Publications

Publication
Tim Van Den Bossche et al. Proteomics. 2025 Jan 31:e202400321. doi: 10.1002/pmic.202400321. Online ahead of print. Published January 31, 2025
Metaproteomics enables the large-scale characterization of microbial community proteins, offering crucial insights into their taxonomic composition, functional activities, and interactions within their environments. By directly... Read more
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Sami Pietilä et al. Comput Biol Med. 2025 Mar;186:109743. doi: 10.1016/j.compbiomed.2025.109743. Epub 2025 Jan 26. Published January 27, 2025
With advances in sequencing technologies, the use of high-throughput sequencing to characterize microbial communities is becoming increasingly feasible. However, metagenomic assembly poses computational challenges in... Read more
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Li Wang et al. Bioact Mater. 2025 Jan 7;46:494-502. doi: 10.1016/j.bioactmat.2025.01.002. eCollection 2025 Apr. Published January 27, 2025
Hydrogel-based patches have demonstrated their values in diabetic wounds repair, particularly those intelligent dressings with continuous repair promoting and monitoring capabilities. Here, we propose a... Read more
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Xiang Lin et al. Bioact Mater. 2025 Jan 3;46:448-456. doi: 10.1016/j.bioactmat.2024.12.024. eCollection 2025 Apr. Published January 24, 2025
Long-term exposure to ultraviolet radiation compromises skin structural integrity and results in disruption of normal physiological functions. Stem cells have gained attention in anti-photoaging, while... Read more
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Henna Lehtonen et al. Cell Rep. 2025 Feb 25;44(2):115227. doi: 10.1016/j.celrep.2024.115227. Epub 2025 Jan 21. Published January 22, 2025
The pituitary gland is the central endocrine regulatory organ producing and releasing hormones that coordinate major body functions. The physical location of the pituitary gland... Read more
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Wali Inam et al. Adv Colloid Interface Sci. 2025 Apr;338:103400. doi: 10.1016/j.cis.2025.103400. Epub 2025 Jan 12. Published January 17, 2025
In the realm of hybrid nanomaterials, the construction of core/shell nanoparticles offer an effective strategy for encompassing a particle by a polymeric or other suitable... Read more
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Jani J Sormunen et al. Zoonoses Public Health. 2025 May;72(3):313-323. doi: 10.1111/zph.13208. Epub 2025 Jan 16. Published January 17, 2025
CONCLUSIONS: Ticks and TBPs are commonplace in urban green spaces in Finland. Enzootic cycles for Borrelia and Rickettsia appear to be well maintained within cities,... Read more
Publication
Prince Dadson et al. Am J Physiol Endocrinol Metab. 2025 Mar 1;328(3):E311-E324. doi: 10.1152/ajpendo.00220.2024. Epub 2025 Jan 17. Published January 17, 2025
In this study, we investigated the impact of bariatric surgery on the adipose proteome to better understand the metabolic and cellular mechanisms underlying weight loss... Read more
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Bruno M Saraiva et al. Nat Methods. 2025 Feb;22(2):283-286. doi: 10.1038/s41592-024-02562-6. Epub 2025 Jan 2. Published January 2, 2025
The expanding scale and complexity of microscopy image datasets require accelerated analytical workflows. NanoPyx meets this need through an adaptive framework enhanced for high-speed analysis.... Read more
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J Cell Sci. 2024 Feb 1;137(3):jcs261545. doi: 10.1242/jcs.261545. Epub 2024 Feb 7. Fluorescence microscopy is essential for studying living cells, tissues and organisms. However, the fluorescent light that switches on fluorescent molecules also harms the samples, jeopardizing the validity of results - particularly in techniques such as super-resolution microscopy, which demands extended illumination. Artificial intelligence (AI)-enabled software capable of denoising, image restoration, temporal interpolation or cross-modal style transfer has great potential to rescue live imaging data and limit photodamage. Yet we believe the focus should be on maintaining light-induced damage at levels that preserve natural cell behaviour. In this Opinion piece, we argue that a shift in role for AIs is needed - AI should be used to extract rich insights from gentle imaging rather than recover compromised data from harsh illumination. Although AI can enhance imaging, our ultimate goal should be to uncover biological truths, not just retrieve data. It is essential to prioritize minimizing photodamage over merely pushing technical limits. Our approach is aimed towards gentle acquisition and observation of undisturbed living systems, aligning with the essence of live-cell fluorescence microscopy. Published December 27, 2024
Fluorescence microscopy is essential for studying living cells, tissues and organisms. However, the fluorescent light that switches on fluorescent molecules also harms the samples, jeopardizing... Read more
Publication
Emily N Arner et al. Sci Signal. 2024 Dec 17;17(867):eado6057. doi: 10.1126/scisignal.ado6057. Epub 2024 Dec 17. Published December 17, 2024
The receptor tyrosine kinase AXL promotes tumor progression, metastasis, and therapy resistance through the induction of epithelial-mesenchymal transition (EMT). Here, we found that activation of... Read more
Publication
Adv Mater. 2024 May;36(19):e2310318. doi: 10.1002/adma.202310318. Epub 2024 Feb 20. Neutrophils are the most abundant white blood cells in the circulation and act as the first line of defense against infections. Increasing evidence suggests that neutrophils possess heterogeneous phenotypes and functional plasticity in human health and diseases, including cancer. Neutrophils play multifaceted roles in cancer development and progression, and an N1/N2 paradigm of neutrophils in cancer is proposed, where N1 neutrophils exert anti-tumor properties while N2 neutrophils display tumor-supportive and immune-suppressive functions. Selective activation of beneficial neutrophil population and targeted inhibition or re-polarization of tumor-promoting neutrophils has shown an important potential in tumor therapy. In addition, due to the natural inflammation-responsive and physical barrier-crossing abilities, neutrophils and their derivatives (membranes and extracellular vesicles (EVs)) are regarded as advanced drug delivery carriers for enhanced tumor targeting and improved therapeutic efficacy. In this review, the recent advances in engineering neutrophils for drug delivery and targeting neutrophils for remodeling tumor microenvironment (TME) are comprehensively presented. This review will provide a broad understanding of the potential of neutrophils in cancer therapy. Published December 10, 2024
Neutrophils are the most abundant white blood cells in the circulation and act as the first line of defense against infections. Increasing evidence suggests that... Read more
Last updated on June 25, 2025