Publications

The immune system has emerged as a critical factor influencing neurodevelopment in offspring. While this is increasingly well-studied in the context of maternal immune activation...

Colorectal cancer (CRC) patients with microsatellite-stable tumors typically resist immune checkpoint blockade (ICB) due to an immunosuppressive "cold" microenvironment. Photodynamic therapy (PDT) generates reactive oxygen...

Stress-generating therapeutic materials are commonly optimized to deliver cytotoxic inputs, but delivery alone does not determine whether intracellular stress becomes irreversible damage. Tumor cells can...

Multi-omics approaches have revolutionized our understanding of microbial communities by enabling simultaneous interrogation of genomic, transcriptomic, proteomic, and metabolomic data. The systematic integration and analysis...

CONCLUSIONS: Higher measured physical activity was inversely associated with detection of csPCa in men with suspicion of PCa. Active smoking also showed an inverse association....

Preprints have transformed how biologists share results, yet how well a preprint reads still depends on formatting, a task that has shifted from publishers to...

Cancer cells utilize filopodia to explore, adhere to, and invade their surrounding microenvironment, yet the protein networks that organize these protrusions remain incompletely defined. To...

In the process of mounting humoral immune responses, B cells typically engage antigens on the surface of antigen-presenting cells (APCs) via the immunological synapse (IS)....

Per- and polyfluoroalkyl substances (PFAS) are persistent environmental contaminants that can disrupt human hepatic metabolism both directly and through alterations of the gut microbiota. However,...

Regulatory T cells (Treg) play a central role in maintaining immune homeostasis, and the implementation of in vitro induced Treg cells (iTreg) to control immune...

Cancer-induced bone osteolysis is a common complication of multiple malignancies and may actively contribute to bone metastasis. Its core pathology is closely associated with mitochondrial...

Integrating tissue-level organisation with sub-cellular resolution and molecular information often requires combining multiple microscopy modalities and scales. However, aligning images acquired with different modalities, settings,...