Publications

    Publication
    Sketching T cell atlases in the single-cell era: challenges and recommendations 
    Itana Bojović et al. Immunol Cell Biol. 2025 Jun 29. doi: 10.1111/imcb.70040. Online ahead of print. Published June 29, 2025
    Recent advances in single-cell technologies have enabled the creation of comprehensive cell atlases, reference maps of various cell types within organisms. Here we specifically focus... Read more
    Publication
    In situ construction of ossification micro-units for critical bone regeneration via sustained lifting of epigenetic suppression 
    Wu Yang et al. J Control Release. 2025 Jun 23:113978. doi: 10.1016/j.jconrel.2025.113978. Online ahead of print. Published June 25, 2025
    Critical-sized bone defects present significant clinical challenges due to insufficient stem cell recruitment, epigenetic suppression of osteogenesis, and inadequate mineralization. Among the epigenetic suppression mechanisms,... Read more
    Publication
    Cytoskeletal crosstalk in macrophages: Vimentin drives ECM remodeling in tumor invasion and tissue plasticity 
    John E Eriksson et al. Dev Cell. 2025 Jun 23;60(12):1655-1657. doi: 10.1016/j.devcel.2025.05.015. Published June 24, 2025
    In this issue of Developmental Cell, Huang et al. assess the role of vimentin intermediate filaments during extracellular matrix (ECM) degradation by macrophages. Vimentin stabilizes... Read more
    Publication
    Integrin β1 activity controls colony morphology during human pluripotent stem cell state transitions 
    Maria E Taskinen et al. Stem Cell Reports. 2025 Jun 17:102538. doi: 10.1016/j.stemcr.2025.102538. Online ahead of print. Published June 20, 2025
    Integrin β1-mediated adhesion is dispensable in early mouse embryogenesis (pre-implantation) but indispensable post-implantation, suggesting distinct roles for β1-integrin-mediated adhesions in the naive (pre-implantation) versus primed... Read more
    Publication
    The Next Frontier: Unveiling Novel Approaches for Combating Multidrug-Resistant Bacteria 
    Praveen Mallari et al. Pharm Res. 2025 Jun 16. doi: 10.1007/s11095-025-03871-x. Online ahead of print. Published June 16, 2025
    CONCLUSION: Despite the substantial obstacles to getting bench findings to the patient, numerous scientists are still working towards this goal. Both the application of antibiotic... Read more
    Publication
    A metabolite-based resistance mechanism against malaria 
    Ana Figueiredo et al. Science. 2025 Jun 12;388(6752):eadq6741. doi: 10.1126/science.adq6741. Epub 2025 Jun 12. Published June 12, 2025
    Jaundice is a common presentation of Plasmodium falciparum malaria, which arises from the accumulation of circulating bilirubin. It is not understood whether it represents an... Read more
    Publication
    NRF2-mediated persistent adaptation of oesophageal adenocarcinoma cells to HER2 inhibition 
    Wei Zhang et al. Oncogene. 2025 Jun 5. doi: 10.1038/s41388-025-03459-0. Online ahead of print. Published June 5, 2025
    The human epidermal growth factor receptor 2 (HER2, also known as ERBB2) is a commonly over-expressed oncoprotein in oesophageal adenocarcinoma (OAC). Nonetheless, HER2-blocking agents have... Read more
    Publication
    Biochemical and structural characterization of chlorite dismutase enzyme from Pseudomonas aeruginosa 
    Dimitrios V Nokas et al. FEBS J. 2025 Jun 3. doi: 10.1111/febs.70151. Online ahead of print. Published June 3, 2025
    Industrialization and urbanization have caused serious contamination of water bodies, and the removal of chemical contaminants has become a major challenge. Chlorite is a harmful... Read more
    Publication
    A guide to heat shock factors as multifunctional transcriptional regulators 
    Hendrik S E Hästbacka et al. FEBS J. 2025 Jun 2. doi: 10.1111/febs.70139. Online ahead of print. Published June 2, 2025
    The heat shock factors (HSFs) form a family of transcription factors, which are evolutionarily conserved in eukaryotes. They are best known as transcriptional regulators of... Read more
    Publication
    Proliferation of Human Cervical Cancer Cells Responds to Surface Properties of Bicomponent Polymer Coatings 
    Emil Rosqvist et al. Nanomaterials (Basel). 2025 May 9;15(10):716. doi: 10.3390/nano15100716. Published May 27, 2025
    The proliferation of human cervical cancer (Hela) cells was investigated on a series of nanostructured polymer latex surfaces. The physico-chemical properties of the surfaces, composed... Read more
    Publication
    Dynamic regulation of integrin β1 phosphorylation supports invasion of breast cancer cells 
    James R W Conway et al. Nat Cell Biol. 2025 May 26. doi: 10.1038/s41556-025-01663-4. Online ahead of print. Published May 26, 2025
    Integrins provide an essential bridge between cancer cells and the extracellular matrix, playing a central role in every stage of disease progression. Despite the recognized... Read more
    Publication
    Mass spectrometric insights into the protein composition of human cutaneous neurofibromas: comparison of neurofibromas with the overlying skin 
    Roope A Kallionpää et al. Br J Cancer. 2025 May 20. doi: 10.1038/s41416-025-03055-9. Online ahead of print. Published May 20, 2025
    CONCLUSION: The cNFs are relatively quiescent, consistent with their benign nature and limited growth potential. The development of pharmacological therapy for cNFs requires overcoming the... Read more
    Last updated on June 25, 2025