SHANK proteins limit integrin activation by directly interacting with Rap1 and R-Ras

Johanna Lilja, Thomas Zacharchenko, Maria Georgiadou, Guillaume Jacquemet, Nicola De Franceschi, Emilia Peuhu, Hellyeh Hamidi, Jeroen Pouwels, Victoria Martens, Fatemeh Hassani Nia, Malte Beifuss, Tobias Boeckers, Hans-Juergen Kreienkamp, Igor L. Barsukov, Johanna Ivaska

Nature Cell Biology (2017)

Published on December 4, 2025

DOI: https://doi.org/10.1038/ncb3487

Core: Advanced Imaging Core

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Genes associated with immune response are upregulated in clinically healthy skin of patients with gliptin-associated bullous pemphigoid

N. Kokkonen et al. • 2026 • Journal of Investigative Dermatology

Core:Finnish Functional Genomics Centre

Improving genotyped functional screening: A versatile closed-tube PCR for Illumina library generation reduces background sequences in multiplexed sequencing

S. Oksanen et al. • 2026 • SLAS Technology

Core:Finnish Functional Genomics Centre

Dynamic landscape of transcription initiation by yeast RNA polymerase I

O. Parilova et al. • 2026 • Nucleic Acids Research

Abstract RNA polymerase I (Pol I) synthesizes precursor ribosomal RNA, a key step in ribosome biogenesis. Elevated Pol I activity...

Core:Protein Structure and Chemistry

Staphylococcus aureus Augments Epithelial Skin Barrier Damage Through T Cell Activation in Cutaneous T Cell Lymphoma

M. Gluud et al. • 2026 • Allergy

ABSTRACT Background Skin barrier dysfunction is central to inflammation and susceptibility to infection in atopic dermatitis (AD). Cutaneous T‐cell lymphoma...

Core:Cytometry Core

Fast label-free live imaging with FlowVision reveals key principles of cancer cell arrest on endothelial monolayers

G. Follain et al. • 2026 • The EMBO Journal

Abstract The rapid, transient, and unpredictable nature of interactions between circulating cells and the endothelium challenges the investigation of these...

Core:Advanced Imaging Core

All user publications

SHANK proteins limit integrin activation by directly interacting with Rap1 and R-Ras

Genes associated with immune response are upregulated in clinically healthy skin of patients with gliptin-associated bullous pemphigoid

Improving genotyped functional screening: A versatile closed-tube PCR for Illumina library generation reduces background sequences in multiplexed sequencing

Dynamic landscape of transcription initiation by yeast RNA polymerase I

Staphylococcus aureus Augments Epithelial Skin Barrier Damage Through T Cell Activation in Cutaneous T Cell Lymphoma

Fast label-free live imaging with FlowVision reveals key principles of cancer cell arrest on endothelial monolayers

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Assembly of Bleomycin Saccharide-Decorated Spherical Nucleic Acids

Interaction of orally administered Lactobacillus rhamnosus GG with skin and gut microbiota and humoral immunity in infants with atopic dermatitis

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