Varpu Rinne et al.Microbes Infect. 2025 Feb;27(2):105424. doi: 10.1016/j.micinf.2024.105424. Epub 2024 Sep 19.Published September 21, 2024
Lyme borreliosis is a disease caused by Borrelia burgdorferi sensu lato bacteria. Borrelia burgdorferi is known to induce prolonged extrafollicular immune responses and abnormal germinal... Read more
Alejandro J Da Silva et al.FEBS J. 2024 Nov;291(21):4830-4848. doi: 10.1111/febs.17271. Epub 2024 Sep 16.Published September 17, 2024
Heat shock factor 2 (HSF2) is a versatile transcription factor that regulates gene expression under stress conditions, during development, and in disease. Despite recent advances... Read more
Anna-Mari Haapanen-Saaristo et al.Biochem Biophys Res Commun. 2024 Nov 12;733:150682. doi: 10.1016/j.bbrc.2024.150682. Epub 2024 Sep 10.Published September 14, 2024
Global warming increases the risk of dangerous heat waves, which may have deleterious effects on humans and wildlife. Here, we have utilized zebrafish embryos as... Read more
Johanna Lilja et al.Nat Commun. 2024 Sep 12;15(1):8002. doi: 10.1038/s41467-024-52326-1.Published September 12, 2024
The KRAS oncogene drives many common and highly fatal malignancies. These include pancreatic, lung, and colorectal cancer, where various activating KRAS mutations have made the... Read more
Roosa Kattelus et al.Cell Mol Life Sci. 2024 Sep 12;81(1):399. doi: 10.1007/s00018-024-05429-3.Published September 12, 2024
Regulatory T cells (Tregs) play a key role in suppressing systemic effector immune responses, thereby preventing autoimmune diseases but also potentially contributing to tumor progression.... Read more
Robert Moulder et al.Front Mol Biosci. 2024 Aug 28;11:1446822. doi: 10.3389/fmolb.2024.1446822. eCollection 2024.Published September 12, 2024
INTRODUCTION: Organoid models enable three-dimensional representation of cellular systems, providing flexible and accessible research tools, and can highlight key biomolecules. Such models of the intestinal... Read more
Barbara Gawronska-Kozak et al.BMC Biol. 2024 Sep 11;22(1):193. doi: 10.1186/s12915-024-01990-2.Published September 10, 2024
CONCLUSIONS: The present data highlight the effect of hypoxia and Foxn1 on the protein profile and functionality of regenerative Foxn1^(-/-) DFs and demonstrate that the... Read more
Ilias Thomas et al.iScience. 2024 Aug 3;27(9):110654. doi: 10.1016/j.isci.2024.110654. eCollection 2024 Sep 20.Published September 10, 2024
Acute traumatic brain injury (TBI) is associated with substantial abnormalities in lipid biology, including changes in the structural lipids that are present in the myelin... Read more
Hanna Heikelä et al.FASEB J. 2024 Sep 15;38(17):e70034. doi: 10.1096/fj.202400333RR.Published September 9, 2024
The function of hydroxysteroid dehydrogenase 12 (HSD17B12) in lipid metabolism is poorly understood. To study this further, we created mice with hepatocyte-specific knockout of HSD17B12... Read more
Cristina Cocco et al.Neuropsychobiology. 2024;83(3-4):160-169. doi: 10.1159/000540673. Epub 2024 Sep 6.Published September 8, 2024
CONCLUSION: Our findings suggest that lower plasma levels of NAPP and AQEE are specifically associated with BD, thus possibly representing a diagnostic biomarker in mood... Read more
Leila S Coelho-Rato et al.J Cell Sci. 2024 Aug 15;137(16):jcs261386. doi: 10.1242/jcs.261386. Epub 2024 Aug 29.Published August 29, 2024
Intermediate filaments (IFs) comprise a large family of versatile cytoskeletal proteins, divided into six subtypes with tissue-specific expression patterns. IFs have a wide repertoire of... Read more
