Publications & Acknowledgements

Single Cell Omics

Selected Publications

Publications 2025

Breast cancer remodels lymphatics in sentinel lymph nodes

Dominik Eichin, Diana Lehotina, Anni Kauko, Maki Uenaka, Meri Leppänen, Kati Elima, Minna Piipponen, Tapio Lönnberg, Pia Boström, Ilkka Koskivuo, Tero Aittokallio, Maija Hollmén, Akira Takeda, Sirpa Jalkanen
Nature Communications

Abstract Cancer metastasis to sentinel lymph nodes (LNs) is often the first marker of potential disease progression. Although it is...
https://doi.org/10.1038/s41467-025-64981-z

COVID-19 vaccine type controls stromal reprogramming in draining lymph nodes

Ruth Fair-Mäkelä, Pinja Thorén, Joni Näsiaho, Pia Sundqvist, Irina Piiroinen, Laura Kähäri, Ilkka Julkunen, Johanna Ivaska, Elin Hub, Antal Rot, Bishwa Ghimire, Jonna Alanko, Marko Salmi
Science Immunology

Lymph node (LN) stromal cells are critical regulators of immune reactions, yet their responses to different SARS-CoV-2 vaccines remain unexplored....
https://doi.org/10.1126/sciimmunol.adr6787

Single-cell transcriptome analysis of the early immune response in the lymph nodes of Borrelia burgdorferi-infected mice

Varpu Rinne, Kirsi Gröndahl-Yli-Hannuksela, Ruth Fair-Mäkelä, Marko Salmi, Pia Rantakari, Tapio Lönnberg, Jukka Alinikula, Annukka Pietikäinen, Jukka Hytönen
Microbes and Infection
https://doi.org/10.1016/j.micinf.2024.105424