Publications

    All Publications (242)

    Phosphoproteomic analysis reveals the diversity of signaling behind ErbB-inhibitor-induced phenotypes 
    Katri Vaparanta et al. FEBS J. 2025 Jul 24. doi: 10.1111/febs.70197. Online ahead of print. Published July 24, 2025
    The impact of kinase inhibitors on the phosphoproteome has been rarely investigated at a whole-organism level. Here, we performed a phosphoproteomic analysis in embryonic zebrafish...
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    Does cannabidiol reduce the adverse effects of cannabis in schizophrenia? A randomised, double-blind, cross-over trial 
    Edward Chesney et al. Neuropsychopharmacology. 2025 Jul 24. doi: 10.1038/s41386-025-02175-3. Online ahead of print. Published July 23, 2025
    In patients with schizophrenia, cannabis use exacerbates symptoms and can lead to a relapse of psychosis. Some experimental studies in healthy volunteers suggest that pre-treatment...
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    Correction: The PP2A regulator IER5L supports prostate cancer progression 
    Jana R Crespo et al. Cell Death Dis. 2025 Jul 22;16(1):545. doi: 10.1038/s41419-025-07802-x. Published July 22, 2025
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    LIMA1-alpha staining predicts curative intent surgery response in HPV negative head and neck cancer 
    Xi Qiao et al. EMBO Mol Med. 2025 Jul 17. doi: 10.1038/s44321-025-00266-8. Online ahead of print. Published July 17, 2025
    In many solid cancer types, surgery alone could be a sufficient first therapy option for a significant number of cancer patients. However, there are currently...
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    EPLINα controls integrin recycling from Rab21 endosomes to drive breast cancer cell migration 
    Niklas Z Jäntti et al. Dev Cell. 2025 Jul 9:S1534-5807(25)00403-4. doi: 10.1016/j.devcel.2025.06.025. Online ahead of print. Published July 16, 2025
    Epithelial protein lost in neoplasm (EPLIN), an actin-binding protein, has been described as both a tumor promoter and tumor suppressor in different cancers. The roles...
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    Extracellular vesicles bearing vimentin drive epithelial-mesenchymal transition 
    Sepideh Parvanian et al. Mol Cell Proteomics. 2025 Jul 4:101028. doi: 10.1016/j.mcpro.2025.101028. Online ahead of print. Published July 6, 2025
    Epithelial-mesenchymal transition (EMT) is a key biological process in physiological and pathological conditions, spanning development, wound healing, and cancer. Vimentin, a key cytoskeletal intermediate filament...
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    Structural Repetition Detector for multi-scale quantitative mapping of molecular complexes through microscopy 
    Afonso Mendes et al. Nat Commun. 2025 Jul 1;16(1):5767. doi: 10.1038/s41467-025-60709-1. Published July 2, 2025
    From molecules to organelles, cells exhibit recurring structural motifs across multiple scales. Understanding these structures provides insights into their functional roles. While super-resolution microscopy can...
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    Sketching T cell atlases in the single-cell era: challenges and recommendations 
    Itana Bojović et al. Immunol Cell Biol. 2025 Jun 29. doi: 10.1111/imcb.70040. Online ahead of print. Published June 29, 2025
    Recent advances in single-cell technologies have enabled the creation of comprehensive cell atlases, reference maps of various cell types within organisms. Here we specifically focus...
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    In situ construction of ossification micro-units for critical bone regeneration via sustained lifting of epigenetic suppression 
    Wu Yang et al. J Control Release. 2025 Jun 23:113978. doi: 10.1016/j.jconrel.2025.113978. Online ahead of print. Published June 25, 2025
    Critical-sized bone defects present significant clinical challenges due to insufficient stem cell recruitment, epigenetic suppression of osteogenesis, and inadequate mineralization. Among the epigenetic suppression mechanisms,...
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    Cytoskeletal crosstalk in macrophages: Vimentin drives ECM remodeling in tumor invasion and tissue plasticity 
    John E Eriksson et al. Dev Cell. 2025 Jun 23;60(12):1655-1657. doi: 10.1016/j.devcel.2025.05.015. Published June 24, 2025
    In this issue of Developmental Cell, Huang et al. assess the role of vimentin intermediate filaments during extracellular matrix (ECM) degradation by macrophages. Vimentin stabilizes...
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    Integrin β1 activity controls colony morphology during human pluripotent stem cell state transitions 
    Maria E Taskinen et al. Stem Cell Reports. 2025 Jun 17:102538. doi: 10.1016/j.stemcr.2025.102538. Online ahead of print. Published June 20, 2025
    Integrin β1-mediated adhesion is dispensable in early mouse embryogenesis (pre-implantation) but indispensable post-implantation, suggesting distinct roles for β1-integrin-mediated adhesions in the naive (pre-implantation) versus primed...
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    The Next Frontier: Unveiling Novel Approaches for Combating Multidrug-Resistant Bacteria 
    Praveen Mallari et al. Pharm Res. 2025 Jun 16. doi: 10.1007/s11095-025-03871-x. Online ahead of print. Published June 16, 2025
    CONCLUSION: Despite the substantial obstacles to getting bench findings to the patient, numerous scientists are still working towards this goal. Both the application of antibiotic...
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