Single Cell Omics Publications

    Publications 2025 (3)

    Breast cancer remodels lymphatics in sentinel lymph nodes
    Dominik Eichin, Diana Lehotina, Anni Kauko, Maki Uenaka, Meri Leppänen, Kati Elima, Minna Piipponen, Tapio Lönnberg, Pia Boström, Ilkka Koskivuo, Tero Aittokallio, Maija Hollmén, Akira Takeda, Sirpa JalkanenNature Communications (2025)
    Abstract Cancer metastasis to sentinel lymph nodes (LNs) is often the first marker of potential disease progression. Although it is...
    Core:Single Cell Omics
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    COVID-19 vaccine type controls stromal reprogramming in draining lymph nodes
    Ruth Fair-Mäkelä, Pinja Thorén, Joni Näsiaho, Pia Sundqvist, Irina Piiroinen, Laura Kähäri, Ilkka Julkunen, Johanna Ivaska, Elin Hub, Antal Rot, Bishwa Ghimire, Jonna Alanko, Marko SalmiScience Immunology (2025)
    Lymph node (LN) stromal cells are critical regulators of immune reactions, yet their responses to different SARS-CoV-2 vaccines remain unexplored....
    Core:Single Cell Omics
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    Single-cell transcriptome analysis of the early immune response in the lymph nodes of Borrelia burgdorferi-infected mice
    Varpu Rinne, Kirsi Gröndahl-Yli-Hannuksela, Ruth Fair-Mäkelä, Marko Salmi, Pia Rantakari, Tapio Lönnberg, Jukka Alinikula, Annukka Pietikäinen, Jukka HytönenMicrobes and Infection (2025)
    Core:Single Cell Omics
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