Updates

Immunology Seminar

May 3rd at 14:00 – 15:00

Virtual event

Ludvig Sollid, Institute of Clinical Medicine and KG Jebsen Coeliac Disease Research Centre, University of Oslo and Department of Immunology, Oslo University Hospital: “Triggers and drivers of autoimmunity”

Registration latest May 2 at: https://link.webropolsurveys.com/S/E8E36C4960A8B012

Zoom link and iCalendar invitation to join the online event will be sent to all registered participants one day before the event.

Immunology seminar series is jointly organised by the Finnish Society for Immunology, InFLAMES Flagship and Turku Bioscience. For further information contact Anne Lahdenperä ( ankahy@utu.fi ) or Riitta Lahesmaa ( rilahes@utu.fi ), University of Turku.

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Ludvig M. Sollid (MD, PhD) is a Professor at the University of Oslo and a Senior Consultant at the Oslo University Hospital – Rikshospitalet. He is also the Director of the KG Jebsen Coeliac Disease Research Centre and UiO FOCIS Centre of Excellence. His research interests are focused around genetics and immunology of autoimmune diseases.

His group has made important contributions to the understanding of the molecular basis of coeliac disease, in particular the role of HLA genes, the existence of gluten reactive (HLA-DQ restricted) T cells in the coeliac intestinal lesion, the identification of immunotoxic gluten peptide sequences and the involvement of the transglutaminase 2 in the pathogenesis of the disease. His group is currently working on the characterization of the antigen receptors of T cells and B cells that recognize the coeliac disease relevant antigens gluten and transglutaminase 2.

Sollid is the recipient of several research awards including the Research Council of Norway’s Møbius Prize for Outstanding Research, the Warren Prize for Excellence in Celiac Disease Research, the Rank Prize in Nutrition, the UEG Research Prize and the Jahre Medical Prize (junior award 1998 and senior award (2015). He currently serves on the editorial boards of Mucosal Immunology, Scandinavian Journal of Immunology, Tissue Antigens, Genes and Immunity and Gastroenterology.

Selected publications:

Ludvig M Sollid, Bana Jabri. Triggers and drivers of autoimmunity: lessons from coeliac disease. Nat Rev Immunol 13:294-302, 2013.

Ludvig M Sollid. Epstein-Barr virus as a driver of multiple sclerosis. Sci Immunol. 7:eabo7799, 2022.

Roberto Di Niro, Luka Mesin, Nai-Ying Zheng, Jorunn Stamnaes, Michael Morrissey, Jane-Hwei Lee, Min Huang, Rasmus Iversen, M Fleur du Pré, Shuo-Wang Qiao, Knut E A Lundin, Patrick C Wilson, Ludvig M Sollid.

High abundance of plasma cells secreting transglutaminase 2-specific IgA autoantibodies with limited somatic hypermutation in celiac disease intestinal lesions. Nat Med 18:441-5, 2012.

Asbjørn Christophersen, Eivind G Lund, Omri Snir, Elsa Solà, Chakravarthi Kanduri, Shiva Dahal-Koirala, Stephanie Zühlke, Øyvind Molberg, Paul J Utz, Mina Rohani-Pichavant, Julia F Simard, Cornelia L Dekker, Knut E A Lundin, Ludvig M Sollid, Mark M Davis. Distinct phenotype of CD4 + T cells driving celiac disease identified in multiple autoimmune conditions. Nat Med 25:734-737, 2019.

M Fleur du Pré, Jana Blazevski, Alisa E Dewan, Jorunn Stamnaes, Chakravarthi Kanduri, Geir Kjetil Sandve, Marie K Johannesen, Christian B Lindstad, Kathrin Hnida, Lars Fugger, Gerry Melino, Shuo-Wang Qiao, Ludvig M Sollid. B cell tolerance and antibody production to the celiac disease autoantigen transglutaminase 2. J Exp Med 217:e20190860, 2020.