Publications

    All Publications (240)

    SNM1A is crucial for efficient repair of complex DNA breaks in human cells 
    Lonnie P Swift et al. Nat Commun. 2024 Jun 25;15(1):5392. doi: 10.1038/s41467-024-49583-5. Published June 25, 2024
    DNA double-strand breaks (DSBs), such as those produced by radiation and radiomimetics, are amongst the most toxic forms of cellular damage, in part because they...
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    Wnt/β-catenin-YAP axis in the pathogenesis of primary intraosseous carcinoma NOS, deriving from odontogenic keratocyst 
    Yusuke Nakako et al. Pathol Res Pract. 2024 Aug;260:155420. doi: 10.1016/j.prp.2024.155420. Epub 2024 Jun 20. Published June 22, 2024
    Odontogenic tumors (OGTs), which originate from cells of odontogenic apparatus and their remnants, are rare entities. Primary intraosseous carcinoma NOS (PIOC), is one of the...
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    DUSP6 inhibition overcomes neuregulin/HER3-driven therapy tolerance in HER2+ breast cancer 
    Majid Momeny et al. EMBO Mol Med. 2024 Jul;16(7):1603-1629. doi: 10.1038/s44321-024-00088-0. Epub 2024 Jun 17. Published June 17, 2024
    Despite clinical benefits of tyrosine kinase inhibitors (TKIs) in cancer, most tumors can reactivate proliferation under TKI therapy. Here we present transcriptional profiling of HER2+...
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    Serum proteomics of mother-infant dyads carrying HLA-conferred type 1 diabetes risk 
    Santosh D Bhosale et al. iScience. 2024 May 22;27(6):110048. doi: 10.1016/j.isci.2024.110048. eCollection 2024 Jun 21. Published June 17, 2024
    In-utero and dietary factors make important contributions toward health and development in early childhood. In this respect, serum proteomics of maturing infants can provide insights...
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    Improved breast milk proteome coverage by DIA based LC-MS/MS method 
    Jenni Viitaharju et al. Proteomics. 2024 Jul;24(14):e2300340. doi: 10.1002/pmic.202300340. Epub 2024 Jun 14. Published June 14, 2024
    The breast milk composition includes a multitude of bioactive factors such as viable cells, lipids and proteins. Measuring the levels of specific proteins in breast...
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    Indignity of Nazi data: reflections on the utilization of illicit research 
    Iman Farahani et al. Med Health Care Philos. 2024 Sep;27(3):381-387. doi: 10.1007/s11019-024-10212-z. Epub 2024 Jun 6. Published June 6, 2024
    Human rights may feel self-apparent to us, but less than 80 years ago, one of the most advanced countries at the time acted based on...
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    Identification and validation of a blood- based diagnostic lipidomic signature of pediatric inflammatory bowel disease 
    Samira Salihovic et al. Nat Commun. 2024 Jun 3;15(1):4567. doi: 10.1038/s41467-024-48763-7. Published June 3, 2024
    Improved biomarkers are needed for pediatric inflammatory bowel disease. Here we identify a diagnostic lipidomic signature for pediatric inflammatory bowel disease by analyzing blood samples...
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    Trans-activating mutations of the pseudokinase ERBB3 
    Marika K A Koivu et al. Oncogene. 2024 Jul;43(29):2253-2265. doi: 10.1038/s41388-024-03070-9. Epub 2024 May 28. Published May 28, 2024
    Genetic changes in the ERBB family of receptor tyrosine kinases serve as oncogenic driver events and predictive biomarkers for ERBB inhibitor drugs. ERBB3 is a...
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    Long noncoding RNA LIRIL2R modulates FOXP3 levels and suppressive function of human CD4+ regulatory T cells by regulating IL2RA 
    Syed Bilal Ahmad Andrabi et al. Proc Natl Acad Sci U S A. 2024 Jun 4;121(23):e2315363121. doi: 10.1073/pnas.2315363121. Epub 2024 May 28. Published May 28, 2024
    Regulatory T cells (Tregs) are central in controlling immune responses, and dysregulation of their function can lead to autoimmune disorders or cancer. Despite extensive studies...
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    A proximal enhancer regulates RORA expression during early human Th17 cell differentiation 
    Ubaid Ullah Kalim et al. Clin Immunol. 2024 Jul;264:110261. doi: 10.1016/j.clim.2024.110261. Epub 2024 May 22. Published May 24, 2024
    Gene regulatory elements, such as enhancers, greatly influence cell identity by tuning the transcriptional activity of specific cell types. Dynamics of enhancer landscape during early...
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    Comparative Metabolomics and Microbiome Analysis of Ethanol versus OMNImet/gene•GUT Fecal Stabilization 
    Heidi Isokääntä et al. Anal Chem. 2024 Jun 4;96(22):8893-8904. doi: 10.1021/acs.analchem.3c04436. Epub 2024 May 23. Published May 23, 2024
    Metabolites from feces provide important insights into the functionality of the gut microbiome. As immediate freezing is not always feasible in gut microbiome studies, there...
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    Serum hydroxysteroid (17beta) dehydrogenase 1 concentration in pregnant women correlates with pregnancy-associated plasma protein A but does not serve as an independent marker for preeclampsia† 
    Taija Heinosalo et al. Biol Reprod. 2024 Aug 15;111(2):436-447. doi: 10.1093/biolre/ioae078. Published May 23, 2024
    Hydroxysteroid (17beta) dehydrogenase 1 (HSD17B1) is a steroid synthetic enzyme expressed in ovarian granulosa cells and placental syncytiotrophoblasts. Here, HSD17B1 serum concentration was measured with...
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