Selected Publications using the services of the Turku Proteomics Facility
Publications 2023
Structural mechanism for inhibition of PP2A-B56α and oncogenicity by CIP2A
Karolina Pavic, Nikhil Gupta, Judit Domènech Omella, Rita Derua, Anna Aakula, Riikka Huhtaniemi, Juha A. Määttä, Nico Höfflin, Juha Okkeri, Zhizhi Wang, Otto Kauko, Roosa Varjus, Henrik Honkanen, Daniel Abankwa, Maja Köhn, Vesa P. Hytönen, Wenqing Xu, Jakob Nilsson, Rebecca Page, Veerle Janssens, Alexander Leitner, Jukka Westermarck
Nature Communications
AbstractThe protein phosphatase 2A (PP2A) heterotrimer PP2A-B56α is a human tumour suppressor. However, the molecular mechanisms inhibiting PP2A-B56α in cancer...
https://doi.org/10.1038/s41467-023-36693-9Targeted serum proteomics of longitudinal samples from newly diagnosed youth with type 1 diabetes distinguishes markers of disease and C-peptide trajectory
Robert Moulder, Tommi Välikangas, M. Karoliina Hirvonen, Tomi Suomi, Caroline A. Brorsson, Niina Lietzén, Sylvaine F. A. Bruggraber, Lut Overbergh, David B. Dunger, Mark Peakman, Piotr J. Chmura, Soren Brunak, Anke M. Schulte, Chantal Mathieu, Mikael Knip, Laura L. Elo, Riitta Lahesmaa,
Diabetologia
Abstract Aims/hypothesis There is a growing need for markers that could help indicate the decline in beta cell function and...
https://doi.org/10.1007/s00125-023-05974-9