Encapsulated mitochondria to reprogram the metabolism of M2-type macrophages for anti-tumor therapy

    Yonghui Wang, Chang Liu, Xiaodong Ma, Anne Filppula, Youbin Cui, Jiangbin Ye, Hongbo Zhang

    Nanoscale (2024)

    Published on December 3, 2025

    DOI: https://doi.org/10.1039/d4nr02471k

    Core: Advanced Imaging Core

    Abstract

    In this study, our innovative Mito@ZiF-8 system enhances the functionality of isolated mitochondria and reprograms M2 macrophage metabolism upon delivery, ultimately, reducing the tumorigenic potential of breast cancer cells.
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