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    Publications

    Selected Recent Publications

    • Sabt, A., Kitsos, S., Ebaid, M.S., Furlan, V.,  Pantiora, P. D., Tsolka, M., Elkaeed, E.B., Hamissa, M.F., Angelis, N., Tsitsilonis, O.E., Papageorgiou, A.C., Bren, U. & Labrou, N.E. (2024) Novel Coumarin-6-Sulfonamide-Chalcone Hybrids as Glutathione Transferase P1-1 Inhibitors. PLoS ONE 19(8): e0306124 DOI
    • Tsouri, S., Tselo, E., Premetis, G. E., Furlan, V., Pantiora, P. D., Mavroidi, B., et al. (2024) A Monocarbonyl Curcuminoid Derivative Inhibits the Activity of Human Glutathione Transferase A4-4 and Chemosensitizes Glioblastoma Cells to Temozolomide. Pharmaceuticals 17 (3), 365
    • Varotsou, C., Ataya, F., Papageorgiou, A.C. & Labrou, N.E. (2024) Structural studies of Klebsiella pneumoniae fosfomycin-resistance protein and its application for the development of an optical biosensor for fosfomycin determination. Int J Mol Sci 25 (1), 85 Pubmed DOI
    • Premetis, E.G., Stathi, A., Papageorgiou, A.C. & Labrou, N.E. (2023) Structural and Functional Features of a Broad-Spectrum Prophage-Encoded Enzybiotic from Enterococcus Faecium. Sci Rep 13, 7450 Pubmed
    • Kupreienko, O., Pouliou, F., Constandinidis, C., Axarli, I., Douni, E., Papageorgiou, A.C. Nikolaos E. Labrou, N.E. (2023) Inhibition Analysis and High-resolution Crystal Structure of Mus musculus Glutathione Transferase P1-1. Biomolecules, 13(4), 613 DOI
    • Chronopoulou, E.G., Mutabdzija, L., Poudel, N., Papageorgiou, A.C. & Labrou, N.E. (2023) A key role in catalysis and enzyme thermostability of a conserved helix H5 motif of human glutathione transferase A1-1. Int J Mol Sci 24(4):3700 Pubmed
    • Pantiora, P., Furlan, V., Matiadis, D., Mavroidi, B., Perperopoulou, F., Papageorgiou, A.C., Sagnou, M., Bren, U., Pelecanou, M. & Labrou, N.E. (2023) Monocarbonyl curcumin analogues as potent inhibitors against human glutathione transferase P1-1. Antioxidants 12(1):63 Pubmed
    • Premetis, E.G., Stathi, A., Papageorgiou, A.C & Labrou, N.E. (2022) Characterization of a glycoside hydrolase endolysin from Acinetobacter baumannii phage AbTZA1 with high antibacterial potency and novel structural features. FEBS J. doi: 10.1111/febs.16686 Pubmed
    • Lyu, Y., Wu, X., Papageorgiou, A.C., Yang; J., Wang; X., Qi, D., Li J. (2022) Dynamic Covalent Macrocycles Co-delivering Genes and Drugs against Drug-Resistant Cancer. Cell Rep Phys Sci 3, 101150 DOI
    • Yu, J., Qi, D., Mäkilä, E., Lassila, L., Papageorgiou, A.C., Peurla, M., Rosenholm, J., Zhao, Z., Vallittu, P., Jalkanen, S., Jia, C., and Li, J. (2022) Supramolecular Plastics Processed from Small Molecule-based Coacervates. Angew. Chem. Int. Ed. 61 (39) DOI: 10.1002/anie.202204611 Pubmed
    • Ioannou, E., Papageorgiou, A.C. and Labrou, N.E. (2022) Directed Evolution of Phi Class Glutathione Transferases Involved in Multiple-Herbicide Resistance of Grass Weeds and Crops. Int. J. Mol. Sci., 23(13), 7469 Pubmed
    • Bodourian, C.S., Poudel, N., Papageorgiou, A.C., Antoniadi, M., Georgakis, N.D., Abe, H. & Labrou, N.E. (2022) Ligandability Assessment of Human Glutathione Transferase M1-1 using Pesticides as Chemical Probes. Int. J. Mol. Biol. 25;23(7):3606 Pubmed
    • Yu, J., Qi, D., Mäkilä, E., Lassila, L., Papageorgiou, A.C., Peurla, M., Rosenholm, J., Zhao, Z., Vallittu, P., Jalkanen, S., Jia, C., and Li, J. (2022) Supramolecular Plastics Processed from Small Molecule-based Coacervates. ChemRxiv. doi:10.26434/chemrxiv-2022-snwcn (this content is a preprint and has not been peer-reviewed)
    • Yu, W., Mohsin, I., Papageorgiou, A.C. & Li, D.-C. (2022) Purification and structural characterization of the native AA9 lytic polysaccharide monooxygenase from Thermoascus aurantiacus and identification of its C1- and C4-oxidized reaction productions. Catalysts 12, 139 DOI
    • Perperopoulou, F., Poudel, N., Ataya, F., Papageorgiou, A.C. & Labrou, N.E. (2022) Structural and functional characterization of Camelus dromedarius Glutathione transferase M1-1. Life 12(1), 106 Pubmed
    • Mohsin, I. & Papageorgiou, A.C. (2022) Fungal extremozymes: A potential bioresource for green chemistry. In: Sahay, S. (eds) Extremophilic Fungi. Springer, Singapore DOI
    • Papageorgiou, A. C. (2022) Structural characterization of multienzyme assemblies: An overview. Methods Mol Biol 2487:51-72 Pubmed
