Turku Bioscience Centre

Turku Bioscience Centre is an advanced core facility and research centre hosted jointly by University of Turku and Åbo Akademi University.

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News

New diagnostic breakthrough predicts which head and neck cancer patients can be cured with surgery alone

July 23, 2025

Researchers from the University of Turku and Turku University Hospital, Finland, led by Docent Sami Ventelä and Professor Jukka Westermarck, have identified a novel diagnostic tool that can revolutionize the treatment guidance of head and neck squamous cell Read more

Professor Riitta Lahesmaa has been elected as a member of EMBO

July 1, 2025

The European Molecular Biology Organization (EMBO) has selected Professor Riitta Lahesmaa from the University of Turku as its member. The organization annually elects new members based on scientific merit. EMBO is an international organization that Read more

Research Council of Finland Awards Funding to Turku Bioscience Researchers

June 24, 2025

New Research Council of Finland funding was granted to Turku Bioscience researchers: Riitta Lahesmaa (Turku Bioscience Centre, InFlames Flagship): New regulators of the human immune response, €599,985 Affiliated group leader:Pieta Mattila (Department of Biomedicine, InFlames Read more

funding news Research Council of Finland suomen akatemia

Guillaume Jacquemet appointed to K. Albin Johansson Research Professorship

June 19, 2025

Associate Professor, InFLAMES PI Guillaume Jacquemet (Åbo Akademi University) and our affiliated Group Leader has been appointed to a prestigious five-year K. Albin Johansson Research Professorship funded by the K. Albin Johansson Foundation and the Read more

Meng Wang (Mona) Successfully Defended PhD on Novel Immune and Genetic Drivers of Melanoma

June 16, 2025

Meng Wang from our affiliated Figueiredo Lab (MIORG) successfully defended her PhD thesis “Novel Immune and Genetic Drivers of Melanoma: Integrative and New Preclinical Models to Uncover the Impact of New Chromosomal and Transcriptomic Changes Read more

cancer Melanoma

Researchers elucidate the role of jaundice during malaria as a metabolic response against Plasmodium infection

June 13, 2025

Researchers from the Turku Bioscience Centre at the University of Turku in Finland collaborated with a leading malaria research group at Gulbenkian Institute of Molecular Medicine (GIMM) in Portugal to elucidate a metabolite-based defense mechanism Read more

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Events

The Sugarscience Th1nk Tank: Proteomics insights into type 1 diabetes development

August 12, 2025

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August 12, 2025 @ 12:00 am - 1:00 pm -

34th BioCity Symposium: Transforming drug development for tomorrow

August 28, 2025

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August 28, 2025 - August 29, 2025 @ 8:30 am - 5:00 pm - The 34th BioCity Symposium focuses on drug development across a range of Event details

Frontiers of Science: Prof. Hiroki Ueda

September 18, 2025

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18th September at 12:00 Onsite event in Presidentti auditorium, BioCity Autumn 2025 program Prof. Hiroki Ueda, University of Tokyo, Japan Why do we sleep? The role of calcium and phosphorylation in sleep Host: Diana Lehotina Event details

Frontiers of Science: Prof. Olli Kallioniemi

October 2, 2025

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2nd October at 12:00 Onsite event in Presidentti auditorium, BioCity Autumn 2025 program Prof. Olli Kallioniemi, FIMM, HiLife, University of Helsinki, Finland Technology-, data- and AI-driven translational cancer research Host: Klaus Elenius (klaele@utu.fi) Coffee and Event details

Frontiers of Science: Prof. Pere Roca-Cusachs

October 9, 2025

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9th October at 12:00 Onsite event in Presidentti auditorium, BioCity Autumn 2025 program Prof. Pere Roca-Cusachs, University of Barcelona, Spain Understanding and controlling mechanotransduction, from integrins to the nucleus Host: Johanna Ivaska (johanna.ivaska@utu.fi) Coffee and Event details

BioCity Turku Guest Seminar: Prof. Mark Daly

October 21, 2025

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21st October at 12:00-13:00 Onsite event in Presidentti auditorium, BioCity Prof. Mark Daly, Massachusetts General Hospital; Harvard Medical School, USA Title TBA Host: Teemu Niiranen (tejuni@uti.fi) Mark Daly is the founding Chief of the Event details

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Recent Publications

Phosphoproteomic analysis reveals the diversity of signaling behind ErbB-inhibitor-induced phenotypes

Katri Vaparanta et al.

FEBS J. 2025 Jul 24. doi: 10.1111/febs.70197. Online ahead of print.

Published on July 24, 2025

The impact of kinase inhibitors on the phosphoproteome has been rarely investigated at a whole-organism level. Here, we performed a phosphoproteomic analysis in embryonic zebrafish Read more

Does cannabidiol reduce the adverse effects of cannabis in schizophrenia? A randomised, double-blind, cross-over trial

Edward Chesney et al.

