João Marcos G Barbosa et al.Environ Int. 2026 May 29;213:110337. doi: 10.1016/j.envint.2026.110337. Online ahead of print.Published May 30, 2026
Per- and polyfluoroalkyl substances (PFAS) are highly persistent environmental pollutants that bioaccumulate in living organisms and are increasingly implicated in metabolic dysfunction-associated steatotic liver disease... Read more
Angelica P Ahrens et al.mSystems. 2026 May 28:e0142425. doi: 10.1128/msystems.01424-25. Online ahead of print.Published May 28, 2026
Childhood obesity is rising globally. Yet, few studies have examined the microbiome and proteome in early childhood in relation to this outcome, and most are... Read more
Tomi Suomi et al.Bioinformatics. 2026 May 22:btag335. doi: 10.1093/bioinformatics/btag335. Online ahead of print.Published May 24, 2026
SUMMARY: Recently, Anwar et al. introduced a method combining the ROTS reproducibility optimisation procedure with empirical Bayes variance estimation from limma. Here, we clarify several... Read more
Wei Ba et al.Curr Biol. 2026 May 19:S0960-9822(26)00529-4. doi: 10.1016/j.cub.2026.04.059. Online ahead of print.Published May 20, 2026
How the brain compensates for sleep deprivation (SD) by generating recovery sleep (RS) is not understood. Using Ca²⁺ photometry, we identified a WAKE/rapid eye movement... Read more
Markus Lindén et al.Protein Sci. 2026 Jun;35(6):e70621. doi: 10.1002/pro.70621.Published May 18, 2026
Biomedical studies increasingly incorporate longitudinal data, enabling us to track individual disease processes over time at the molecular level, and to discover associations of the... Read more
Venla Huovinen et al.Dev Psychopathol. 2026 May 8:1-15. doi: 10.1017/S0954579426101527. Online ahead of print.Published May 8, 2026
CONCLUSIONS: Alpha diversity in infancy was negatively associated with preschool EF. Additionally, EFs differed between microbial groups based on dominant genera. Bacterial genera abundances were... Read more
Mona M Wang et al.Commun Biol. 2026 May 5. doi: 10.1038/s42003-026-10118-x. Online ahead of print.Published May 5, 2026
BAP1-deficient melanocytic tumors exhibit strong immunosuppressive features and poor prognosis. Currently, no immune-competent preclinical models exist to study their tumor-immune interactions or test new immunotherapies.... Read more
Wu Yang et al.Biomaterials. 2026 Apr 28;334:124255. doi: 10.1016/j.biomaterials.2026.124255. Online ahead of print.Published May 5, 2026
Effective bone healing is accompanied by coupled osteogenic-angiogenic regeneration, a process that critically depends on metabolic communication between bone marrow mesenchymal stem cells (BMSCs) and... Read more
James T Grist et al.J Neuroinflammation. 2026 May 4. doi: 10.1186/s12974-026-03839-7. Online ahead of print.Published May 4, 2026
Given the prevalence of metabolic perturbations in a variety of neurological and neurodegenerative diseases, understanding and monitoring brain metabolism is a key step in our... Read more
Yu Zhang et al.Smart Med. 2026 Mar 30;5(2):e70031. doi: 10.1002/smmd.70031. eCollection 2026 Apr.Published May 4, 2026
Although chemotherapy-induced bone loss is well-recognized during breast cancer treatment, the underlying mechanism remains to be further elucidated, especially in patients with obesity. In this... Read more
Markus Lindén et al.Bioinformatics. 2026 May 4:btag203. doi: 10.1093/bioinformatics/btag203. Online ahead of print.Published May 4, 2026
SUMMARY: We introduce REACTOR, a computational tool designed to detect differential activity of transcriptional regulators and their target genes (regulons) in single-cell RNA-sequencing data. It... Read more
Amy E M Beedle et al.Nat Mater. 2026 Apr 29. doi: 10.1038/s41563-026-02590-x. Online ahead of print.Published April 29, 2026
The cell nucleus is continuously exposed to external signals, of both chemical and mechanical nature. To ensure proper cellular response, cells need to regulate the... Read more
