Immunology Seminar Series

April 4th at 14:00 – 15:00 (Finland time)

Virtual event
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Wilfried Ellmeier, Institute of Immunology, Medical University of Vienna: “Histone deacetylases and the control of CD4+ T cell-mediated immunity”

Host: Riitta Lahesmaa (rilahes@utu.fi )

Registration latest April 3rd at https://link.webropolsurveys.com/S/1CACC360E8233FFF

Immunology seminar series is jointly organised by the Finnish Society for Immunology, InFLAMES Flagship and Turku Bioscience. For further information contact Anne Lahdenperä (ankahy@utu.fi) or Riitta Lahesmaa (rilahes@utu.fi), University of Turku.

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Wilfried Ellmeier is Professor of Immunobiology and Head of the Institute of Immunology at the Medical University of Vienna, Austria. He studied biochemistry at the University of Vienna, carried out his doctoral thesis at the Research Institute of Molecular Pathology (IMP Vienna) and performed postdoctoral studies at the Skirball Institute (NYU Medical Center) in New York. His research interests focus on epigenetic and transcriptional control mechanisms that regulate T cell development and T cell-mediated immunity. He received several prizes including the START program award for highly-qualified young scientists from the Austrian Science Fund and the Novartis award for biology. Wilfried Ellmeier is a corresponding member of the Austrian Academy of Sciences and a board member of the Austrian Science Fund. He is president-elect (2023-2024) of the Austrian Society of Allergology and Immunology (ÖGAI). He also has a strong interest in science policy and served as the President (2020-2021) of the BioMed Alliance in Europe.

References related to the topic of the talk:

Ellmeier, W. & Seiser, C. Histone deacetylase function in CD4(+) T cells. Nat Rev Immunol 18, 617-634, doi:10.1038/s41577-018-0037-z (2018)

Preglej T, Hamminger P, Luu M, Bulat T, Andersen L, Göschl L, Stolz V, Rica R, Sandner L, Waltenberger D, Tschismarov R, Faux T, Boenke T, Laiho A, Elo LL, Sakaguchi S, Steiner G, Decker T, Bohle B, Visekruna A, Bock C, Strobl B, Seiser C, Boucheron N, Ellmeier W. (2020). Histone deacetylases 1 and 2 restrain CD4+ cytotoxic T lymphocyte differentiation. JCI Insight. 5(4):e133393. doi: 10.1172/jci.insight.133393

Hamminger P, Marchetti L, Preglej T, Platzer R, Zhu C, Kamnev A, Rica R, Stolz V, Sandner L, Alteneder M, Kaba E, Waltenberger D, Huppa JB, Trauner M, Bock C, Lyck R, Bauer J, Dupré L, Seiser C, Boucheron N, Engelhardt B, Ellmeier W. (2021). Histone deacetylase 1 controls CD4+ T cell trafficking in autoinflammatory diseases. J Autoimmun. 119:102610. doi: 10.1016/j.jaut.2021.102610