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    Cytometry Core

    Selected publications

    Publications 2025

    Biological Evaluation of Molecular Spherical Nucleic Acids: Targeting Tumors via a Hybridization-Based Folate Decoration

    Core:Cytometry Core

    Tatsiana Auchynnikava, Antti Äärelä, Olli Moisio, Heidi Liljenbäck, Putri Andriana, Imran Iqbal, Toni Laine, Senthil Palani, Jyrki Lehtimäki, Johan Rajander, Harri Salo, Anu J. Airaksinen, Pasi Virta, Anne Roivainen
    ACS Omega (2025)
    https://doi.org/10.1021/acsomega.4c10047

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    Biomineralize Mitochondria in Metal‐Organic Frameworks to Promote Mitochondria Transplantation From Non‐Tumorigenic Cells Into Cancer Cells

    Core:Cytometry Core

    Jun‐Nian Zhou, Chang Liu, Yonghui Wang, Yong Guo, Xiao‐Yu Xu, Elina Vuorimaa‐Laukkanen, Oliver Koivisto, Anne M. Filppula, Jiangbin Ye, Hongbo Zhang
    Smart Medicine (2025)

    ABSTRACTMitochondria are crucial to cellular physiology, and growing evidence highlights the significant impact of mitochondrial dysfunction in diabetes, aging, neurodegenerative...
    https://doi.org/10.1002/smmd.134

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    COVID-19 vaccine type controls stromal reprogramming in draining lymph nodes

    Core:Cytometry Core

    Ruth Fair-Mäkelä, Pinja Thorén, Joni Näsiaho, Pia Sundqvist, Irina Piiroinen, Laura Kähäri, Ilkka Julkunen, Johanna Ivaska, Elin Hub, Antal Rot, Bishwa Ghimire, Jonna Alanko, Marko Salmi
    Science Immunology (2025)

    Lymph node (LN) stromal cells are critical regulators of immune reactions, yet their responses to different SARS-CoV-2 vaccines remain unexplored....
    https://doi.org/10.1126/sciimmunol.adr6787

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    Dynamic regulation of integrin β1 phosphorylation supports invasion of breast cancer cells

    Core:Cytometry Core

    James R. W. Conway, Omkar Joshi, Jasmin Kaivola, Gautier Follain, Michalis Gounis, David Kühl, Johanna Ivaska
    Nature Cell Biology (2025)

    Abstract Integrins provide an essential bridge between cancer cells and the extracellular matrix, playing a central role in every stage...
    https://doi.org/10.1038/s41556-025-01663-4

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    Early precursor-derived pituitary gland tissue-resident macrophages play a pivotal role in modulating hormonal balance

    Core:Cytometry Core

    Henna Lehtonen, Heli Jokela, Julian Hofmann, Lauriina Tola, Arfa Mehmood, Florent Ginhoux, Burkhard Becher, Melanie Greter, Gennady G. Yegutkin, Marko Salmi, Heidi Gerke, Pia Rantakari
    Cell Reports (2025)
    https://doi.org/10.1016/j.celrep.2024.115227

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    Enhanced antibody responses in CD19-Cre mice

    Core:Cytometry Core

    Diogo M. Cunha, Sara Hernández-Pérez, Pieta K. Mattila
    Scientific Reports (2025)
    https://doi.org/10.1038/s41598-024-83954-8

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    High-Resolution Imaging of Intracellular Trafficking of B Cell Receptor Using Specific Hybridization Internalization Probe (SHIP)

    Core:Cytometry Core

    Sara Hernández-Pérez, Pieta K. Mattila
    Methods in Molecular Biology (2025)
    https://doi.org/10.1007/978-1-0716-4442-3_6

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    Macrophage mannose receptor CD206-targeted PET imaging in experimental acute myocardial infarction

    Core:Cytometry Core

    Putri Andriana, Senthil Palani, Heidi Liljenbäck, Imran Iqbal, Vesa Oikonen, Jenni Virta, Konstantina Makrypidi, Johan Rajander, Erika Atencio Herre, Aino Suni, Sirpa Jalkanen, Juhani Knuuti, Luisa Martinez-Pomares, Ioannis Pirmettis, Xiang-Guo Li, Antti Saraste, Anne Roivainen
    EJNMMI Research (2025)

    Abstract Background The macrophage mannose receptor (CD206) is expressed predominantly on the surface of M2-type macrophages, which play a role...
    https://doi.org/10.1186/s13550-025-01254-2

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    Receptor stoichiometry predicts artery-typical vulnerability to altered Notch signaling during smooth muscle differentiation

    Core:Cytometry Core

    Sami Sanlidag, Noora Virtanen, Hesam Hoursan, Tommaso Ristori, Marika Sjöqvist, Sandra Loerakker, Cecilia Sahlgren
    2025

    ABSTRACT The development and maintenance of arterial smooth muscle cells (SMCs) rely on Jagged1-Notch2/Notch3 signaling. While Notch2 and Notch3 are...
    https://doi.org/10.1101/2025.05.05.652186

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    Secreted Clever-1 modulates T cell responses and impacts cancer immunotherapy efficacy

    Core:Cytometry Core

    Stuart Prince, Miro Viitala, Riikka Sjöroos, Ábris Á. Bendes, Jenna H. Rannikko, Daniel A. Patten, Ilaria di Benedetto, Rita Turpin, Arno Ylitalo, Laura Tyni, Carlos R. Figueiredo, Pia Boström, Ilkka Koskivuo, Tiina A. Salminen, Shishir Shetty, Maija Hollmén
    Theranostics (2025)
    https://doi.org/10.7150/thno.110544

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    Trajectories of microbiome-derived bile acids in early life – insights into the progression to islet autoimmunity

    Core:Cytometry Core

    Santosh Lamichhane, Alex M Dickens, Tanja Buchacher, Evita Tianai Lou, Vincent Charron-Lamoureux, Roosa Kattelus, Pragya Karmacharya, Lucas Pinto da Silva, Matilda Kråkström, Omid Rasool, Partho Sen, Corinn Walker, Abubaker Patan, Emily C. Gentry, Aron Arzoomand, Tadepally Lakshmikanth, Jaromir Mikeš, Aman Mebrahtu, Tommi Vatanen, Manuela Raffatellu, Karsten Zengler, Tuulia Hyötyläinen, Ramnik J. Xavier, Petter Brodin, Riitta Lahesmaa, Pieter C. Dorrestein, Mikael Knip, Matej Orešič
    2025

    Abstract Recent studies reveal that gut microbes produce diverse bile acid conjugates, termed microbially conjugated bile acids (MCBAs). However, their...
    https://doi.org/10.1101/2025.02.18.25322275

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    Last updated on February 4, 2026