Publications

    All Publications (240)

    Utilizing Macrophages Missile for Sulfate-Based Nanomedicine Delivery in Lung Cancer Therapy 
    Chang Liu et al. Research (Wash D C). 2024 Aug 6;7:0448. doi: 10.34133/research.0448. eCollection 2024. Published August 7, 2024
    Nanomaterial-based drug delivery systems are susceptible to premature drug leakage and systemic toxicity due to lack of specific targeting, and live-cell drug delivery is also...
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    Gene Regulatory Network Analysis of Decidual Stromal Cells and Natural Killer Cells 
    Kalle T Rytkönen et al. Reprod Sci. 2024 Oct;31(10):3159-3174. doi: 10.1007/s43032-024-01653-1. Epub 2024 Aug 1. Published August 1, 2024
    Human reproductive success relies on the proper differentiation of the uterine endometrium to facilitate implantation, formation of the placenta, and pregnancy. This process involves two...
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    Synaptic proteome perturbations after maternal immune activation: Identification of embryonic and adult hippocampal changes 
    Anna Y Yotova et al. Brain Behav Immun. 2024 Oct;121:351-364. doi: 10.1016/j.bbi.2024.07.040. Epub 2024 Jul 31. Published August 1, 2024
    CONCLUSIONS: Our data emphasise the dynamic effects of viral-like MIA on developing and mature hippocampi and provide novel targets for study following prenatal immune challenges....
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    Inferring Tree-Shaped Single-Cell Trajectories with Totem 
    António G G Sousa et al. Methods Mol Biol. 2024;2812:169-191. doi: 10.1007/978-1-0716-3886-6_9. Published July 27, 2024
    Single-cell transcriptomics allows unbiased characterization of cell heterogeneity in a sample by profiling gene expression at single-cell level. These profiles capture snapshots of transient or...
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    HSV-1 and Cellular miRNAs in CSF-Derived Exosomes as Diagnostically Relevant Biomarkers for Neuroinflammation 
    Christian Scheiber et al. Cells. 2024 Jul 17;13(14):1208. doi: 10.3390/cells13141208. Published July 26, 2024
    Virus-associated chronic inflammation may contribute to autoimmunity in a number of diseases. In the brain, autoimmune encephalitis appears related to fluctuating reactivation states of neurotropic...
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    The PP2A regulator IER5L supports prostate cancer progression 
    Jana R Crespo et al. Cell Death Dis. 2024 Jul 18;15(7):514. doi: 10.1038/s41419-024-06907-z. Published July 18, 2024
    Prostate cancer exhibits high prevalence and accounts for a high number of cancer-related deaths. The discovery and characterization of molecular determinants of aggressive prostate cancer...
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    Protocol to study early lung developmental branching in mouse embryos using explant culture 
    Salli Talvi et al. STAR Protoc. 2024 Sep 20;5(3):103198. doi: 10.1016/j.xpro.2024.103198. Epub 2024 Jul 17. Published July 18, 2024
    Mouse lung branching morphogenesis creates epithelial tree structures required for respiration. Here, we present a protocol for studying mouse lung developmental branching using lung explant...
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    TLNRD1 is a CCM complex component and regulates endothelial barrier integrity 
    Neil J Ball et al. J Cell Biol. 2024 Sep 2;223(9):e202310030. doi: 10.1083/jcb.202310030. Epub 2024 Jul 16. Published July 16, 2024
    We previously identified talin rod domain-containing protein 1 (TLNRD1) as a potent actin-bundling protein in vitro. Here, we report that TLNRD1 is expressed in the...
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    Identification of an H-Ras nanocluster disrupting peptide 
    Candy Laura Steffen et al. Commun Biol. 2024 Jul 9;7(1):837. doi: 10.1038/s42003-024-06523-9. Published July 9, 2024
    Hyperactive Ras signalling is found in most cancers. Ras proteins are only active in membrane nanoclusters, which are therefore potential drug targets. We previously showed...
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    Body-wide genetic deficiency of poly(ADP-ribose) polymerase 14 sensitizes mice to colitis 
    Madhukar Vedantham et al. FASEB J. 2024 Jul 15;38(13):e23775. doi: 10.1096/fj.202400484R. Published July 5, 2024
    Inflammatory bowel disease (IBD) is a chronic disease of the gastrointestinal tract affecting millions of people. Here, we investigated the expression and functions of poly(ADP-ribose)...
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    Multi-omics analysis reveals drivers of loss of β-cell function after newly diagnosed autoimmune type 1 diabetes: An INNODIA multicenter study 
    Jose Juan Almagro Armenteros et al. Diabetes Metab Res Rev. 2024 Jul;40(5):e3833. doi: 10.1002/dmrr.3833. Published July 4, 2024
    CONCLUSIONS: Features that differ between individuals with slow and rapid decline in β-cell mass could be valuable in staging and prediction of the rate of...
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    Cancer cell invasion alters the protein profile of extracellular vesicles 
    Jens C Luoto et al. J Extracell Biol. 2023 Nov 27;2(12):e124. doi: 10.1002/jex2.124. eCollection 2023 Dec. Published June 28, 2024
    Extracellular vesicles (EVs) are important mediators of intercellular communication involved in local and long-range signalling of cancer metastasis. The onset of invasion is the key...
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