Nataliia Petruk et al.Sci Rep. 2025 Mar 19;15(1):9449. doi: 10.1038/s41598-025-92841-9.Published March 20, 2025
CONCLUSIONS: High CD73 expression is associated with development of bone metastases. Zoledronate counteracts this effect. These results suggest that CD73 expression might serve as a... Read more
Joanna W Pylvänäinen et al.J Cell Sci. 2025 Mar 1;138(5):jcs263711. doi: 10.1242/jcs.263711. Epub 2025 Mar 17.Published March 17, 2025
Developing user-friendly image analysis software is essential for advancing biological and life science research. However, the interdisciplinary gap between software developers and life scientists presents... Read more
Santosh Lamichhane et al.medRxiv [Preprint]. 2025 Feb 24:2025.02.18.25322275. doi: 10.1101/2025.02.18.25322275.Published March 10, 2025
Recent studies reveal that gut microbes produce diverse bile acid conjugates, termed microbially conjugated bile acids (MCBAs). However, their regulation and health effects remain unclear.... Read more
Lu Fan et al.Smart Med. 2025 Feb 26;4(1):e137. doi: 10.1002/smmd.137. eCollection 2025 Mar.Published March 10, 2025
Wound healing has been a continuous critical focus in clinical practice, posing the ongoing challenges and burdens to patients. Current attempts tend to develop multi-drug... Read more
Jun-Nian Zhou et al.Smart Med. 2025 Feb 26;4(1):e134. doi: 10.1002/smmd.134. eCollection 2025 Mar.Published March 10, 2025
Mitochondria are crucial to cellular physiology, and growing evidence highlights the significant impact of mitochondrial dysfunction in diabetes, aging, neurodegenerative disorders, and cancers. Therefore, mitochondrial... Read more
Mahmoud Bazina et al.Acta Oncol. 2025 Mar 4;64:339-348. doi: 10.2340/1651-226X.2025.42202.Published March 4, 2025
BACKGROUND AND PURPOSE: Knowledge regarding the risk factors for early death in patients with head and neck squamous cell carcinoma (HNSCC) is scarce. This study... Read more
Beston Hamasur et al.Res Sq [Preprint]. 2025 Feb 18:rs.3.rs-5386988. doi: 10.21203/rs.3.rs-5386988/v2.Published March 4, 2025
CONCLUSIONS: BP-LAM has higher sensitivity than LF-LAM, including in HIV-negative people, potentially permitting the expansion of urine LAM testing beyond people with advanced immunosuppression. Read more
Robert Moulder et al.Diabetologia. 2025 Jun;68(6):1108-1114. doi: 10.1007/s00125-025-06394-7. Epub 2025 Feb 28.Published February 28, 2025
CONCLUSIONS/INTERPRETATION: The validated results reflect the landscape of biological changes accompanying type 1 diabetes. For example, the association of the targeted apolipoproteins with fasting C-peptide/glucose... Read more
Linda Nissi et al.Acta Otolaryngol. 2025 Apr;145(4):340-347. doi: 10.1080/00016489.2025.2461653. Epub 2025 Feb 10.Published February 10, 2025
CONCLUSIONS AND SIGNIFICANCE: Both p16 IHC and HPV-DNA ISH perform well as separate prognostic biomarkers for OS, DSS, and DFS on a population level. However,... Read more
Svetlana Yu Kovtareva et al.Eur J Pharm Biopharm. 2025 Mar;208:114654. doi: 10.1016/j.ejpb.2025.114654. Epub 2025 Feb 3.Published February 5, 2025
Mesoporous silica nanoparticles play an important role in drug delivery due to their high surface area, porous structure, tunable pore size, chemical stability and functionalization... Read more
Alejandro J Da Silva et al.iScience. 2025 Jan 4;28(2):111745. doi: 10.1016/j.isci.2025.111745. eCollection 2025 Feb 21.Published February 3, 2025
Talin-1 (TLN1) is best known to activate integrin receptors and transmit mechanical stimuli to the actin cytoskeleton at focal adhesions. However, the localization of TLN1... Read more
Victor Castro-Alves et al.J Chromatogr A. 2025 Mar 15;1744:465728. doi: 10.1016/j.chroma.2025.465728. Epub 2025 Jan 25.Published February 2, 2025
Mass spectrometry-based methods have become fundamental to exposome research, providing the capability to explore a broad spectrum of chemical exposures. Liquid and gas chromatography coupled... Read more
