Publications

    Publication
    LIMA1-alpha staining predicts curative intent surgery response in HPV negative head and neck cancer 
    Xi Qiao et al. EMBO Mol Med. 2025 Jul 17. doi: 10.1038/s44321-025-00266-8. Online ahead of print. Published July 17, 2025
    In many solid cancer types, surgery alone could be a sufficient first therapy option for a significant number of cancer patients. However, there are currently... Read more
    Publication
    EPLINα controls integrin recycling from Rab21 endosomes to drive breast cancer cell migration 
    Niklas Z Jäntti et al. Dev Cell. 2025 Jul 9:S1534-5807(25)00403-4. doi: 10.1016/j.devcel.2025.06.025. Online ahead of print. Published July 16, 2025
    Epithelial protein lost in neoplasm (EPLIN), an actin-binding protein, has been described as both a tumor promoter and tumor suppressor in different cancers. The roles... Read more
    Publication
    Extracellular vesicles bearing vimentin drive epithelial-mesenchymal transition 
    Sepideh Parvanian et al. Mol Cell Proteomics. 2025 Jul 4:101028. doi: 10.1016/j.mcpro.2025.101028. Online ahead of print. Published July 6, 2025
    Epithelial-mesenchymal transition (EMT) is a key biological process in physiological and pathological conditions, spanning development, wound healing, and cancer. Vimentin, a key cytoskeletal intermediate filament... Read more
    Publication
    Structural Repetition Detector for multi-scale quantitative mapping of molecular complexes through microscopy 
    Afonso Mendes et al. Nat Commun. 2025 Jul 1;16(1):5767. doi: 10.1038/s41467-025-60709-1. Published July 2, 2025
    From molecules to organelles, cells exhibit recurring structural motifs across multiple scales. Understanding these structures provides insights into their functional roles. While super-resolution microscopy can... Read more
    Publication
    Sketching T cell atlases in the single-cell era: challenges and recommendations 
    Itana Bojović et al. Immunol Cell Biol. 2025 Jun 29. doi: 10.1111/imcb.70040. Online ahead of print. Published June 29, 2025
    Recent advances in single-cell technologies have enabled the creation of comprehensive cell atlases, reference maps of various cell types within organisms. Here we specifically focus... Read more
    Publication
    In situ construction of ossification micro-units for critical bone regeneration via sustained lifting of epigenetic suppression 
    Wu Yang et al. J Control Release. 2025 Jun 23:113978. doi: 10.1016/j.jconrel.2025.113978. Online ahead of print. Published June 25, 2025
    Critical-sized bone defects present significant clinical challenges due to insufficient stem cell recruitment, epigenetic suppression of osteogenesis, and inadequate mineralization. Among the epigenetic suppression mechanisms,... Read more
    Publication
    Cytoskeletal crosstalk in macrophages: Vimentin drives ECM remodeling in tumor invasion and tissue plasticity 
    John E Eriksson et al. Dev Cell. 2025 Jun 23;60(12):1655-1657. doi: 10.1016/j.devcel.2025.05.015. Published June 24, 2025
    In this issue of Developmental Cell, Huang et al. assess the role of vimentin intermediate filaments during extracellular matrix (ECM) degradation by macrophages. Vimentin stabilizes... Read more
    Publication
    Integrin β1 activity controls colony morphology during human pluripotent stem cell state transitions 
    Maria E Taskinen et al. Stem Cell Reports. 2025 Jun 17:102538. doi: 10.1016/j.stemcr.2025.102538. Online ahead of print. Published June 20, 2025
    Integrin β1-mediated adhesion is dispensable in early mouse embryogenesis (pre-implantation) but indispensable post-implantation, suggesting distinct roles for β1-integrin-mediated adhesions in the naive (pre-implantation) versus primed... Read more
    Publication
    The Next Frontier: Unveiling Novel Approaches for Combating Multidrug-Resistant Bacteria 
    Praveen Mallari et al. Pharm Res. 2025 Jun 16. doi: 10.1007/s11095-025-03871-x. Online ahead of print. Published June 16, 2025
    CONCLUSION: Despite the substantial obstacles to getting bench findings to the patient, numerous scientists are still working towards this goal. Both the application of antibiotic... Read more
    Publication
    A metabolite-based resistance mechanism against malaria 
    Ana Figueiredo et al. Science. 2025 Jun 12;388(6752):eadq6741. doi: 10.1126/science.adq6741. Epub 2025 Jun 12. Published June 12, 2025
    Jaundice is a common presentation of Plasmodium falciparum malaria, which arises from the accumulation of circulating bilirubin. It is not understood whether it represents an... Read more
    Publication
    NRF2-mediated persistent adaptation of oesophageal adenocarcinoma cells to HER2 inhibition 
    Wei Zhang et al. Oncogene. 2025 Jun 5. doi: 10.1038/s41388-025-03459-0. Online ahead of print. Published June 5, 2025
    The human epidermal growth factor receptor 2 (HER2, also known as ERBB2) is a commonly over-expressed oncoprotein in oesophageal adenocarcinoma (OAC). Nonetheless, HER2-blocking agents have... Read more
    Publication
    Biochemical and structural characterization of chlorite dismutase enzyme from Pseudomonas aeruginosa 
    Dimitrios V Nokas et al. FEBS J. 2025 Jun 3. doi: 10.1111/febs.70151. Online ahead of print. Published June 3, 2025
    Industrialization and urbanization have caused serious contamination of water bodies, and the removal of chemical contaminants has become a major challenge. Chlorite is a harmful... Read more
    Last updated on June 25, 2025