Publications

Publication

Indignity of Nazi data: reflections on the utilization of illicit research

Iman Farahani et al. Med Health Care Philos. 2024 Sep;27(3):381-387. doi: 10.1007/s11019-024-10212-z. Epub 2024 Jun 6. Published June 6, 2024

Human rights may feel self-apparent to us, but less than 80 years ago, one of the most advanced countries at the time acted based on... Read more

Publication

Identification and validation of a blood- based diagnostic lipidomic signature of pediatric inflammatory bowel disease

Samira Salihovic et al. Nat Commun. 2024 Jun 3;15(1):4567. doi: 10.1038/s41467-024-48763-7. Published June 3, 2024

Improved biomarkers are needed for pediatric inflammatory bowel disease. Here we identify a diagnostic lipidomic signature for pediatric inflammatory bowel disease by analyzing blood samples... Read more

Publication

Trans-activating mutations of the pseudokinase ERBB3

Marika K A Koivu et al. Oncogene. 2024 Jul;43(29):2253-2265. doi: 10.1038/s41388-024-03070-9. Epub 2024 May 28. Published May 28, 2024

Genetic changes in the ERBB family of receptor tyrosine kinases serve as oncogenic driver events and predictive biomarkers for ERBB inhibitor drugs. ERBB3 is a... Read more

Publication

Long noncoding RNA LIRIL2R modulates FOXP3 levels and suppressive function of human CD4+ regulatory T cells by regulating IL2RA

Syed Bilal Ahmad Andrabi et al. Proc Natl Acad Sci U S A. 2024 Jun 4;121(23):e2315363121. doi: 10.1073/pnas.2315363121. Epub 2024 May 28. Published May 28, 2024

Regulatory T cells (Tregs) are central in controlling immune responses, and dysregulation of their function can lead to autoimmune disorders or cancer. Despite extensive studies... Read more

Publication

A proximal enhancer regulates RORA expression during early human Th17 cell differentiation

Ubaid Ullah Kalim et al. Clin Immunol. 2024 Jul;264:110261. doi: 10.1016/j.clim.2024.110261. Epub 2024 May 22. Published May 24, 2024

Gene regulatory elements, such as enhancers, greatly influence cell identity by tuning the transcriptional activity of specific cell types. Dynamics of enhancer landscape during early... Read more

Publication

Comparative Metabolomics and Microbiome Analysis of Ethanol versus OMNImet/gene•GUT Fecal Stabilization

Heidi Isokääntä et al. Anal Chem. 2024 Jun 4;96(22):8893-8904. doi: 10.1021/acs.analchem.3c04436. Epub 2024 May 23. Published May 23, 2024

Metabolites from feces provide important insights into the functionality of the gut microbiome. As immediate freezing is not always feasible in gut microbiome studies, there... Read more

Publication

Serum hydroxysteroid (17beta) dehydrogenase 1 concentration in pregnant women correlates with pregnancy-associated plasma protein A but does not serve as an independent marker for preeclampsia†

Taija Heinosalo et al. Biol Reprod. 2024 Aug 15;111(2):436-447. doi: 10.1093/biolre/ioae078. Published May 23, 2024

Hydroxysteroid (17beta) dehydrogenase 1 (HSD17B1) is a steroid synthetic enzyme expressed in ovarian granulosa cells and placental syncytiotrophoblasts. Here, HSD17B1 serum concentration was measured with... Read more