Candy Laura Steffen et al.Commun Biol. 2024 Jul 9;7(1):837. doi: 10.1038/s42003-024-06523-9.Published July 9, 2024
Hyperactive Ras signalling is found in most cancers. Ras proteins are only active in membrane nanoclusters, which are therefore potential drug targets. We previously showed... Read more
Madhukar Vedantham et al.FASEB J. 2024 Jul 15;38(13):e23775. doi: 10.1096/fj.202400484R.Published July 5, 2024
Inflammatory bowel disease (IBD) is a chronic disease of the gastrointestinal tract affecting millions of people. Here, we investigated the expression and functions of poly(ADP-ribose)... Read more
Jose Juan Almagro Armenteros et al.Diabetes Metab Res Rev. 2024 Jul;40(5):e3833. doi: 10.1002/dmrr.3833.Published July 4, 2024
CONCLUSIONS: Features that differ between individuals with slow and rapid decline in β-cell mass could be valuable in staging and prediction of the rate of... Read more
Jens C Luoto et al.J Extracell Biol. 2023 Nov 27;2(12):e124. doi: 10.1002/jex2.124. eCollection 2023 Dec.Published June 28, 2024
Extracellular vesicles (EVs) are important mediators of intercellular communication involved in local and long-range signalling of cancer metastasis. The onset of invasion is the key... Read more
Lonnie P Swift et al.Nat Commun. 2024 Jun 25;15(1):5392. doi: 10.1038/s41467-024-49583-5.Published June 25, 2024
DNA double-strand breaks (DSBs), such as those produced by radiation and radiomimetics, are amongst the most toxic forms of cellular damage, in part because they... Read more
Yusuke Nakako et al.Pathol Res Pract. 2024 Aug;260:155420. doi: 10.1016/j.prp.2024.155420. Epub 2024 Jun 20.Published June 22, 2024
Odontogenic tumors (OGTs), which originate from cells of odontogenic apparatus and their remnants, are rare entities. Primary intraosseous carcinoma NOS (PIOC), is one of the... Read more
Majid Momeny et al.EMBO Mol Med. 2024 Jul;16(7):1603-1629. doi: 10.1038/s44321-024-00088-0. Epub 2024 Jun 17.Published June 17, 2024
Despite clinical benefits of tyrosine kinase inhibitors (TKIs) in cancer, most tumors can reactivate proliferation under TKI therapy. Here we present transcriptional profiling of HER2+... Read more
Santosh D Bhosale et al.iScience. 2024 May 22;27(6):110048. doi: 10.1016/j.isci.2024.110048. eCollection 2024 Jun 21.Published June 17, 2024
In-utero and dietary factors make important contributions toward health and development in early childhood. In this respect, serum proteomics of maturing infants can provide insights... Read more
Jenni Viitaharju et al.Proteomics. 2024 Jul;24(14):e2300340. doi: 10.1002/pmic.202300340. Epub 2024 Jun 14.Published June 14, 2024
The breast milk composition includes a multitude of bioactive factors such as viable cells, lipids and proteins. Measuring the levels of specific proteins in breast... Read more
Samira Salihovic et al.Nat Commun. 2024 Jun 3;15(1):4567. doi: 10.1038/s41467-024-48763-7.Published June 3, 2024
Improved biomarkers are needed for pediatric inflammatory bowel disease. Here we identify a diagnostic lipidomic signature for pediatric inflammatory bowel disease by analyzing blood samples... Read more
Marika K A Koivu et al.Oncogene. 2024 Jul;43(29):2253-2265. doi: 10.1038/s41388-024-03070-9. Epub 2024 May 28.Published May 28, 2024
Genetic changes in the ERBB family of receptor tyrosine kinases serve as oncogenic driver events and predictive biomarkers for ERBB inhibitor drugs. ERBB3 is a... Read more
