Publications

    All Publications (242)

    Trajectories of microbiome-derived bile acids in early life – insights into the progression to islet autoimmunity 
    Santosh Lamichhane et al. medRxiv [Preprint]. 2025 Feb 24:2025.02.18.25322275. doi: 10.1101/2025.02.18.25322275. Published March 10, 2025
    Recent studies reveal that gut microbes produce diverse bile acid conjugates, termed microbially conjugated bile acids (MCBAs). However, their regulation and health effects remain unclear....
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    Multifunctional Silk and Gelatin Composed Microneedle Patches for Enhanced Wound Healing 
    Lu Fan et al. Smart Med. 2025 Feb 26;4(1):e137. doi: 10.1002/smmd.137. eCollection 2025 Mar. Published March 10, 2025
    Wound healing has been a continuous critical focus in clinical practice, posing the ongoing challenges and burdens to patients. Current attempts tend to develop multi-drug...
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    Biomineralize Mitochondria in Metal-Organic Frameworks to Promote Mitochondria Transplantation From Non-Tumorigenic Cells Into Cancer Cells 
    Jun-Nian Zhou et al. Smart Med. 2025 Feb 26;4(1):e134. doi: 10.1002/smmd.134. eCollection 2025 Mar. Published March 10, 2025
    Mitochondria are crucial to cellular physiology, and growing evidence highlights the significant impact of mitochondrial dysfunction in diabetes, aging, neurodegenerative disorders, and cancers. Therefore, mitochondrial...
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    Risk of early death after treatment with curative intent for head and neck squamous cell carcinoma: a retrospective population-based study 
    Mahmoud Bazina et al. Acta Oncol. 2025 Mar 4;64:339-348. doi: 10.2340/1651-226X.2025.42202. Published March 4, 2025
    BACKGROUND AND PURPOSE: Knowledge regarding the risk factors for early death in patients with head and neck squamous cell carcinoma (HNSCC) is scarce. This study...
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    A new rapid lipoarabinomannan urine assay for tuberculosis: a two-centre diagnostic accuracy evaluation in outpatients with and without HIV 
    Beston Hamasur et al. Res Sq [Preprint]. 2025 Feb 18:rs.3.rs-5386988. doi: 10.21203/rs.3.rs-5386988/v2. Published March 4, 2025
    CONCLUSIONS: BP-LAM has higher sensitivity than LF-LAM, including in HIV-negative people, potentially permitting the expansion of urine LAM testing beyond people with advanced immunosuppression.
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    Targeted serum proteomics of longitudinal samples from newly diagnosed youth with type 1 diabetes affirms markers of disease 
    Robert Moulder et al. Diabetologia. 2025 Jun;68(6):1108-1114. doi: 10.1007/s00125-025-06394-7. Epub 2025 Feb 28. Published February 28, 2025
    CONCLUSIONS/INTERPRETATION: The validated results reflect the landscape of biological changes accompanying type 1 diabetes. For example, the association of the targeted apolipoproteins with fasting C-peptide/glucose...
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    Added value of HPV-DNA <em>in situ</em> hybridization as an adjunct to p16 Immunohistochemistry in oropharyngeal squamous cell carcinoma 
    Linda Nissi et al. Acta Otolaryngol. 2025 Apr;145(4):340-347. doi: 10.1080/00016489.2025.2461653. Epub 2025 Feb 10. Published February 10, 2025
    CONCLUSIONS AND SIGNIFICANCE: Both p16 IHC and HPV-DNA ISH perform well as separate prognostic biomarkers for OS, DSS, and DFS on a population level. However,...
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    Exploring the physicochemical interactions and loading strategies of mesoporous silicon dioxide nanoparticles for drug delivery 
    Svetlana Yu Kovtareva et al. Eur J Pharm Biopharm. 2025 Mar;208:114654. doi: 10.1016/j.ejpb.2025.114654. Epub 2025 Feb 3. Published February 5, 2025
    Mesoporous silica nanoparticles play an important role in drug delivery due to their high surface area, porous structure, tunable pore size, chemical stability and functionalization...
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    Nuclear talin-1 provides a bridge between cell adhesion and gene expression 
    Alejandro J Da Silva et al. iScience. 2025 Jan 4;28(2):111745. doi: 10.1016/j.isci.2025.111745. eCollection 2025 Feb 21. Published February 3, 2025
    Talin-1 (TLN1) is best known to activate integrin receptors and transmit mechanical stimuli to the actin cytoskeleton at focal adhesions. However, the localization of TLN1...
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    Liquid and gas-chromatography-mass spectrometry methods for exposome analysis 
    Victor Castro-Alves et al. J Chromatogr A. 2025 Mar 15;1744:465728. doi: 10.1016/j.chroma.2025.465728. Epub 2025 Jan 25. Published February 2, 2025
    Mass spectrometry-based methods have become fundamental to exposome research, providing the capability to explore a broad spectrum of chemical exposures. Liquid and gas chromatography coupled...
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    Metaproteomics Beyond Databases: Addressing the Challenges and Potentials of De Novo Sequencing 
    Tim Van Den Bossche et al. Proteomics. 2025 Jan 31:e202400321. doi: 10.1002/pmic.202400321. Online ahead of print. Published January 31, 2025
    Metaproteomics enables the large-scale characterization of microbial community proteins, offering crucial insights into their taxonomic composition, functional activities, and interactions within their environments. By directly...
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    Adaptive sequence alignment for metagenomic data analysis 
    Sami Pietilä et al. Comput Biol Med. 2025 Mar;186:109743. doi: 10.1016/j.compbiomed.2025.109743. Epub 2025 Jan 26. Published January 27, 2025
    With advances in sequencing technologies, the use of high-throughput sequencing to characterize microbial communities is becoming increasingly feasible. However, metagenomic assembly poses computational challenges in...
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