Ana Hernández de Sande et al.Genome Med. 2025 Oct 6;17(1):112. doi: 10.1186/s13073-025-01530-9.Published October 7, 2025
CONCLUSIONS: We demonstrate that miRNA gene transcriptional activity is widely impacted in immune cells by aging and during disease development and further identify the corresponding... Read more
Anni Kontouri et al.Phytochemistry. 2025 Sep 27;242:114692. doi: 10.1016/j.phytochem.2025.114692. Online ahead of print.Published September 29, 2025
Tau class glutathione transferases (GSTUs) play essential roles in plant defense by facilitating the nucleophilic attack of glutathione (GSH) to a wide range of electrophilic... Read more
Anna-Katariina Aatsinki et al.bioRxiv [Preprint]. 2025 Sep 16:2024.06.05.597641. doi: 10.1101/2024.06.05.597641.Published September 26, 2025
Transit time, fluid intake, diet, and overall gut health all influence stool consistency. However, the relationships between the gut microbiota, metabolome (microbial metabolites), and stool... Read more
Michael Santos Silva et al.J Proteomics. 2025 Sep 16;322:105536. doi: 10.1016/j.jprot.2025.105536. Online ahead of print.Published September 18, 2025
Human papillomavirus (HPV) is a major driver of cervical and other epithelial cancers, with the viral oncoprotein E6 playing a central role in tumorigenesis by... Read more
Jenny C Pessa et al.Sci Adv. 2025 Sep 5;11(36):eady1289. doi: 10.1126/sciadv.ady1289. Epub 2025 Sep 3.Published September 3, 2025
Breast cancer is hallmarked by phenotypic transitions enabling abnormal cell proliferation and invasion. The stress-protective transcription factor heat shock factor 2 (HSF2) is associated with... Read more
Timo Seitz et al.Mol Nutr Food Res. 2025 Sep 1:e70225. doi: 10.1002/mnfr.70225. Online ahead of print.Published September 2, 2025
Breast milk proteome comprises hundreds of bioactive proteins supporting infant development. The extent to which maternal metabolic conditions modify the proteome is poorly known. This... Read more
Risto O Juvonen et al.Eur J Pharm Sci. 2025 Aug 28:107249. doi: 10.1016/j.ejps.2025.107249. Online ahead of print.Published August 30, 2025
Sulfonation is one of drug metabolism reactions affecting homeostasis of estrogens. C-3 aryl substituted 7-hydroxycoumarins are fluorescent estrogen mimetics; i.e., the hydroxyl groups of both... Read more
Pernilla Syrjä et al.J Vet Intern Med. 2025 Sep-Oct;39(5):e70223. doi: 10.1111/jvim.70223.Published August 27, 2025
Cholesterol ester storage disease (CESD) is a rare genetic lysosomal storage disorder resulting from lower lysosomal acid lipase (LAL) activity. LAL is an essential enzyme... Read more
Yuchen Su et al.RSC Chem Biol. 2025 Jul 30. doi: 10.1039/d5cb00104h. Online ahead of print.Published August 18, 2025
A common approach in living medicine engineering is modifying cell surfaces with nanomedicines to form nanoparticle-cell conjugates. Despite various available strategies, limited research has examined... Read more
Nicole Hernández et al.PLoS One. 2025 Aug 18;20(8):e0321658. doi: 10.1371/journal.pone.0321658. eCollection 2025.Published August 18, 2025
BACKGROUND: Mammography is the most common imaging modality for the detection of breast cancer. Artificial intelligence algorithms for mammography analysis have shown promising performance for... Read more
Herbert Michlmayr et al.J Biol Chem. 2025 Aug 14:110600. doi: 10.1016/j.jbc.2025.110600. Online ahead of print.Published August 16, 2025
Deoxynivalenol (DON) is a toxicologically relevant trichothecene mycotoxin frequently found in cereal products. It is a virulence factor produced by the plant pathogen Fusarium graminearum... Read more
