Researchers Identify Gene Expression Signature That Predicts Progression of Type 1 Diabetes
The study led by Professor Laura Elo and Professor Riitta Lahesmaa aimed to identify transcriptional changes associated with disease progression in patients with recent-onset type 1 diabetes.
The researchers analysed blood samples collected as part of the global INNODIA partnership. A certain gene expression signature was found to be associated with rapid disease progression.
“One benefit of such predictive signature would be the ability to intervene earlier in the disease process. This could help slow the progression of the disease and potentially prevent or delay the onset of symptoms. Another benefit would be improved monitoring of the disease progression, which would allow for more personalised treatment plans and better outcomes for patients”, Elo and Lahesmaa explain.
Type 1 diabetes is a complex autoimmune disease where insulin-producing beta cells in the pancreas are destroyed. Disease progression varies between individuals and currently there is no way to predict individual outcomes. >> Keep reading
In addition to Riitta Lahesmaa and Laura Elo, the first authors of the article included (from left) Senior Researher Ubaid Kalim, Postdoctoral Researcher Tomi Suomi and Doctoral Researcher Inna Starskaia.
Kuvaaja/Tekijä
Liisa Koivula
Recent Posts
- Participate to Open Hardware Workshop, sign up now! Access to research hardware remains a global challenge and it impacts also researchers in high-income Read moreNovember 3, 2025
- The Academy of Finland granted Johanna Ivaska €2,400,000 in funding for an Academy Professor position The Academy of Finland granted our Group Leader, Professor Johanna Ivaska €2,400,000 in funding for Read moreOctober 30, 2025
- Guillaume Jacquemet and Cecilia Sahlgren receive funding for the Research Council of Finland Centre of Excellence in Immune-Endothelial Interactions (IMMENs) Associate Professor Guillaume Jacquemet, our Group Leader, and Professor Cecilia Sahlgren, our affiliated Group Leader, Read moreOctober 30, 2025
- Registration to AI2Med imaging event is now open! Registration for AI2Med Turku 2025 is open! The event is organized by the Turku PET Read moreOctober 21, 2025
- Jonna Alanko receives the Young Investigator Award from the Scandinavian Society for Immunology Jonna Alanko has received the Young Investigator Award of the Scandinavian Society for Immunology. The Read moreOctober 17, 2025
- Professor Riitta Lahesmaa awarded Johnny Ludvigsson Prize for Outstanding Nordic Researcher Professor Riitta Lahesmaa was awarded Johnny Ludvigsson Prize for Outstanding Nordic Researcher. The prize is Read moreOctober 16, 2025