Frontiers of Science: The molecular chaperone Hsp90: probing its functions with drugs and gene deletion

    Prof. Didier Picard, University of Geneva, Switzerland
    online event at 12:00
    The molecular chaperone Hsp90: probing its functions with drugs and gene deletions

    host: Outi Salo-Ahen (outi.salo-ahen@abo.fi)

    Register latest April 7th 12:00
    https://link.webropolsurveys.com/S/D7C1FD56DD28A4A9

     

    Students and early-career postdocs are welcome to share a virtual cup of coffee and discuss with Prof. Picard after the seminar. This is a great possibility to learn hosting skills in friendly environment and create connections for future. Every student are welcome to join, in spite of which research group they belong to.

    If you got interested, after registering to the event please send an email to biocityturku@bioscience.fi

     

    Didier Picard is a professor and a research group leader in the department of cell biology in the University of Geneva, Switzerland. His research interests lies in signal integration at the cellular level and its implications in breast cancer, and particularly in understanding the molecular mechanisms of signal transduction by ER and its crosstalk with other intra- and extracellular signals. His group studies also the Hsp90 molecular chaperone machine where they are particularly interested in determining the in vivo functions of the Hsp90 molecular chaperone complex both in mammalian cells and in the mouse, using genetic, biochemical, proteomic and pharmacological tools.

     

    Seleced publications

    A Joshi, L Dai, Y Liu, J Lee, NM Ghahhari… D Picard (2020) The mitochondrial HSP90 paralog TRAP1 forms an OXPHOS-regulated tetramer and is involved in mitochondrial metabolic homeostasis. BMC Biol. 18, 10

    K Bhattacharya, L Weidenauer, TM Luengo… D Picard (2020) The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation. Nature Communications 11:5975

    Segala G, Bennesch MA, Ghahhari NM, Pandey DP, Echeverria PC, Karch F, Maeda RK, Picard D (2019) Vps11 and Vps18 of Vps-C membrane traffic complexes are E3 ubiquitin ligases and fine-tune signalling. Nature Communications 10:1833

     

    General information

    • All spring 2021 Frontiers of Science seminars are arranged online as eTALKs.
    • Registration is obligatory and links to register are in BioCity Turku website (https://biocityturku.fi/) and advertised in our news feed.
    • For Turku affiliated people it is now possible to register to all spring 2021 seminars in one go.
    • Registration closes and zoom link is sent to participants one day before the event.
    • If you are a student and later wish to get a certificate of attendance from the Frontier of Science seminars, please fill in your student number.
    • If you wish to follow BioCity Turku news feed and receive up to date information about the Frontiers of Science seminars and other events, please contact biocityturku@bioscience.fi

     

    Please note that any audio or video recording of the seminars is strictly forbidden.