Turku Bioscience Centre

Turku Bioscience Centre is an advanced core facility and research centre hosted jointly by University of Turku and Åbo Akademi University.

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News

Professor Riitta Lahesmaa has been elected as a member of EMBO

July 1, 2025

The European Molecular Biology Organization (EMBO) has selected Professor Riitta Lahesmaa from the University of Turku as its member. The organization annually elects new members based on scientific merit. EMBO is an international organization that Read more

Research Council of Finland Awards Funding to Turku Bioscience Researchers

June 24, 2025

New Research Council of Finland funding was granted to Turku Bioscience researchers: Riitta Lahesmaa (Turku Bioscience Centre, InFlames Flagship): New regulators of the human immune response, €599,985 Affiliated group leader:Pieta Mattila (Department of Biomedicine, InFlames Read more

funding news Research Council of Finland suomen akatemia

Guillaume Jacquemet appointed to K. Albin Johansson Research Professorship

June 19, 2025

Associate Professor, InFLAMES PI Guillaume Jacquemet (Åbo Akademi University) and our affiliated Group Leader has been appointed to a prestigious five-year K. Albin Johansson Research Professorship funded by the K. Albin Johansson Foundation and the Read more

Meng Wang (Mona) Successfully Defended PhD on Novel Immune and Genetic Drivers of Melanoma

June 16, 2025

Meng Wang from our affiliated Figueiredo Lab (MIORG) successfully defended her PhD thesis “Novel Immune and Genetic Drivers of Melanoma: Integrative and New Preclinical Models to Uncover the Impact of New Chromosomal and Transcriptomic Changes Read more

cancer Melanoma

Researchers elucidate the role of jaundice during malaria as a metabolic response against Plasmodium infection

June 13, 2025

Researchers from the Turku Bioscience Centre at the University of Turku in Finland collaborated with a leading malaria research group at Gulbenkian Institute of Molecular Medicine (GIMM) in Portugal to elucidate a metabolite-based defense mechanism Read more

Karoliina Hirvonen Successfully Defended PhD on Serum Proteome and Enterovirus Research

May 23, 2025

Karoliina Hirvonen from Riitta Lahesmaa lab defended her PhD thesis “Proteomics Insights into Type 1 Diabetes Development – Investigating Changes in Serum Proteome and the Role of Persistent Enterovirus Infection” on Thursday the 22nd of May Read more

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Events

34th BioCity Symposium: Transforming drug development for tomorrow

August 28, 2025

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August 28, 2025 - August 29, 2025 @ 8:30 am - 5:00 pm - The 34th BioCity Symposium focuses on drug development across a range of Event details

Frontiers of Science: Prof. Hiroki Ueda

September 18, 2025

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18th September at 12:00 Onsite event in Presidentti auditorium, BioCity Autumn 2025 program Prof. Hiroki Ueda, University of Tokyo, Japan Why do we sleep? The role of calcium and phosphorylation in sleep Host: Diana Lehotina Event details

Frontiers of Science: Prof. Olli Kallioniemi

October 2, 2025

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2nd October at 12:00 Onsite event in Presidentti auditorium, BioCity Autumn 2025 program Prof. Olli Kallioniemi, FIMM, HiLife, University of Helsinki, Finland Technology-, data- and AI-driven translational cancer research Host: Klaus Elenius (klaele@utu.fi) Coffee and Event details

Frontiers of Science: Prof. Pere Roca-Cusachs

October 9, 2025

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9th October at 12:00 Onsite event in Presidentti auditorium, BioCity Autumn 2025 program Prof. Pere Roca-Cusachs, University of Barcelona, Spain Understanding and controlling mechanotransduction, from integrins to the nucleus Host: Johanna Ivaska (johanna.ivaska@utu.fi) Coffee and Event details

BioCity Turku Guest Seminar: Prof. Mark Daly

October 21, 2025

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21st October at 12:00-13:00 Onsite event in Presidentti auditorium, BioCity Prof. Mark Daly, Massachusetts General Hospital; Harvard Medical School, USA Title TBA Host: Teemu Niiranen (tejuni@uti.fi) Mark Daly is the founding Chief of the Event details

Turku Imaging Day 2025

October 22, 2025

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22nd October, whole-day event Onsite event in Holiday Club Caribia, Turku Save the date from your agenda, and stay tuned for updates. This year the event is arranged in Holiday Club Caribia. Meanwhile, if you Event details

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Recent Publications

Sketching T cell atlases in the single-cell era: challenges and recommendations

Itana Bojović et al.

Immunol Cell Biol. 2025 Jun 29. doi: 10.1111/imcb.70040. Online ahead of print.

Published on June 29, 2025

Recent advances in single-cell technologies have enabled the creation of comprehensive cell atlases, reference maps of various cell types within organisms. Here we specifically focus Read more

In situ construction of ossification micro-units for critical bone regeneration via sustained lifting of epigenetic suppression

Wu Yang et al.

