The endothelial protein PLVAP in lymphatics controls the entry of lymphocytes and antigens into lymph nodes

    Pia Rantakari, Kaisa Auvinen, Norma Jäppinen, Maria Kapraali, Joona Valtonen, Marika Karikoski, Heidi Gerke, Imtiaz Iftakhar-E-Khuda, Johannes Keuschnigg, Eiji Umemoto, Kazuo Tohya, Masayuki Miyasaka, Kati Elima, Sirpa Jalkanen, Marko Salmi

    Nature Immunology (2015)

    Published on December 4, 2025

    DOI: https://doi.org/10.1038/ni.3101

    Core: Advanced Imaging Core
    ← Back to Publications
    Genes associated with immune response are upregulated in clinically healthy skin of patients with gliptin-associated bullous pemphigoid
    N. Kokkonen et al. • 2026 • Journal of Investigative Dermatology
    Core:Finnish Functional Genomics Centre
    Read more
    Improving genotyped functional screening: A versatile closed-tube PCR for Illumina library generation reduces background sequences in multiplexed sequencing
    S. Oksanen et al. • 2026 • SLAS Technology
    Core:Finnish Functional Genomics Centre
    Read more
    Dynamic landscape of transcription initiation by yeast RNA polymerase I
    O. Parilova et al. • 2026 • Nucleic Acids Research
    Abstract RNA polymerase I (Pol I) synthesizes precursor ribosomal RNA, a key step in ribosome biogenesis. Elevated Pol I activity...
    Core:Protein Structure and Chemistry
    Read more
    Staphylococcus aureus Augments Epithelial Skin Barrier Damage Through T Cell Activation in Cutaneous T Cell Lymphoma
    M. Gluud et al. • 2026 • Allergy
    ABSTRACT Background Skin barrier dysfunction is central to inflammation and susceptibility to infection in atopic dermatitis (AD). Cutaneous T‐cell lymphoma...
    Core:Cytometry Core
    Read more
    Fast label-free live imaging with FlowVision reveals key principles of cancer cell arrest on endothelial monolayers
    G. Follain et al. • 2026 • The EMBO Journal
    Abstract The rapid, transient, and unpredictable nature of interactions between circulating cells and the endothelium challenges the investigation of these...
    Core:Advanced Imaging Core
    Read more
    All user publications

    More User Publications

    User Publication
    December 3, 2025
    Volumetric analysis of the terminal ductal lobular unit architecture and cell phenotypes in the human breast
    Oona Paavolainen, Markus Peurla, Leena M. Koskinen, Jonna Pohjankukka, Kamyab Saberi, Ella Tammelin, Suvi-Riitta Sulander, Masi Valkonen, Larissa Mourao, Pia Boström, Nina Brück, Pekka Ruusuvuori, Colinda LGJ Scheele, Pauliina Hartiala, Emilia Peuhu (2023)
    AbstractThe major lactiferous ducts of the human breast branch out and ultimately end at terminal ductal lobular units (TDLUs). These...
    Read abstract