, Khan MM, Tripathi S, Khan MH, Smolander J, Kanduri K, Envall T, Laiho A, Marson A, Rasool O, Elo LL, Lahesmaa R. A proximal enhancer regulates RORA expression during early human Th17 cell differentiation. Clin Immunol. 264:110261, 2024. doi: 10.1016/j.clim.2024.110261.

Starskaia I, Valta M, Pietilä S, Suomi T, Pahkuri S, Kalim UU, Rasool O, Rydgren E, Hyöty H, Knip M, Veijola R, Ilonen J, Toppari J, Lempainen J, Elo LL, Lahesmaa R. Distinct cellular immune responses in children en route to type 1 diabetes with different first appearing autoantibodies. Nat Commun. 15:3810, 2024. doi: 10.1038/s41467-024-47918-w.

Buchacher T, Shetty A, Koskela SA, Smolander J, Kaukonen R, Sousa AGG, Junttila S, Laiho A, Rundquist O, Lönnberg T, Marson A, Rasool O, Elo LL, Lahesmaa R. PIM kinases regulate early human Th17 cell differentiation. Cell Rep. 42:113469, 2023. doi: 10.1016/j.celrep.2023.113469.

Andrabi SBA, Batkulwar K, Bhosale SD, Moulder R, Khan MH, Buchacher T, Khan MM, Arnkil I, Rasool O, Marson A, Kalim UU, Lahesmaa R. HIC1 interacts with FOXP3 multi protein complex: Novel pleiotropic mechanisms to regulate human regulatory T cell differentiation and function. Immunol Lett. 263:123-132, 2023. doi: 10.1016/j.imlet.2023.09.001.

Hirvonen MK, Lietzén N, Moulder R, Bhosale SD, Koskenniemi J, Vähä-Mäkilä M, Nurmio M, Orešič M, Ilonen J, Toppari J, Veijola R, Hyöty H, Lähdesmäki H, Knip M, Cheng L, Lahesmaa R. Serum APOC1 levels are decreased in young autoantibody positive children who rapidly progress to type 1 diabetes. Sci Rep. 13:15941, 2023. doi: 10.1038/s41598-023-43039-4.

Moulder R, Välikangas T, Hirvonen MK, Suomi T, Brorsson CA, Lietzén N, Bruggraber SFA, Overbergh L, Dunger DB, Peakman M, Chmura PJ, Brunak S, Schulte AM, Mathieu C, Knip M, Elo LL, Lahesmaa R; INNODIA consortium. Targeted serum proteomics of longitudinal samples from newly diagnosed youth with type 1 diabetes distinguishes markers of disease and C-peptide trajectory. Diabetologia. 66:1983-1996, 2023. doi: 10.1007/s00125-023-05974-9.

Suomi T, Starskaia I, Kalim UU, Rasool O, Jaakkola MK, Grönroos T, Välikangas T, Brorsson C, Mazzoni G, Bruggraber S, Overbergh L, Dunger D, Peakman M, Chmura P, Brunak S, Schulte AM, Mathieu C, Knip M, Lahesmaa R, Elo LL; INNODIA Consortium. Gene expression signature predicts rate of type 1 diabetes progression. EBioMedicine. 92:104625,2023. doi: 10.1016/j.ebiom.2023.104625.

Shetty A, Tripathi SK, Junttila S, Buchacher T, Biradar R, Bhosale SD, Envall T, Laiho A, Moulder R, Rasool O, Galande S, Elo LL, Lahesmaa R. A systematic comparison of FOSL1, FOSL2 and BATF-mediated transcriptional regulation during early human Th17 differentiation. Nucleic Acids Research. 50:4938-4958. 2022. doi: 10.1093/nar/gkac256.

Khan MM, Meraj Hasan Khan MH, Kalim UU, Khan S, Junttila S, Paulin N, Kong L, Rasool O, Elo LL, Lahesmaa R. Long Intergenic Noncoding RNA MIAT as a Regulator of Human Th17 Cell Differentiation. Front. Immunol. 13:856762, 2022. doi: 10.3389/fimmu.2022.856762.

Oras A, Kallionpää H, Suomi T, S, Laiho A, Elo LL, Knip M, Lahesmaa R, Aints A, Uibo R, DIABIMMUNE Study Group. Profiling of peripheral blood B-cell transcriptome in children who developed coeliac disease in a prospective study. Heliyon 9: e13147, 2023. doi: 10.1016/j.heliyon.2023.e13147.

Fortino V, Kinaret PAS, Fratello M, Serra A, Saarimäki LA, Gallud A, Gupta G, Vales G, Correia M, Rasool O, Ytterberg J, Monopoli M, Skoog T, Ritchie P, Moya S, Vázquez-Campos S, Handy R, Grafström R, Tran L, Zubarev R, Lahesmaa R, Dawson K, Loeschner K, Larsen EH, Krombach F, Norppa H, Kere J, Savolainen K, Alenius H, Fadeel B, Greco D. Biomarkers of nanomaterials hazard from multi-layer data. Nat Commun. 13: 3798, 2022. doi: 10.1038/s41467-022-31609-5.

Välikangas T, Lietzén N, Jaakkola MK, Krogvold L, Eike MC, Kallionpää H, Tuomela S, Mathews C, Gerling IC, Oikarinen S, Hyöty H, Dahl-Jorgensen K, Elo LL, Lahesmaa R. Front Endocrinol (Lausanne). Pancreas Whole Tissue Transcriptomics Highlights the Role of the Exocrine Pancreas in Patients With Recently Diagnosed Type 1 Diabetes. Front Endocrinol (Lausanne) 13:861985, 2022. doi: 10.3389/fendo.2022.861985.

Laajala E, Kalim UU, Grönroos T, Rasool O, Halla-aho V, Konki M, Kattelus R, Mykkänen J, Nurmio M, Vähä-Mäkilä M, Kallionpää H, Lietzén N, Ghimire BR, Laiho A, Hyöty H, Elo LL, Ilonen J, Knip M, Lund RJ, Orešič M, Veijola R, Lähdesmäki H, Toppari J, Lahesmaa R. Umbilical Cord Blood DNA Methylation in Children Who Later Develop Type 1 Diabetes. Diabetologia. 65: 1534–1540, 2022. doi: 10.1007/s00125-022-05726-1.

Laajala E, Halla-Aho V, Grönroos T, Kalim UU, Vähä-Mäkilä M, Nurmio M, Kallionpää H, Lietzén N, Mykkänen J, Rasool O, Toppari J, Orešič M, Knip M, Lund R, Lahesmaa R, Lähdesmäki H. Permutation-based significance analysis reduces the type 1 error rate in bisulfite sequencing data analysis of human umbilical cord blood samples. Epigenetics. Mar 4:1-20, 2022. doi: 10.1080/15592294.2022.2044127.