Publications

    PUBLICATION

    Serum lipidome associates with neuroimaging features in patients with traumatic brain injury 

    Ilias Thomas et al.

    iScience. 2024 Aug 3;27(9):110654. doi: 10.1016/j.isci.2024.110654. eCollection 2024 Sep 20.

    Published on September 10, 2024

    Acute traumatic brain injury (TBI) is associated with substantial abnormalities in lipid biology, including changes in the structural lipids that are present in the myelin Read more

    PUBLICATION

    Disruption of HSD17B12 in mouse hepatocytes leads to reduced body weight and defect in the lipid droplet expansion associated with microvesicular steatosis 

    Hanna Heikelä et al.

    FASEB J. 2024 Sep 15;38(17):e70034. doi: 10.1096/fj.202400333RR.

    Published on September 9, 2024

    The function of hydroxysteroid dehydrogenase 12 (HSD17B12) in lipid metabolism is poorly understood. To study this further, we created mice with hepatocyte-specific knockout of HSD17B12 Read more

    PUBLICATION

    Lower Plasma Levels of Selective VGF (Non-Acronymic) Peptides in Bipolar Disorder: Comparative Analysis Reveals Distinct Patterns across Mood Disorders and Healthy Controls 

    Cristina Cocco et al.

    Neuropsychobiology. 2024;83(3-4):160-169. doi: 10.1159/000540673. Epub 2024 Sep 6.

    Published on September 8, 2024

    CONCLUSION: Our findings suggest that lower plasma levels of NAPP and AQEE are specifically associated with BD, thus possibly representing a diagnostic biomarker in mood Read more

    PUBLICATION

    ECCB2024: The 23rd European Conference on Computational Biology 

    Anu Kukkonen-Macchi et al.

    Bioinformatics. 2024 Sep 1;40(Suppl 2):ii1-ii3. doi: 10.1093/bioinformatics/btae422.

    Published on September 4, 2024

    No abstract

    PUBLICATION

    Intermediate filaments at a glance 

    Leila S Coelho-Rato et al.

    J Cell Sci. 2024 Aug 15;137(16):jcs261386. doi: 10.1242/jcs.261386. Epub 2024 Aug 29.

    Published on August 29, 2024

    Intermediate filaments (IFs) comprise a large family of versatile cytoskeletal proteins, divided into six subtypes with tissue-specific expression patterns. IFs have a wide repertoire of Read more

    PUBLICATION

    Iron-doped nanozymes with spontaneous peroxidase-mimic activity as a promising antibacterial therapy for bacterial keratitis 

    Xiwen Geng et al.

    Smart Med. 2024 May 22;3(2):e20240004. doi: 10.1002/SMMD.20240004. eCollection 2024 Jun.

    Published on August 27, 2024

    The development of non-antibiotic pharmaceuticals with biocompatible and efficient antibacterial properties is of great significance for the treatment of bacterial keratitis. In this study, we Read more

    PUBLICATION

    Emerging ctDNA detection strategies in clinical cancer theranostics 

    Kexin Yi et al.

    Smart Med. 2023 Nov 13;2(4):e20230031. doi: 10.1002/SMMD.20230031. eCollection 2023 Nov.

    Published on August 27, 2024

    Circulating tumor DNA (ctDNA) is naked DNA molecules shed from the tumor cells into the peripheral blood circulation. They contain tumor-specific gene mutations and other Read more

    PUBLICATION

    Novel coumarin-6-sulfonamide-chalcone hybrids as glutathione transferase P1-1 inhibitors 

    Ahmed Sabt et al.

    PLoS One. 2024 Aug 14;19(8):e0306124. doi: 10.1371/journal.pone.0306124. eCollection 2024.

    Published on August 14, 2024

    Multidrug resistance (MDR) mechanisms in cancer cells are greatly influenced by glutathione transferase P1-1 (hGSTP1-1). The use of synthetic or natural compounds as hGSTP1-1 inhibitors Read more

    PUBLICATION

    CellTracksColab is a platform that enables compilation, analysis, and exploration of cell tracking data 

    Estibaliz Gómez-de-Mariscal et al.

    PLoS Biol. 2024 Aug 8;22(8):e3002740. doi: 10.1371/journal.pbio.3002740. eCollection 2024 Aug.

    Published on August 8, 2024

    In life sciences, tracking objects from movies enables researchers to quantify the behavior of single particles, organelles, bacteria, cells, and even whole animals. While numerous Read more

    PUBLICATION

    Utilizing Macrophages Missile for Sulfate-Based Nanomedicine Delivery in Lung Cancer Therapy 

    Chang Liu et al.

    Research (Wash D C). 2024 Aug 6;7:0448. doi: 10.34133/research.0448. eCollection 2024.

    Published on August 7, 2024

    Nanomaterial-based drug delivery systems are susceptible to premature drug leakage and systemic toxicity due to lack of specific targeting, and live-cell drug delivery is also Read more

    PUBLICATION

    Gene Regulatory Network Analysis of Decidual Stromal Cells and Natural Killer Cells 

    Kalle T Rytkönen et al.

    Reprod Sci. 2024 Oct;31(10):3159-3174. doi: 10.1007/s43032-024-01653-1. Epub 2024 Aug 1.

    Published on August 1, 2024

    Human reproductive success relies on the proper differentiation of the uterine endometrium to facilitate implantation, formation of the placenta, and pregnancy. This process involves two Read more

    PUBLICATION

    Synaptic proteome perturbations after maternal immune activation: Identification of embryonic and adult hippocampal changes 

    Anna Y Yotova et al.

    Brain Behav Immun. 2024 Oct;121:351-364. doi: 10.1016/j.bbi.2024.07.040. Epub 2024 Jul 31.

    Published on August 1, 2024

    CONCLUSIONS: Our data emphasise the dynamic effects of viral-like MIA on developing and mature hippocampi and provide novel targets for study following prenatal immune challenges. Read more