In this study, we investigated the impact of bariatric surgery on the adipose proteome to better understand the metabolic and cellular mechanisms underlying weight loss following the procedure. A total…
There Goes the Neighbourhood-A Multi-City Study Reveals Ticks and Tick-Borne Pathogens Commonly Occupy Urban Green Spaces
CONCLUSIONS: Ticks and TBPs are commonplace in urban green spaces in Finland. Enzootic cycles for Borrelia and Rickettsia appear to be well maintained within cities, leading to widespread risk of…
Microfluidics-enabled core/shell nanostructure assembly: Understanding encapsulation processes via particle characterization and molecular dynamics
In the realm of hybrid nanomaterials, the construction of core/shell nanoparticles offer an effective strategy for encompassing a particle by a polymeric or other suitable material, leading to a nanocomposite…
Efficiently accelerated bioimage analysis with NanoPyx, a Liquid Engine-powered Python framework
The expanding scale and complexity of microscopy image datasets require accelerated analytical workflows. NanoPyx meets this need through an adaptive framework enhanced for high-speed analysis. At the core of NanoPyx,…
Harnessing artificial intelligence to reduce phototoxicity in live imaging
Fluorescence microscopy is essential for studying living cells, tissues and organisms. However, the fluorescent light that switches on fluorescent molecules also harms the samples, jeopardizing the validity of results -…
AXL-TBK1 driven AKT3 activation promotes metastasis
The receptor tyrosine kinase AXL promotes tumor progression, metastasis, and therapy resistance through the induction of epithelial-mesenchymal transition (EMT). Here, we found that activation of AXL resulted in the phosphorylation…
Engineering and Targeting Neutrophils for Cancer Therapy
Neutrophils are the most abundant white blood cells in the circulation and act as the first line of defense against infections. Increasing evidence suggests that neutrophils possess heterogeneous phenotypes and…
Stress biology: Complexity and multifariousness in health and disease
Preserving and regulating cellular homeostasis in the light of changing environmental conditions or developmental processes is of pivotal importance for single cellular and multicellular organisms alike. To counteract an imbalance…
Embigin deficiency leads to delayed embryonic lung development and high neonatal mortality in mice
Embigin (Gp70), a receptor for fibronectin and an ancillary protein for monocarboxylate transporters, is known to regulate stem cell niches in sebaceous gland and bone marrow. Here, we show that…
Cancer Foundation Finland funding to Turku Bioscience Research Groups
We’re excited to share fantastic funding news! Cancer Foundation Finland has awarded grants to several research groups at Turku Bioscience. In 2024, the foundation allocated a record-breaking total of over…