Dysregulated Lipid Metabolism Precedes Onset of Psychosis

    Alex M. Dickens, Partho Sen, Matthew J. Kempton, Neus Barrantes-Vidal, Conrad Iyegbe, Merete Nordentoft, Thomas Pollak, Anita Riecher-Rössler, Stephan Ruhrmann, Gabriele Sachs, Rodrigo Bressan, Marie-Odile Krebs, G. Paul Amminger, Lieuwe de Haan, Mark van der Gaag, Lucia Valmaggia, Tuulia Hyötyläinen, Philip McGuire, Lucia R. Valmaggia, Matthew J. Kempton, Maria Calem, Stefania Tognin, Gemma Modinos, Lieuwe de Haan, Mark van der Gaag, Eva Velthorst, Tamar C. Kraan, Daniella S. van Dam, Nadine Burger, Barnaby Nelson, Patrick McGorry, G. Paul Amminger, Christos Pantelis, Athena Politis, Joanne Goodall, Anita Riecher-Rössler, Stefan Borgwardt, Charlotte Rapp, Sarah Ittig, Erich Studerus, Renata Smieskova, Rodrigo Bressan, Ary Gadelha, Elisa Brietzke, Graccielle Asevedo, Elson Asevedo, Andre Zugman, Neus Barrantes-Vidal, Tecelli Domínguez-Martínez, Anna Racciopi, Thomas R. Kwapil, Manel Monsonet, Araceli Rosa, Ariel Frajerman, Boris Chaumette, Julie Bourgin, Oussama Kebir, Célia Jantac, Marie-Odile Krebs, Dorte Nordholm, Lasse Randers, Kristine Krakauer, Louise Glenthøj, Birte Glenthøj, Merete Nordentoft, Stephan Ruhrmann, Dominika Gebhard, Julia Arnhold, Joachim Klosterkötter, Gabriele Sachs, Iris Lasser, Bernadette Winklbaur, Philippe A. Delespaul, Bart P. Rutten, Jim van Os, Matej Orešič, Philip McGuire

    Biological Psychiatry (2021)

    Published on December 3, 2025

    DOI: https://doi.org/10.1016/j.biopsych.2020.07.012

    Core: Metabolomics
    ← Back to Publications
    User Publication
    <i>Staphylococcus aureus</i> Augments Epithelial Skin Barrier Damage Through T Cell Activation in Cutaneous T Cell Lymphoma
    M. Gluud et al. • 2026 • Allergy
    Core:Cytometry Core
    User Publication
    Fast label-free live imaging with FlowVision reveals key principles of cancer cell arrest on endothelial monolayers
    G. Follain et al. • 2026 • The EMBO Journal
    Core:Advanced Imaging Core
    User Publication
    Synthesis and Characterization of Glyco‐Decorated Silsesquioxane‐Metallosalen Complexes
    H. Haapsaari et al. • 2026 • ChemistrySelect
    Core:Protein Structure and Chemistry
    User Publication
    Functional characterization and directed evolution of Cicer arietinum glutathione transferases for enhanced hydroperoxidase activity and ligandin function
    A. Kontouri et al. • 2026 • Phytochemistry
    Core:Protein Structure and Chemistry
    User Publication
    Isomeric cues direct macrocycle selection from complex chemical systems for selective separation and recycling
    X. Wang et al. • 2026 • Cell Reports Physical Science
    Core:Protein Structure and Chemistry

    More Publications

    User Publication
    December 3, 2025
    Association Between Circulating Lipids and Future Weight Gain in Individuals With an At-Risk Mental State and in First-Episode Psychosis
    Santosh Lamichhane, Alex M Dickens, Partho Sen, Heikki Laurikainen, Faith Borgan, Jaana Suvisaari, Tuulia Hyötyläinen, Oliver Howes, Jarmo Hietala, Matej Orešič Schizophrenia Bulletin (2020)
    Abstract Patients with schizophrenia have a lower than average life span, largely due to the increased prevalence of cardiometabolic comorbidities....
    Read abstract
    User Publication
    December 3, 2025
    Circulating metabolic signatures of rapid and slow progression to type 1 diabetes in islet autoantibody-positive children
    Santosh Lamichhane, Partho Sen, Alex M. Dickens, Matilda Kråkström, Jorma Ilonen, Johanna Lempainen, Heikki Hyöty, Riitta Lahesmaa, Riitta Veijola, Jorma Toppari, Tuulia Hyötyläinen, Mikael Knip, Matej Orešič Frontiers in Endocrinology (2023)
    Aims/hypothesisAppearance of multiple islet cell autoantibodies in early life is indicative of future progression to overt type 1 diabetes, however,...
    Read abstract