    • Perperopoulou, F., Fragoulaki, M., Papageorgiou, A.C. & Labrou, N.E. (2021) Directed evolution of a glutathione transferase for the development of a biosensor for alachlor determination. Symmetry 13 (3), 461 DOI
    • Mohsin, I., Zhang, L.-Q., Li, D.-C.& Papageorgiou, A.C. (2021) Crystal structure of a Cu,Zn superoxide dismutase from the thermophilic fungus Chaetomium thermophilum. Protein Pept. Lett 28, 1043-1053 Pubmed
    • Platis, M., Vlachakis, D., Foudah, A.I., Muharram, M.M, Alqarni, M.H., Papageorgiou, A.C. & Labrou, N.E. (2021) The interaction of Schistosoma japonicum glutathione transferase with Cibacron blue 3GA and its fragments. Med Chem 7, 332-343 Pubmed
    • Georgakis, N., Poudel, N., Vlachakis, D., Papageorgiou, A.C. & Labrou, N.E. (2021) Phi class glutathione transferases as molecular targets towards multiple-herbicide resistance: Inhibition analysis and pharmacophore design. Plant Physiol Biochem 158, 342-352 Pubmed
    • Papageorgiou, A.C., Poudel, N. & Matsson, J. (2021) Protein structure analysis and validation with X-ray crystallography. Methods Mol. Biol 2178, 377-404  Pubmed
    • Papageorgiou, A.C. & Mohsin, I. (2020) The SARS-CoV-2 spike glycoprotein as a drug and vaccine target: Structural insights into its complexes with ACE2 and antibodies. Cells 9, 2343 Pubmed
    • Johansson M.M., Bélurier E., Papageorgiou A.C., Sundin A.P., Rahkila J., Kallonen T., Nilsson U.J., Maatsola S., Nyholm T.K.M., Käpylä J., Corander J., Leino R., Finne J., Teneberg S. & Haataja S. (2020) The binding mechanism of the virulence factor Streptococcus suis adhesin P subtype to globotetraosylceramide is associated with systemic disease. J. Biol. Chem. 295, 14304-14324 Pubmed
    • Premetis,G., Marugas, P., Fanos, G., Vlachakis, D., Chronopoulou, E.G., Perperopoulou, F., Dubey, K.K., Shukla, P., Foudah, A.I., Muharram, M.M., Aldwsari, M.F., Papageorgiou, A.C. & Labrou, N.E. (2020) The interaction of the microtubule targeting anticancer drug colchicine with human glutathione transferases. Curr Pharm Des 26, 5205-5212 Pubmed
    • Wang, L., Borghei, M., Ishfaq, A., Lahtinen, P., Ago, M., Papageorgiou, A.C., Lundahl, M., Johansson, L.S., Kallio, T. & Rojas, O.J. (2020) Mesoporous carbon microfibers for electroactive materials derived from lignin-containing nanocellulose ACS Sustain Chem Eng 8, 8549-8561
    • Georgakis; N., Poudel, N., Papageorgiou, A.C. & Labrou, N.E. (2020) Comparative structural and functional analysis of phi class glutathione transferases involved in multiple-herbicide resistance of grass weeds and crops. Plant Physiol Biochem 149, 266-276 Pubmed
    • Siddiqui, F.A., Alam, C., Rosenqvist, P., Ora, M., Sabt, A., Manoharan, G., Bindu, L., Okutachi, S., Catillon, M., Taylor, T., Abdelhafez, O.M., Lönnberg, H., Stephen, A.G., Papageorgiou, A.C., Virta, P. & Abankwa, D. (2020) PDE6D inhibitors with a new design principle selectively block K-Ras activity ACS Omega 5, 832-842 Pubmed
    • Mohsin, I., Poudel, N., Li, D.-C. & Papageorgiou, A.C. (2019) Crystal structure of a GH3 b-glucosidase from the thermophilic fungus Chaetomium thermophilum. Intern J Mol Sci 20, 5962 Pubmed
    • Wang, L., Lundahl, M.J., Greca, L.G., Papageorgiou, A.C., Borghei, M. & Rojas, O.M. (2019) Effects of non-solvents and electrolytes on the formation and properties of cellulose I filaments  Sci Reports 9, 16691 Pubmed
    • Papageorgiou, A.C. (2019) X-ray crystallography in structure-function characterization of therapeutic enzymes Adv Exp Med Biol 1148, 81-10 Pubmed
    • Li, D.-C & Papageorgiou, A.C. (2019). Cellulases from thermophilic fungi: Recent insights and biotechnological applications In Extreme Environments: Ecological Role and Biotechnological Significance ed. S. Tiquia-Arashiro & Grube, M., Springer International Publishing
    • Wang. L., Ago, M., Borghei, M., Ishaq, A., Papageorgiou, A.C., Lundahl, M. & Rojas, O.M. (2019) Conductive carbon microfibers derived from wet-spun lignin/nanocellulose hydrogels. ACS Sustain Chem Eng 7 (6), 6013-6022 Link
    • Theoharaki, C., Chronopoulou, E., Vlachakis, D., Ataya, F.S., Giannopoulos, P., Mavrikou, S., Skopelitou, K., Papageorgiou, A.C. & Labrou, N.E. (2019) Delineation of the functional and structural properties of the glutathione transferase family from the plant pathogen Erwinia carotovora. Funct. Integr. Genomics 19:1-12  Pubmed