Johanna Lilja et al.Nat Commun. 2024 Sep 12;15(1):8002. doi: 10.1038/s41467-024-52326-1.Published September 12, 2024
The KRAS oncogene drives many common and highly fatal malignancies. These include pancreatic, lung, and colorectal cancer, where various activating KRAS mutations have made the... Read more
Barbara Gawronska-Kozak et al.BMC Biol. 2024 Sep 11;22(1):193. doi: 10.1186/s12915-024-01990-2.Published September 10, 2024
CONCLUSIONS: The present data highlight the effect of hypoxia and Foxn1 on the protein profile and functionality of regenerative Foxn1^(-/-) DFs and demonstrate that the... Read more
Ilias Thomas et al.iScience. 2024 Aug 3;27(9):110654. doi: 10.1016/j.isci.2024.110654. eCollection 2024 Sep 20.Published September 10, 2024
Acute traumatic brain injury (TBI) is associated with substantial abnormalities in lipid biology, including changes in the structural lipids that are present in the myelin... Read more
Hanna Heikelä et al.FASEB J. 2024 Sep 15;38(17):e70034. doi: 10.1096/fj.202400333RR.Published September 9, 2024
The function of hydroxysteroid dehydrogenase 12 (HSD17B12) in lipid metabolism is poorly understood. To study this further, we created mice with hepatocyte-specific knockout of HSD17B12... Read more
Cristina Cocco et al.Neuropsychobiology. 2024;83(3-4):160-169. doi: 10.1159/000540673. Epub 2024 Sep 6.Published September 8, 2024
CONCLUSION: Our findings suggest that lower plasma levels of NAPP and AQEE are specifically associated with BD, thus possibly representing a diagnostic biomarker in mood... Read more
Leila S Coelho-Rato et al.J Cell Sci. 2024 Aug 15;137(16):jcs261386. doi: 10.1242/jcs.261386. Epub 2024 Aug 29.Published August 29, 2024
Intermediate filaments (IFs) comprise a large family of versatile cytoskeletal proteins, divided into six subtypes with tissue-specific expression patterns. IFs have a wide repertoire of... Read more
Xiwen Geng et al.Smart Med. 2024 May 22;3(2):e20240004. doi: 10.1002/SMMD.20240004. eCollection 2024 Jun.Published August 27, 2024
The development of non-antibiotic pharmaceuticals with biocompatible and efficient antibacterial properties is of great significance for the treatment of bacterial keratitis. In this study, we... Read more
Kexin Yi et al.Smart Med. 2023 Nov 13;2(4):e20230031. doi: 10.1002/SMMD.20230031. eCollection 2023 Nov.Published August 27, 2024
Circulating tumor DNA (ctDNA) is naked DNA molecules shed from the tumor cells into the peripheral blood circulation. They contain tumor-specific gene mutations and other... Read more
Ahmed Sabt et al.PLoS One. 2024 Aug 14;19(8):e0306124. doi: 10.1371/journal.pone.0306124. eCollection 2024.Published August 14, 2024
Multidrug resistance (MDR) mechanisms in cancer cells are greatly influenced by glutathione transferase P1-1 (hGSTP1-1). The use of synthetic or natural compounds as hGSTP1-1 inhibitors... Read more
Estibaliz Gómez-de-Mariscal et al.PLoS Biol. 2024 Aug 8;22(8):e3002740. doi: 10.1371/journal.pbio.3002740. eCollection 2024 Aug.Published August 8, 2024
In life sciences, tracking objects from movies enables researchers to quantify the behavior of single particles, organelles, bacteria, cells, and even whole animals. While numerous... Read more
Chang Liu et al.Research (Wash D C). 2024 Aug 6;7:0448. doi: 10.34133/research.0448. eCollection 2024.Published August 7, 2024
Nanomaterial-based drug delivery systems are susceptible to premature drug leakage and systemic toxicity due to lack of specific targeting, and live-cell drug delivery is also... Read more
Last updated on June 25, 2025
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