Hendrik S E Hästbacka et al.FEBS J. 2025 Jun 2. doi: 10.1111/febs.70139. Online ahead of print.Published June 2, 2025
The heat shock factors (HSFs) form a family of transcription factors, which are evolutionarily conserved in eukaryotes. They are best known as transcriptional regulators of... Read more
Emil Rosqvist et al.Nanomaterials (Basel). 2025 May 9;15(10):716. doi: 10.3390/nano15100716.Published May 27, 2025
The proliferation of human cervical cancer (Hela) cells was investigated on a series of nanostructured polymer latex surfaces. The physico-chemical properties of the surfaces, composed... Read more
James R W Conway et al.Nat Cell Biol. 2025 May 26. doi: 10.1038/s41556-025-01663-4. Online ahead of print.Published May 26, 2025
Integrins provide an essential bridge between cancer cells and the extracellular matrix, playing a central role in every stage of disease progression. Despite the recognized... Read more
Roope A Kallionpää et al.Br J Cancer. 2025 May 20. doi: 10.1038/s41416-025-03055-9. Online ahead of print.Published May 20, 2025
CONCLUSION: The cNFs are relatively quiescent, consistent with their benign nature and limited growth potential. The development of pharmacological therapy for cNFs requires overcoming the... Read more
Anna-Mari Haapanen-Saaristo et al.Micron. 2025 May 9;196-197:103847. doi: 10.1016/j.micron.2025.103847. Online ahead of print.Published May 14, 2025
Tardigrades are well-known for their ability to tolerate extreme environmental conditions such as heat, drought and lack of oxygen by undergoing cryptobiosis. The molecular responses... Read more
Iivari Kleino et al.Bioinform Adv. 2025 Apr 4;5(1):vbaf069. doi: 10.1093/bioadv/vbaf069. eCollection 2025.Published May 7, 2025
MOTIVATION: The analysis of cell migration using time-lapse microscopy typically focuses on track characteristics for classification and statistical evaluation of migration behaviour. However, considerable heterogeneity... Read more
Minna Ampuja et al.HGG Adv. 2025 May 5;6(3):100446. doi: 10.1016/j.xhgg.2025.100446. Online ahead of print.Published May 7, 2025
Non-syndromic congenital heart defects (CHDs) are occasionally familial and left ventricular outflow tract obstruction (LVOTO) defects are among the subtypes with the highest hereditability. The... Read more
Kevin Daupin et al.Cell Stress Chaperones. 2025 May 1:100079. doi: 10.1016/j.cstres.2025.100079. Online ahead of print.Published May 3, 2025
Heat shock transcription factors 1 and 2 (HSF1 and HSF2) are the major regulators of the cellular response to stressors, notably to heat shock and... Read more
Maria K Jaakkola et al.Sci Rep. 2025 May 2;15(1):15393. doi: 10.1038/s41598-025-98492-0.Published May 2, 2025
Pathway analysis is a frequent step in studies involving gene or protein expression data, but most of the available pathway methods are designed for simple... Read more
Emil Hiitola et al.Sci Adv. 2025 May 2;11(18):eadt9846. doi: 10.1126/sciadv.adt9846. Epub 2025 Apr 30.Published April 30, 2025
Clonal hematopoiesis (CH) becomes more prevalent with aging and may influence inflammatory diseases by altering immune function. While CH of indeterminate potential (CHIP) promotes inflammation... Read more
Erica Routila et al.Cancer Med. 2025 May;14(9):e70717. doi: 10.1002/cam4.70717.Published April 27, 2025
CONCLUSIONS: We demonstrate that while integrin glycovariants are abundant in HNSCC tumors and ITGB1-WFL was associated with invasiveness, integrin glycovariants do not directly correlate with... Read more
Rayan Nikkilä et al.Head Neck Pathol. 2025 Apr 25;19(1):45. doi: 10.1007/s12105-025-01784-0.Published April 25, 2025
CONCLUSION: The GWAS detected two novel genetic associations with OTSCC. Further research is needed to identify the genes at these loci that contribute to the... Read more
Last updated on June 25, 2025
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