Publications

PUBLICATION

ECCB2024: The 23rd European Conference on Computational Biology 

Anu Kukkonen-Macchi et al.

Bioinformatics. 2024 Sep 1;40(Suppl 2):ii1-ii3. doi: 10.1093/bioinformatics/btae422.

Published on September 4, 2024

No abstract

PUBLICATION

Intermediate filaments at a glance 

Leila S Coelho-Rato et al.

J Cell Sci. 2024 Aug 15;137(16):jcs261386. doi: 10.1242/jcs.261386. Epub 2024 Aug 29.

Published on August 29, 2024

Intermediate filaments (IFs) comprise a large family of versatile cytoskeletal proteins, divided into six subtypes with tissue-specific expression patterns. IFs have a wide repertoire of Read more

PUBLICATION

Iron-doped nanozymes with spontaneous peroxidase-mimic activity as a promising antibacterial therapy for bacterial keratitis 

Xiwen Geng et al.

Smart Med. 2024 May 22;3(2):e20240004. doi: 10.1002/SMMD.20240004. eCollection 2024 Jun.

Published on August 27, 2024

The development of non-antibiotic pharmaceuticals with biocompatible and efficient antibacterial properties is of great significance for the treatment of bacterial keratitis. In this study, we Read more

PUBLICATION

Emerging ctDNA detection strategies in clinical cancer theranostics 

Kexin Yi et al.

Smart Med. 2023 Nov 13;2(4):e20230031. doi: 10.1002/SMMD.20230031. eCollection 2023 Nov.

Published on August 27, 2024

Circulating tumor DNA (ctDNA) is naked DNA molecules shed from the tumor cells into the peripheral blood circulation. They contain tumor-specific gene mutations and other Read more

PUBLICATION

Novel coumarin-6-sulfonamide-chalcone hybrids as glutathione transferase P1-1 inhibitors 

Ahmed Sabt et al.

PLoS One. 2024 Aug 14;19(8):e0306124. doi: 10.1371/journal.pone.0306124. eCollection 2024.

Published on August 14, 2024

Multidrug resistance (MDR) mechanisms in cancer cells are greatly influenced by glutathione transferase P1-1 (hGSTP1-1). The use of synthetic or natural compounds as hGSTP1-1 inhibitors Read more

PUBLICATION

CellTracksColab is a platform that enables compilation, analysis, and exploration of cell tracking data 

Estibaliz Gómez-de-Mariscal et al.

PLoS Biol. 2024 Aug 8;22(8):e3002740. doi: 10.1371/journal.pbio.3002740. eCollection 2024 Aug.

Published on August 8, 2024

In life sciences, tracking objects from movies enables researchers to quantify the behavior of single particles, organelles, bacteria, cells, and even whole animals. While numerous Read more

PUBLICATION

Utilizing Macrophages Missile for Sulfate-Based Nanomedicine Delivery in Lung Cancer Therapy 

Chang Liu et al.

Research (Wash D C). 2024 Aug 6;7:0448. doi: 10.34133/research.0448. eCollection 2024.

Published on August 7, 2024

Nanomaterial-based drug delivery systems are susceptible to premature drug leakage and systemic toxicity due to lack of specific targeting, and live-cell drug delivery is also Read more

PUBLICATION

Synaptic proteome perturbations after maternal immune activation: Identification of embryonic and adult hippocampal changes 

Anna Y Yotova et al.

Brain Behav Immun. 2024 Oct;121:351-364. doi: 10.1016/j.bbi.2024.07.040. Epub 2024 Jul 31.

Published on August 1, 2024

CONCLUSIONS: Our data emphasise the dynamic effects of viral-like MIA on developing and mature hippocampi and provide novel targets for study following prenatal immune challenges. Read more

PUBLICATION

Gene Regulatory Network Analysis of Decidual Stromal Cells and Natural Killer Cells 

Kalle T Rytkönen et al.

Reprod Sci. 2024 Oct;31(10):3159-3174. doi: 10.1007/s43032-024-01653-1. Epub 2024 Aug 1.

Published on August 1, 2024

Human reproductive success relies on the proper differentiation of the uterine endometrium to facilitate implantation, formation of the placenta, and pregnancy. This process involves two Read more

PUBLICATION

Inferring Tree-Shaped Single-Cell Trajectories with Totem 

António G G Sousa et al.

Methods Mol Biol. 2024;2812:169-191. doi: 10.1007/978-1-0716-3886-6_9.

Published on July 27, 2024

Single-cell transcriptomics allows unbiased characterization of cell heterogeneity in a sample by profiling gene expression at single-cell level. These profiles capture snapshots of transient or Read more

PUBLICATION

HSV-1 and Cellular miRNAs in CSF-Derived Exosomes as Diagnostically Relevant Biomarkers for Neuroinflammation 

Christian Scheiber et al.

Cells. 2024 Jul 17;13(14):1208. doi: 10.3390/cells13141208.

Published on July 26, 2024

Virus-associated chronic inflammation may contribute to autoimmunity in a number of diseases. In the brain, autoimmune encephalitis appears related to fluctuating reactivation states of neurotropic Read more

PUBLICATION

The PP2A regulator IER5L supports prostate cancer progression 

Jana R Crespo et al.

Cell Death Dis. 2024 Jul 18;15(7):514. doi: 10.1038/s41419-024-06907-z.

Published on July 18, 2024

Prostate cancer exhibits high prevalence and accounts for a high number of cancer-related deaths. The discovery and characterization of molecular determinants of aggressive prostate cancer Read more