Frontiers of Science seminar program is ready for autumn 2024. All seminars are on-site only at 12:00. Coffee and sandwich are served before each seminar. Frontiers of Science…
Intermediate filaments at a glance
Intermediate filaments (IFs) comprise a large family of versatile cytoskeletal proteins, divided into six subtypes with tissue-specific expression patterns. IFs have a wide repertoire of cellular functions, including providing structural…
Emerging ctDNA detection strategies in clinical cancer theranostics
Circulating tumor DNA (ctDNA) is naked DNA molecules shed from the tumor cells into the peripheral blood circulation. They contain tumor-specific gene mutations and other valuable information. ctDNA is considered…
Iron-doped nanozymes with spontaneous peroxidase-mimic activity as a promising antibacterial therapy for bacterial keratitis
The development of non-antibiotic pharmaceuticals with biocompatible and efficient antibacterial properties is of great significance for the treatment of bacterial keratitis. In this study, we have developed antibacterial iron-doped nanozymes…
Novel coumarin-6-sulfonamide-chalcone hybrids as glutathione transferase P1-1 inhibitors
Multidrug resistance (MDR) mechanisms in cancer cells are greatly influenced by glutathione transferase P1-1 (hGSTP1-1). The use of synthetic or natural compounds as hGSTP1-1 inhibitors is considered an effective approach…
7.8 Euros MEUR of Horizon Europe funding to Cecilia Sahlgren and Hongbo Zhang
The NAP4DIVE project of TBC group leaders Cecilia Sahlgren and Hongbo Zhang were awarded 7.8 MEUR of Horizon Europe funding (Total 7.8 million euro, ÅAU cut 2.4 million euro).
Turku Bioscience Centre researchers founded a cancer diagnostics start-up company
Modern cancer treatment aims for the most effective treatment possible, which would cause the patients as few side effects as possible. The individual choice of treatment for each patient, however,…
CellTracksColab is a platform that enables compilation, analysis, and exploration of cell tracking data
In life sciences, tracking objects from movies enables researchers to quantify the behavior of single particles, organelles, bacteria, cells, and even whole animals. While numerous tools now allow automated tracking…
Utilizing Macrophages Missile for Sulfate-Based Nanomedicine Delivery in Lung Cancer Therapy
Nanomaterial-based drug delivery systems are susceptible to premature drug leakage and systemic toxicity due to lack of specific targeting, and live-cell drug delivery is also prone to be restricted by…
Synaptic proteome perturbations after maternal immune activation: Identification of embryonic and adult hippocampal changes
CONCLUSIONS: Our data emphasise the dynamic effects of viral-like MIA on developing and mature hippocampi and provide novel targets for study following prenatal immune challenges. The 22 proteins that changed…