J Control Release. 2025 Jun 23:113978. doi: 10.1016/j.jconrel.2025.113978. Online ahead of print.

Published on June 25, 2025

Critical-sized bone defects present significant clinical challenges due to insufficient stem cell recruitment, epigenetic suppression of osteogenesis, and inadequate mineralization. Among the epigenetic suppression mechanisms, Read more

Cytoskeletal crosstalk in macrophages: Vimentin drives ECM remodeling in tumor invasion and tissue plasticity

John E Eriksson et al.

Dev Cell. 2025 Jun 23;60(12):1655-1657. doi: 10.1016/j.devcel.2025.05.015.

Published on June 24, 2025

In this issue of Developmental Cell, Huang et al. assess the role of vimentin intermediate filaments during extracellular matrix (ECM) degradation by macrophages. Vimentin stabilizes Read more

Integrin β1 activity controls colony morphology during human pluripotent stem cell state transitions

Maria E Taskinen et al.

Stem Cell Reports. 2025 Jun 17:102538. doi: 10.1016/j.stemcr.2025.102538. Online ahead of print.

Published on June 20, 2025

Integrin β1-mediated adhesion is dispensable in early mouse embryogenesis (pre-implantation) but indispensable post-implantation, suggesting distinct roles for β1-integrin-mediated adhesions in the naive (pre-implantation) versus primed Read more

The Next Frontier: Unveiling Novel Approaches for Combating Multidrug-Resistant Bacteria

Praveen Mallari et al.

Pharm Res. 2025 Jun 16. doi: 10.1007/s11095-025-03871-x. Online ahead of print.

Published on June 16, 2025

CONCLUSION: Despite the substantial obstacles to getting bench findings to the patient, numerous scientists are still working towards this goal. Both the application of antibiotic Read more

A metabolite-based resistance mechanism against malaria

Ana Figueiredo et al.

Science. 2025 Jun 12;388(6752):eadq6741. doi: 10.1126/science.adq6741. Epub 2025 Jun 12.

Published on June 12, 2025

Jaundice is a common presentation of Plasmodium falciparum malaria, which arises from the accumulation of circulating bilirubin. It is not understood whether it represents an Read more

NRF2-mediated persistent adaptation of oesophageal adenocarcinoma cells to HER2 inhibition

Wei Zhang et al.

Oncogene. 2025 Jun 5. doi: 10.1038/s41388-025-03459-0. Online ahead of print.

Published on June 5, 2025

The human epidermal growth factor receptor 2 (HER2, also known as ERBB2) is a commonly over-expressed oncoprotein in oesophageal adenocarcinoma (OAC). Nonetheless, HER2-blocking agents have Read more

Biochemical and structural characterization of chlorite dismutase enzyme from Pseudomonas aeruginosa

Dimitrios V Nokas et al.

FEBS J. 2025 Jun 3. doi: 10.1111/febs.70151. Online ahead of print.

Published on June 3, 2025

Industrialization and urbanization have caused serious contamination of water bodies, and the removal of chemical contaminants has become a major challenge. Chlorite is a harmful Read more

A guide to heat shock factors as multifunctional transcriptional regulators

Hendrik S E Hästbacka et al.

FEBS J. 2025 Jun 2. doi: 10.1111/febs.70139. Online ahead of print.

Published on June 2, 2025

The heat shock factors (HSFs) form a family of transcription factors, which are evolutionarily conserved in eukaryotes. They are best known as transcriptional regulators of Read more

Proliferation of Human Cervical Cancer Cells Responds to Surface Properties of Bicomponent Polymer Coatings

Emil Rosqvist et al.

Nanomaterials (Basel). 2025 May 9;15(10):716. doi: 10.3390/nano15100716.

Published on May 27, 2025

The proliferation of human cervical cancer (Hela) cells was investigated on a series of nanostructured polymer latex surfaces. The physico-chemical properties of the surfaces, composed Read more

Dynamic regulation of integrin β1 phosphorylation supports invasion of breast cancer cells

James R W Conway et al.

Nat Cell Biol. 2025 May 26. doi: 10.1038/s41556-025-01663-4. Online ahead of print.

Published on May 26, 2025

Integrins provide an essential bridge between cancer cells and the extracellular matrix, playing a central role in every stage of disease progression. Despite the recognized Read more

Mass spectrometric insights into the protein composition of human cutaneous neurofibromas: comparison of neurofibromas with the overlying skin

Roope A Kallionpää et al.

Br J Cancer. 2025 May 20. doi: 10.1038/s41416-025-03055-9. Online ahead of print.

Published on May 20, 2025

CONCLUSION: The cNFs are relatively quiescent, consistent with their benign nature and limited growth potential. The development of pharmacological therapy for cNFs requires overcoming the Read more

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