Event Details

InFLAMES Visiting Professor Seminar by Mark Ansel

Time: 12.10.2026  at 11-12

Place: Arje Scheinin auditorium, Dentalia building

Mark Ansel, University of California San Francisco (UCSF), US: Cellular and molecular regulation of Th2 inflammation in the airways and other barrier tissues

Coffee is served at 10.30

Host: Riitta Lahesmaa ( rilahes @ utu.fi )

Professor Mark Ansel‘s research group at the University of California, San Francisco, studies the molecular regulation of immune responses that underlie the pathology of inflammatory diseases, with a focus on T cell programming and cytokine genes. They conduct fundamental research on RNA regulation of the immune system. In addition, they collaborate closely with physician scientists, technologists and data scientists to conduct mechanism-oriented human immunology research. Mark Ansel is a co-founder and current Chair of the UCSF Bakar ImmunoX Initiative and an active affiliate of the Sandler Asthma Basic Research Center, the Gladstone-UCSF Institute of Genomic Immunology and the UCSF Diabetes Center. ImmunoX and its UCSF Co-Labs provide access to technology platforms and domain experts using a novel collaborative structure and funding model that connects teams of scientists with clinical, biological, technological and computational expertise to maximize the impact of their research program in human immunology.

Selected publications:

Fassett MS, Braz JM, Castellanos CA, Salvatierra JJ, Sadeghi M, Yu X, Schroeder AW, Caston J, Munoz-Sandoval P, Roy S, Lazarevsky S, Mar DJ, Zhou CJ, Shin JS, Basbaum AI, Ansel KM. IL-31-dependent neurogenic inflammation restrains cutaneous type 2 immune response in allergic dermatitis. Sci Immunol. 2023 Oct 20;8(88):eabi6887. doi: 10.1126/sciimmunol.abi6887. Epub 2023 Oct 13. PMID: 37831760; PMCID: PMC10890830.

Siddiqui S, Johansson K, Joo A, Bonser LR, Koh KD, Le Tonqueze O, Bolourchi S, Bautista RA, Zlock L, Roth TL, Marson A, Bhakta NR, Ansel KM, Finkbeiner WE, Erle DJ, Woodruff PG. Epithelial miR-141 regulates IL-13-induced airway mucus production. JCI Insight. 2021 Mar 8;6(5):e139019. doi: 10.1172/jci.insight.139019. PMID: 33682796; PMCID: PMC8021117.

Wheeler BD, Wang J, Nerella S, Johansson K, Garudadri S, Muñoz-Sandoval P, Mazumder T, Christenson SA, Bhakta NR, Erle DJ, Ansel KM, Woodruff PG. Allergen-responsive T helper type 2 cells revealed by high-dimensional profiling in allergen challenged human airways. bioRxiv [Preprint]. 2026 Aug 6:2026.07.31.741782. doi: 10.64898/2026.07.31.741782. PMID: 42620144; PMCID: PMC13484523.