Publications

    When publishing an article based on work performed at the Turku metabolomics Centre, please include for example the following acknowledgement: “Mass spectrometeric analysis was performed at the Turku Metabolomics Centre with the support of Biocenter Finland”

    Master’s theses

    Karmacharya, Pragya. Characterization of the dynamics of novel conjugated bile acids in relation to the development of islet cell autoantibodies. 2023.

    Salonen, Katja. Development of liquid chromatography–ion mobility mass spectrometry method for profiling novel N-acyl amides in fecal samples. 2024.

    Laamanen, Tomas. On the Impact of Statin Treatment and Hypoxia on the Metabolism of In Vitro Grown Prostate Cancer Cells. 2024. (Not affiliated with Turku Bioscience)

    Strandberg Teddie, LC-MS-analys av omvandlingsprodukter av ibuprofen. 2024 (Not affiliated with Turku Bioscience)

    Scientific articles

    Cruz AK, Alves MA, Andresson T, Bayless AL, Bloodsworth KJ, Bowden JA, Bullock K, Burnet MC, Neto FC, Choy A, Clish CB, Couvillion SP, Cumeras R, Dailey L, Dallmann G, Davis WC, Deik AA, Dickens AM, Djukovic D, Dorrestein PC, Eder JG, Fiehn O, Flores R, Gika H, Hagiwara KA, Pham TH, Harynuk JJ, Aristizabal-Henao JJ, Hoyt DW, Jean-François F, Kråkström M, Kumar A, Kyle JE, Lamichhane S, Li Y, Nam SL, Mandal R, de la Mata AP, Meehan MJ, Meikopoulos T, Metz TO, Mouskeftara T, Munoz N, Gowda GAN, Orešic M, Panitchpakdi M, Pierre-Hugues S, Raftery D, Rushing B, Schock T, Seifried H, Servetas S, Shen T, Sumner S, Carrillo KST, Thibaut D, Trejo JB, Van Meulebroek L, Vanhaecke L, Virgiliou C, Weldon KC, Wishart DS, Zhang L, Zheng J, Da Silva S. Multiplatform metabolomic interlaboratory study of a whole human stool candidate reference material from omnivore and vegan donors. Metabolomics. 2024 Nov 4;20(6):125. doi: 10.1007/s11306-024-02185-0. PMID: 39495321.

    Kortesluoma S, Aatsinki A-K, Perasto L, Korhonen L, Tuulari JJ, Lukkarinen M, Munukka E, Lahti L, Kråkström M, Lamichhane S, Karlsson H, Karlsson L, Dickens A. Associations between stress responses and gut microbiota metabolites among maternal prenatal psychological distress-exposed infants: FinnBrain Birth Cohort Study. Psychoneuroendocrinology. 2024;160(Suppl):106828. doi:10.1016/j.psyneuen.2023.106828

    Wang Y, Liu C, Ma X, Filppula A, Cui Y, Ye J, Zhang H. Encapsulated mitochondria to reprogram the metabolism of M2-type macrophages for anti-tumor therapy. Nanoscale 2024, 45, doi: https://doi.org/10.1039/d4nr02471k.

    Torta F, Hoffmann N, Burla B, Alecu I, Arita M, Bamba T, Bennett SAL, Bertrand-Michel J, Brügger B, Cala MP, Camacho-Muñoz D, Checa A, Chen M, Chocholoušková M, Cinel M, Chu-Van E, Colsch B, Coman C, Connell L, Sousa BC, Dickens AM, Fedorova M, Eiríksson FF, Gallart-Ayala H, Ghorasaini M, Giera M, Guan XL, Haid M, Hankemeier T, Harms A, Höring M, Holčapek M, Hornemann T, Hu C, Hülsmeier AJ, Huynh K, Jones CM, Ivanisevic J, Izumi Y, Köfeler HC, Lam SM, Lange M, Lee JC, Liebisch G, Lippa K, Lopez-Clavijo AF, Manzi M, Martinefski MR, Math RGH, Mayor S, Meikle PJ, Monge ME, Moon MH, Muralidharan S, Nicolaou A, Nguyen-Tran T, O’Donnell VB, Orešič M, Ramanathan A, Riols F, Saigusa D, Schock TB, Schwartz-Zimmermann H, Shui G, Singh M, Takahashi M, Thorsteinsdóttir M, Tomiyasu N, Tournadre A, Tsugawa H, Tyrrell VJ, van der Gugten G, Wakelam MO, Wheelock CE, Wolrab D, Xu G, Xu T, Bowden JA, Ekroos K, Ahrends R, Wenk MR. Concordant inter-laboratory derived concentrations of ceramides in human plasma reference materials via authentic standards. Nat Commun. 2024 Oct 3;15(1):8562. doi: 10.1038/s41467-024-52087-x. PMID: 39362843; PMCID: PMC11449902.

    Isokääntä H, Pinto da Silva L, Karu N, Kallonen T, Aatsinki AK, Hankemeier T, Schimmel L, Diaz E, Hyötyläinen T, Dorrestein PC, Knight R, Orešič M, Kaddurah-Daouk R, Dickens AM, Lamichhane S. Comparative Metabolomics and Microbiome Analysis of Ethanol versus OMNImet/gene•GUT Fecal Stabilization. Anal Chem. 2024 Jun 4;96(22):8893-8904. doi: 10.1021/acs.analchem.3c04436. Epub 2024 May 23. PMID: 38782403; PMCID: PMC11154662.

