IMMUNOCAPs Visiting Professor Seminar by Professor O’Neill
When
Event Details
Professor Luke O’Neill, Trinity College Dublin, Ireland: Prospects for new anti-inflammatory therapeutics that target immunometabolism.
Host: Cecilia Söderberg-Nauclér ( cecilia.naucler (at) utu.fi )
The seminar is open to everyone.
Coffee and tea is served before the seminar from 14:00 onwards.
About the speaker:
Luke O’Neill is Professor of Biochemistry in the School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute at Trinity College Dublin, Ireland. He is a world expert on innate immunity and inflammation. He is listed by Thompson Reuters/ Clarivates in the top 1% of immunologists in the world, based on citations per paper. Professor O’Neill is a co-founder of Sitryx, which aims to develop new medicines for inflammatory diseases. Another company he co-founded, Inflazome was acquired by Roche in 2020 and is carrying out trials in Parkinson’s Disease, Severe Asthma and Heart disease using new therapeutics based on his work.
Luke has a weekly science slot with Pat Kenny on Newstalk and a weekly column on science in the Sunday Independent. He has published several books including Humanology: A Scientist’s Guide to our Amazing Existence, The Great Irish Science Book, Never Mind the B*ll*cks, Here’s the Science (which won the An Post prize for best popular non-fiction book). In 2021 he published Keep Calm and Trust the Science: A Remarkable Year in the Life of an Immunologist, which is his diary covering the COVID-19 pandemic. In 2023 he published To Boldly Go Where No Book has Gone Before, with Penguin Random House. His books have been translated into 8 languages.
Selected publications:
- Carpenter S, O’Neill LAJ. From periphery to center stage: 50 years of advancements in innate immunity. Cell. 2024 Apr 25;187(9):2030-2051. doi: 10.1016/j.cell.2024.03.036.
- Murphy MP, O’Neill LAJ.A break in mitochondrial endosymbiosis as a basis for inflammatory diseases. Nature (2024) Feb;626(7998):271-279. doi: 10.1038/s41586-023-06866-z. Epub 2024 Feb 7.
- Pålsson-McDermott EM, O’Neill LAJ Gang of 3: How the Krebs cycle-linked metabolites itaconate, succinate, and fumarate regulate macrophages and inflammation. Cell Metab. 2025 May 6;37(5):1049-1059. doi: 10.1016/j.cmet.2025.03.004
