April 4^th at 12:00
On-site event
Presidentti auditorium, BioCity
Spring 2024 program

Prof. Ricardo Henriques, Instituto Gulbenkian de Ciência, Portugal
Open Super-Resolution and AI technologies in the quest for nanoscale live-cell imaging
Host: Guillaume Jaquemet (guillaume.jaquemet@abo.fi)

Coffee and sandwich at 11:45, first come first served!

Six PhD researchers and early-career postdocs are welcome to have a lunch in restaurant Mauno and discuss with Prof. Henriques after the seminar. This is a great possibility to learn hosting skills in friendly environment and create connections for future. Everyone is welcome to join, BioCity Turku will offer the lunch.

If you got interested, please send an email to biocityturku@bioscience.fi

The Henriques lab was established in 2013 to undertake research combining cell biology, optical physics and biochemistry. The group focuses on biological problems that cannot be addressed with current imaging technology, and thus aims to develop analytical, optical and biochemical approaches to address these questions. In cell biology the group aims to understand how viruses enter cells by probing and remodelling membranes, and what are the structural changes viruses undergo during cell-entry, uncoating and morphogenesis. To do so, they are developing new classes of fluorescent probes, high-speed cell friendly Super-Resolution (SR) methods and computational modelling approaches that, although designed to answer questions of interest in the lab, will have broad applications in cell biology research.

Selected publications

Laine RF, Heil HS, Coelho S, Nixon-Abell J, Jimenez A, Wiesner T, Martínez D, Galgani T, Régnier L, Stubb A, Follain G, Webster S, Goyette J, Dauphin A, Salles A, Culley S, Jacquemet G, Hajj B, Leterrier C, Henriques R. 2023. High-fidelity 3D live-cell nanoscopy through data-driven enhanced super-resolution radial fluctuation. Nat Methods. 2023 Dec;20(12):1949-1956. doi: 10.1038/s41592-023-02057-w

Spahn C, Gómez-de-Mariscal E, Laine RF, Pereira PM, von Chamier L, Conduit M, Pinho MG, Jacquemet G, Holden S, Heilemann M, Henriques R. 2022. DeepBacs for multi-task bacterial image analysis using open-source deep learning approaches. Commun Biol. 2022 Jul 9;5(1):688. doi: 10.1038/s42003-022-03634-z

von Chamier L, Laine RF, Jukkala J, Spahn C, Krentzel D, Nehme E, Lerche M, Hernández-Pérez S, Mattila PK, Karinou E, Holden S, Solak AC, Krull A, Buchholz TO, Jones ML, Royer LA, Leterrier C, Shechtman Y, Jug F, Heilemann M, Jacquemet G, Henriques R. 2021. Democratising deep learning for microscopy with ZeroCostDL4Mic. Nat Commun. 2021 Apr 15;12(1):2276. doi: 10.1038/s41467-021-22518-0

Spark A, Kitching A, Esteban-Ferrer D, Handa A, Carr AR, Needham LM, Ponjavic A, Santos AM, McColl J, Leterrier C, Davis SJ, Henriques R, Lee SF. 2020. vLUME: 3D virtual reality for single-molecule localization microscopy. Nat Methods. 2020 Nov;17(11):1097-1099. doi: 10.1038/s41592-020-0962-1

General information

• You can download and save all the spring 2024 FoS-seminars to your calendar from here: https://seafile.utu.fi/d/44a70f80ac1e46a9ad0a/
• Registration is not needed, participation list is circulated in the audience
• If you are a student and later wish to get a certificate of attendance from the Frontier of Science seminars, print out the seminar diary and after the seminar ask the BioCity coordinator to sign it https://seafile.utu.fi/d/44a70f80ac1e46a9ad0a/
• Please note that any audio or video recording of the seminars is strictly forbidden.
• Spring 2024 FoS image credits to Jenny Pessa: Transformed human breast epithelial HS578T cells (flattened), labelled with commercial fluorescent antibodies. Image acquired on 3i CSU-W1 Spinning disk with 40x objective.