    Thapa K, Kadiri JJ, Saukkonen K, Pennanen I, Ghimire B, Cai M, Savontaus E, Rinne P. Melanocortin 1 receptor regulates cholesterol and bile acid metabolism in the liver. Elife. 2023 Jul 25;12:e84782. doi: 10.7554/eLife.84782. PMID: 37490042; PMCID: PMC10368426.

    Lamichhane S, Sen P, Dickens AM, Kråkström M, Ilonen J, Lempainen J, Hyöty H, Lahesmaa R, Veijola R, Toppari J, Hyötyläinen T, Knip M, Orešič M. Circulating metabolic signatures of rapid and slow progression to type 1 diabetes in islet autoantibody-positive children. Front Endocrinol (Lausanne). 2023 Sep 6;14:1211015. doi: 10.3389/fendo.2023.1211015. PMID: 37745723; PMCID: PMC10516565.

    Kråkström M, Dickens AM, Alves MA, Forssten SD, Ouwehand AC, Hyötyläinen T, Orešič M, Lamichhane S. Dynamics of the Lipidome in a Colon Simulator. Metabolites. 2023 Feb 27;13(3):355. doi: 10.3390/metabo13030355. PMID: 36984795; PMCID: PMC10051596.

    Chester LA, Englund A, Chesney E, Oliver D, Wilson J, Sovi S, Dickens AM, Oresic M, Linderman T, Hodsoll J, Minichino A, Strang J, Murray RM, Freeman TP, McGuire P. Effects of Cannabidiol and Delta-9-Tetrahydrocannabinol on Plasma Endocannabinoid Levels in Healthy Volunteers: A Randomized Double-Blind Four-Arm Crossover Study. Cannabis Cannabinoid Res. 2022 Dec 9. doi: 10.1089/can.2022.0174. Epub ahead of print. PMID: 36493386.

    Kantonen T, Pekkarinen L, Karjalainen T, Bucci M, Kalliokoski K, Haaparanta-Solin M, Aarnio R, Dickens AM, von Eyken A, Laitinen K, Houttu N, Kirjavainen AK, Helin S, Hirvonen J, Rönnemaa T, Nuutila P, Nummenmaa L. Obesity risk is associated with altered cerebral glucose metabolism and decreased μ-opioid and CB1 receptor availability. Int J Obes (Lond). 2022 Feb;46(2):400-407. doi: 10.1038/s41366-021-00996-y. Epub 2021 Nov 2. PMID: 34728775; PMCID: PMC8794779.

    Thomas I, Dickens AM, Posti JP, Czeiter E, Duberg D, Sinioja T, Kråkström M, Retel Helmrich IRA, Wang KKW, Maas AIR, Steyerberg EW, Menon DK, Tenovuo O, Hyötyläinen T, Büki A, Orešič M; CENTER-TBI Participants and Investigators. Serum metabolome associated with severity of acute traumatic brain injury. Nat Commun. 2022 May 10;13(1):2545. doi: 10.1038/s41467-022-30227-5. PMID: 35538079; PMCID: PMC9090763.

    Lamichhane S, Sen P, Dickens AM, Alves MA, Härkönen T, Honkanen J, Vatanen T, Xavier RJ, Hyötyläinen T, Knip M, Orešič M. Dysregulation of secondary bile acid metabolism precedes islet autoimmunity and type 1 diabetes. Cell Rep Med. 2022 Oct 18;3(10):100762. doi: 10.1016/j.xcrm.2022.100762. Epub 2022 Oct 3. PMID: 36195095; PMCID: PMC9589006.

    Lamichhane S, Dickens AM, Sen P, Laurikainen H, Borgan F, Suvisaari J, Hyötyläinen T, Howes O, Hietala J, Orešič M. Association Between Circulating Lipids and Future Weight Gain in Individuals With an At-Risk Mental State and in First-Episode Psychosis. Schizophr Bull. 2021 Jan 23;47(1):160-169. doi: 10.1093/schbul/sbaa087. PMID: 32609372; PMCID: PMC7825089.

    Dickens AM, Sen P, Kempton MJ, Barrantes-Vidal N, Iyegbe C, Nordentoft M, Pollak T, Riecher-Rössler A, Ruhrmann S, Sachs G, Bressan R, Krebs MO, Amminger GP, de Haan L, van der Gaag M, Valmaggia L, Hyötyläinen T; EU-GEI High Risk Study Group; Orešič M, McGuire P. Dysregulated Lipid Metabolism Precedes Onset of Psychosis. Biol Psychiatry. 2021 Feb 1;89(3):288-297. doi: 10.1016/j.biopsych.2020.07.012. Epub 2020 Jul 25. PMID: 32928501.

    Sen P, Andrabi SBA, Buchacher T, Khan MM, Kalim UU, Lindeman TM, Alves MA, Hinkkanen V, Kemppainen E, Dickens AM, Rasool O, Hyötyläinen T, Lahesmaa R, Orešič M. Quantitative genome-scale metabolic modeling of human CD4+ T cell differentiation reveals subset-specific regulation of glycosphingolipid pathways. Cell Rep. 2021 Nov 9;37(6):109973. doi: 10.1016/j.celrep.2021.109973. PMID: 34758307.