Neuropsychopharmacology. 2025 Jul 24. doi: 10.1038/s41386-025-02175-3. Online ahead of print.

Published on July 23, 2025

In patients with schizophrenia, cannabis use exacerbates symptoms and can lead to a relapse of psychosis. Some experimental studies in healthy volunteers suggest that pre-treatment Read more

Correction: The PP2A regulator IER5L supports prostate cancer progression

Jana R Crespo et al.

Cell Death Dis. 2025 Jul 22;16(1):545. doi: 10.1038/s41419-025-07802-x.

Published on July 22, 2025

No abstract

LIMA1-alpha staining predicts curative intent surgery response in HPV negative head and neck cancer

Xi Qiao et al.

EMBO Mol Med. 2025 Jul 17. doi: 10.1038/s44321-025-00266-8. Online ahead of print.

Published on July 17, 2025

In many solid cancer types, surgery alone could be a sufficient first therapy option for a significant number of cancer patients. However, there are currently Read more

EPLINα controls integrin recycling from Rab21 endosomes to drive breast cancer cell migration

Niklas Z Jäntti et al.

Dev Cell. 2025 Jul 9:S1534-5807(25)00403-4. doi: 10.1016/j.devcel.2025.06.025. Online ahead of print.

Published on July 16, 2025

Epithelial protein lost in neoplasm (EPLIN), an actin-binding protein, has been described as both a tumor promoter and tumor suppressor in different cancers. The roles Read more

Extracellular vesicles bearing vimentin drive epithelial-mesenchymal transition

Sepideh Parvanian et al.

Mol Cell Proteomics. 2025 Jul 4:101028. doi: 10.1016/j.mcpro.2025.101028. Online ahead of print.

Published on July 6, 2025

Epithelial-mesenchymal transition (EMT) is a key biological process in physiological and pathological conditions, spanning development, wound healing, and cancer. Vimentin, a key cytoskeletal intermediate filament Read more

Structural Repetition Detector for multi-scale quantitative mapping of molecular complexes through microscopy

Afonso Mendes et al.

Nat Commun. 2025 Jul 1;16(1):5767. doi: 10.1038/s41467-025-60709-1.

Published on July 2, 2025

From molecules to organelles, cells exhibit recurring structural motifs across multiple scales. Understanding these structures provides insights into their functional roles. While super-resolution microscopy can Read more

Sketching T cell atlases in the single-cell era: challenges and recommendations

Itana Bojović et al.

Immunol Cell Biol. 2025 Jun 29. doi: 10.1111/imcb.70040. Online ahead of print.

Published on June 29, 2025

Recent advances in single-cell technologies have enabled the creation of comprehensive cell atlases, reference maps of various cell types within organisms. Here we specifically focus Read more

In situ construction of ossification micro-units for critical bone regeneration via sustained lifting of epigenetic suppression

Wu Yang et al.

J Control Release. 2025 Jun 23:113978. doi: 10.1016/j.jconrel.2025.113978. Online ahead of print.

Published on June 25, 2025

Critical-sized bone defects present significant clinical challenges due to insufficient stem cell recruitment, epigenetic suppression of osteogenesis, and inadequate mineralization. Among the epigenetic suppression mechanisms, Read more

Cytoskeletal crosstalk in macrophages: Vimentin drives ECM remodeling in tumor invasion and tissue plasticity

John E Eriksson et al.

Dev Cell. 2025 Jun 23;60(12):1655-1657. doi: 10.1016/j.devcel.2025.05.015.

Published on June 24, 2025

In this issue of Developmental Cell, Huang et al. assess the role of vimentin intermediate filaments during extracellular matrix (ECM) degradation by macrophages. Vimentin stabilizes Read more

Integrin β1 activity controls colony morphology during human pluripotent stem cell state transitions

Maria E Taskinen et al.

Stem Cell Reports. 2025 Jun 17:102538. doi: 10.1016/j.stemcr.2025.102538. Online ahead of print.

Published on June 20, 2025

Integrin β1-mediated adhesion is dispensable in early mouse embryogenesis (pre-implantation) but indispensable post-implantation, suggesting distinct roles for β1-integrin-mediated adhesions in the naive (pre-implantation) versus primed Read more

The Next Frontier: Unveiling Novel Approaches for Combating Multidrug-Resistant Bacteria

Praveen Mallari et al.

Pharm Res. 2025 Jun 16. doi: 10.1007/s11095-025-03871-x. Online ahead of print.

Published on June 16, 2025

CONCLUSION: Despite the substantial obstacles to getting bench findings to the patient, numerous scientists are still working towards this goal. Both the application of antibiotic Read more

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